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Sumitomo Chemical Co Ltd
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Sumitomo Chemical Co Ltd
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Priority to JP55133823ApriorityCriticalpatent/JPS5758632A/en
Publication of JPS5758632ApublicationCriticalpatent/JPS5758632A/en
Organic Low-Molecular-Weight Compounds And Preparation Thereof
(AREA)
Abstract
PURPOSE: To separate an enantiomeric mixture of compounds having -NH linked to an atom at the asymmetric carbon atom or the α-position to the asymmetric carbon atom, by using an optically active tartaric ester as a stationary phase in the gas chromatography.
CONSTITUTION: An enantiomeric mixture of compounds, e.g. N-acylated amino acid ester or N-acylated amino acid amide, having -NH linked to the asymmetric carbon atom or at the α-position to the assymetric carbon atom is separated by using a levorotatory or dextrorotatory tartaric ester, e.g. l-methyl L-tartrate, ex- pressed by the formula (* is asymmetric carbon atom; R and R' are alkyl, aralkyl, aryl or cycloalkyl which may have a substituent group) as a stationary phase in the gas chromatography. A capillar column is preferably used as the gas chromatographic column.
COPYRIGHT: (C)1982,JPO&Japio
JP55133823A1980-09-251980-09-25Gas chromatographic separating method of enantiometric mixture with tartaric ester
PendingJPS5758632A
(en)
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