JPS5756750A - Separating method for optical isomers of alcohols having asymmetric carbon atom by gas chromatography - Google Patents
Separating method for optical isomers of alcohols having asymmetric carbon atom by gas chromatographyInfo
- Publication number
- JPS5756750A JPS5756750A JP55132032A JP13203280A JPS5756750A JP S5756750 A JPS5756750 A JP S5756750A JP 55132032 A JP55132032 A JP 55132032A JP 13203280 A JP13203280 A JP 13203280A JP S5756750 A JPS5756750 A JP S5756750A
- Authority
- JP
- Japan
- Prior art keywords
- deriv
- gas chromatography
- asymmetric carbon
- optical isomers
- alcohols
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
- C07C29/74—Separation; Purification; Use of additives, e.g. for stabilisation
- C07C29/76—Separation; Purification; Use of additives, e.g. for stabilisation by physical treatment
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
PURPOSE:To separate directly and easily the mixture of optical isomers of straight chain or cyclic alcohols having hydroxyl group attached to the asymmetric carbon atom, by applying gas chromatography using an optically active exter deriv. of peptide or an amide deriv. of amino acid as a stationary phase. CONSTITUTION:A mixture of optical isomer of alcohols shown in formulaI(where Ar is aryl, R1 is alkyl, halogen substituted alkyl or alkynyl) or cyclopentenon deriv. shown in formula II (where R2 is alkenyl or alkynyl) is separated directly by gas chromatography that uses an optically active s-triazine deriv. contg. one or more asymmetric carbon atoms shown in formula III[where X1, X2 is -NH-E1-COOR3, -N(R4, R5), -NH-E2-COOR3, OR6 or halogen, in this case, E1 is residue forming peptide linkage, E2 is a residue of amino acid, R3 is residue of R3OH, R4R6 is H, alkyl or cyclo alkyl]as a stationary phase. According to this procedure, ratio of optical isomers is easily analyzed.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP55132032A JPS5756750A (en) | 1980-09-22 | 1980-09-22 | Separating method for optical isomers of alcohols having asymmetric carbon atom by gas chromatography |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP55132032A JPS5756750A (en) | 1980-09-22 | 1980-09-22 | Separating method for optical isomers of alcohols having asymmetric carbon atom by gas chromatography |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS5756750A true JPS5756750A (en) | 1982-04-05 |
Family
ID=15071897
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP55132032A Pending JPS5756750A (en) | 1980-09-22 | 1980-09-22 | Separating method for optical isomers of alcohols having asymmetric carbon atom by gas chromatography |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5756750A (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1983004103A1 (en) * | 1982-05-19 | 1983-11-24 | Sumitomo Chemical Co., Ltd. | Grafted chromatographic filler and method for analyzing enantiomer mixture using same |
WO1998000382A1 (en) * | 1996-07-02 | 1998-01-08 | Toray Industries, Inc. | Processes for the preparation of optically active ketones |
-
1980
- 1980-09-22 JP JP55132032A patent/JPS5756750A/en active Pending
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1983004103A1 (en) * | 1982-05-19 | 1983-11-24 | Sumitomo Chemical Co., Ltd. | Grafted chromatographic filler and method for analyzing enantiomer mixture using same |
WO1998000382A1 (en) * | 1996-07-02 | 1998-01-08 | Toray Industries, Inc. | Processes for the preparation of optically active ketones |
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