JPS5790002A - Cellulose sulfate containing heparin-like property and its production - Google Patents
Cellulose sulfate containing heparin-like property and its productionInfo
- Publication number
- JPS5790002A JPS5790002A JP55165786A JP16578680A JPS5790002A JP S5790002 A JPS5790002 A JP S5790002A JP 55165786 A JP55165786 A JP 55165786A JP 16578680 A JP16578680 A JP 16578680A JP S5790002 A JPS5790002 A JP S5790002A
- Authority
- JP
- Japan
- Prior art keywords
- cellulose
- cellulose sulfate
- formicellulose
- sulfating
- precipitated
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229920002678 cellulose Polymers 0.000 title abstract 5
- 239000001913 cellulose Substances 0.000 title abstract 5
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 title abstract 4
- 150000001412 amines Chemical class 0.000 abstract 2
- 239000013078 crystal Substances 0.000 abstract 2
- 239000002244 precipitate Substances 0.000 abstract 2
- 238000006467 substitution reaction Methods 0.000 abstract 2
- 230000001180 sulfating effect Effects 0.000 abstract 2
- QAOWNCQODCNURD-UHFFFAOYSA-N sulfuric acid group Chemical group S(O)(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 abstract 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Chemical group OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 abstract 1
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 abstract 1
- 239000003463 adsorbent Substances 0.000 abstract 1
- 150000001408 amides Chemical class 0.000 abstract 1
- 230000002429 anti-coagulating effect Effects 0.000 abstract 1
- 125000003827 glycol group Chemical group 0.000 abstract 1
- 229960002897 heparin Drugs 0.000 abstract 1
- 229920000669 heparin Polymers 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000003472 neutralizing effect Effects 0.000 abstract 1
- 239000000047 product Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B5/00—Preparation of cellulose esters of inorganic acids, e.g. phosphates
- C08B5/14—Cellulose sulfate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Materials Engineering (AREA)
- Biochemistry (AREA)
- Polymers & Plastics (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP55165786A JPS5790002A (en) | 1980-11-27 | 1980-11-27 | Cellulose sulfate containing heparin-like property and its production |
| CA000390539A CA1176631A (en) | 1980-11-27 | 1981-11-20 | Cellulose sulfate salt having anti-coagulating action and process for preparing same |
| US06/324,918 US4389523A (en) | 1980-11-27 | 1981-11-25 | Cellulose sulfate salt having anti-coagulating action and process for preparing same |
| DE8181305569T DE3171428D1 (en) | 1980-11-27 | 1981-11-25 | Cellulose sulfate salt having anti-coagulating action and process for preparing same |
| EP81305569A EP0053473B1 (en) | 1980-11-27 | 1981-11-25 | Cellulose sulfate salt having anti-coagulating action and process for preparing same |
| AU77912/81A AU529691B2 (en) | 1980-11-27 | 1981-11-26 | Cellulose sulfate salt having anti-coagulating action |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP55165786A JPS5790002A (en) | 1980-11-27 | 1980-11-27 | Cellulose sulfate containing heparin-like property and its production |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS5790002A true JPS5790002A (en) | 1982-06-04 |
| JPS6356242B2 JPS6356242B2 (enExample) | 1988-11-07 |
Family
ID=15818974
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP55165786A Granted JPS5790002A (en) | 1980-11-27 | 1980-11-27 | Cellulose sulfate containing heparin-like property and its production |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US4389523A (enExample) |
| EP (1) | EP0053473B1 (enExample) |
| JP (1) | JPS5790002A (enExample) |
| AU (1) | AU529691B2 (enExample) |
| CA (1) | CA1176631A (enExample) |
| DE (1) | DE3171428D1 (enExample) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2006274245A (ja) * | 2005-03-01 | 2006-10-12 | Chisso Corp | 硫酸化セルロース及びその塩から選ばれた化合物並びに皮膚炎治療剤 |
| JP2008533231A (ja) * | 2005-03-11 | 2008-08-21 | オーストリアノバ バイオテクノロジー ゲーエムベーハー | 特性の改良された硫酸セルロースを製造する方法 |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4520017A (en) * | 1983-02-04 | 1985-05-28 | Tunc Deger C | Method of reducing nutrient absorption |
| US4623539A (en) * | 1983-02-04 | 1986-11-18 | Tunc Deger C | Nutrient barrier polysaccharide compositions and method of use |
| US5512672A (en) * | 1988-07-07 | 1996-04-30 | Ajinomoto Co., Inc. | Curdlan sulfate |
| US5063210A (en) * | 1989-04-20 | 1991-11-05 | Lange Iii Louis G | Use of sulfated polysaccharides to decrease cholesterol and fatty acid absorption |
| US5484777A (en) * | 1989-04-20 | 1996-01-16 | Lange, Iii; Louis G. | Pancreatic cholesterol esterase inhibitor |
| US5017565A (en) * | 1989-04-20 | 1991-05-21 | Lange Iii Louis G | Use of sulfated polysaccharides to inhibit pancreatic cholesterol esterase |
| US5561114A (en) * | 1992-09-25 | 1996-10-01 | Otsuka Pharmaceutical Factory Inc. | Adsorbent for cellular fibronectin, a method for fractional purification of fibronectin and a method of hemocatharisis |
| US5378828A (en) * | 1993-09-02 | 1995-01-03 | Dextran Products Limited | Process for preparing soluble alkali metal salts of cellulose sulfate using chlorosulfuric acid and pyridine |
| CA2160440C (en) | 1994-10-13 | 1998-08-25 | Louis G. Lange, Iii | Method of manufacturing non-absorbable synthetic sulfated polysaccharides |
| US7071174B1 (en) | 1994-10-13 | 2006-07-04 | Cv Therapeutics, Inc. | Method and composition for inhibiting cholesterol esterase |
| US5521303A (en) * | 1994-10-13 | 1996-05-28 | Cv Therapeutics, Inc. | Method of manufacturing non-absorbable synthetic sulfated polysaccharides |
| US6063773A (en) * | 1995-09-29 | 2000-05-16 | Polydex Pharmaceuticals Ltd. | Cellulose sulfate for use as antimicrobial and contraceptive agent |
| EP1249240A4 (en) * | 2000-01-14 | 2003-03-19 | Otsuka Pharma Co Ltd | INHIBITORS OF SODIUM ION ABSORPTION, AND PROPHYLACTIC OR THERAPEUTIC AGENTS AND FOOD PRODUCTS CONTAINING SAID INHIBITORS |
| EP1982727A1 (en) | 2007-04-17 | 2008-10-22 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Method for purification of viral proteins |
| DE102007035322B4 (de) | 2007-07-25 | 2011-11-17 | Friedrich-Schiller-Universität Jena | Verfahren zur Herstellung wasserlöslicher, niedrig substituierter Cellulosesulfate |
| CN101284878B (zh) * | 2008-05-27 | 2010-06-02 | 浙江大学 | 一种水溶性淀粉硫酸钠的制备方法 |
| WO2010127451A1 (en) * | 2009-05-06 | 2010-11-11 | Fpinnovations | Crystalline sulphated cellulose ii and its production from sulphuric acid hydrolysis of celulose |
| DE102013017014B4 (de) | 2013-10-14 | 2017-03-30 | Sartorius Stedim Biotech Gmbh | Sulfatierte Cellulosehydrat-Membran, Verfahren zur ihrer Herstellung und Verwendung der Membran als Adsorptionsmembran für die Virenaufreinigung |
| CN114409810A (zh) * | 2021-12-22 | 2022-04-29 | 深圳华源再生医学有限公司 | 一种高分子量纤维素硫酸酯及其制备方法和应用 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2753337A (en) * | 1953-09-23 | 1956-07-03 | Hercules Powder Co Ltd | Process for preparing sulfuric acid esters of cellulose |
| US3624069A (en) * | 1965-06-28 | 1971-11-30 | Kelco Co | Process of preparing a gellable colloidal cellulose sulfate and product |
| US3528963A (en) * | 1969-03-24 | 1970-09-15 | Hercules Inc | Process for preparing cellulose sulfate salts |
| US3639665A (en) * | 1969-04-10 | 1972-02-01 | Kelco Co | Process of preparing a gellable collodial cellulose sulfate |
| US4141746A (en) * | 1970-05-25 | 1979-02-27 | Schweiger Richard Georg | Cellulose sulfate esters |
| US3609377A (en) * | 1970-06-16 | 1971-09-28 | Kelco Co | Method for preparing alkali metal salts of cellulose sulfate and stabilized alkali metal salts of cellulose sulfate |
| US4064342A (en) * | 1974-07-30 | 1977-12-20 | Lion Fat And Oil Co., Ltd. | Method of manufacturing sulfated cellulose |
-
1980
- 1980-11-27 JP JP55165786A patent/JPS5790002A/ja active Granted
-
1981
- 1981-11-20 CA CA000390539A patent/CA1176631A/en not_active Expired
- 1981-11-25 US US06/324,918 patent/US4389523A/en not_active Expired - Lifetime
- 1981-11-25 EP EP81305569A patent/EP0053473B1/en not_active Expired
- 1981-11-25 DE DE8181305569T patent/DE3171428D1/de not_active Expired
- 1981-11-26 AU AU77912/81A patent/AU529691B2/en not_active Ceased
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2006274245A (ja) * | 2005-03-01 | 2006-10-12 | Chisso Corp | 硫酸化セルロース及びその塩から選ばれた化合物並びに皮膚炎治療剤 |
| JP2008533231A (ja) * | 2005-03-11 | 2008-08-21 | オーストリアノバ バイオテクノロジー ゲーエムベーハー | 特性の改良された硫酸セルロースを製造する方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| AU529691B2 (en) | 1983-06-16 |
| CA1176631A (en) | 1984-10-23 |
| JPS6356242B2 (enExample) | 1988-11-07 |
| AU7791281A (en) | 1982-07-15 |
| EP0053473A1 (en) | 1982-06-09 |
| US4389523A (en) | 1983-06-21 |
| EP0053473B1 (en) | 1985-07-17 |
| DE3171428D1 (en) | 1985-08-22 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JPS5790002A (en) | Cellulose sulfate containing heparin-like property and its production | |
| ATE8998T1 (de) | Fragmentiertes heparin mit selektiver antikoagulierender wirksamkeit und verfahren zu dessen herstellung. | |
| MX9100443A (es) | Proceso para la produccion de resinas de poliaminopoliamida y epiclorohidrina mejorada | |
| JPS572656A (en) | Decoloration and purification of stevia extract | |
| ES8201596A1 (es) | Procedimiento de obtencion de mucopolisacaridos | |
| IT1221734B (it) | Ursodesossicolico solfato acido sale sodico | |
| ATE89008T1 (de) | Modifizierung von alginaten oder sonstigen uronsaeureverbindungen durch co2-behandlung. | |
| JPS5661429A (en) | Production of aromatic polyester-polycarbonate | |
| JPS5391086A (en) | Imparting method for water absorption and retention properties | |
| JPS5655426A (en) | Production of polyester | |
| JPS5213585A (en) | Preparation of cellulose sulfate | |
| JPS542396A (en) | Purification of urokinase | |
| JPS5391189A (en) | Preparation of d-n-carbamoyl-alpha-amino acids | |
| ES484100A1 (es) | Un procedimiento para la preparacion de corticosteroides de-rivados de ciclopentanofenantreno | |
| EP0297397A3 (de) | Herstellung von Diazo-und Azoverbindungen | |
| IE781891L (en) | Fibrous milk protein product. | |
| JPS5316048A (en) | Cathod-depositing coating composition and its preparation | |
| JPS52105199A (en) | Isolation of acidic polysaccharide | |
| JPS5660699A (en) | Dehydration of sludge | |
| JPS5513755A (en) | Method of cleaning device for polyester production | |
| JPS5397251A (en) | Treatment of turbid water | |
| JPS568243A (en) | Preparation of vulcanized fiber | |
| JPS5535011A (en) | Preparation of novel substance inhibiting formation and storage of lipid | |
| JPS6462301A (en) | Production of substance having gelling ability | |
| SU636263A1 (ru) | Способ нейтрализации гидролизаторов растительного сырь |