JPS5788163A - Preparation of o-aminomethylphenylacetyl lactam - Google Patents

Preparation of o-aminomethylphenylacetyl lactam

Info

Publication number
JPS5788163A
JPS5788163A JP16265680A JP16265680A JPS5788163A JP S5788163 A JPS5788163 A JP S5788163A JP 16265680 A JP16265680 A JP 16265680A JP 16265680 A JP16265680 A JP 16265680A JP S5788163 A JPS5788163 A JP S5788163A
Authority
JP
Japan
Prior art keywords
acid
polyphosphoric acid
methylphenylacetamide
dehydration
polyphosphoric
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP16265680A
Other languages
Japanese (ja)
Inventor
Mamoru Nakai
Takuji Enomiya
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ube Corp
Original Assignee
Ube Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ube Industries Ltd filed Critical Ube Industries Ltd
Priority to JP16265680A priority Critical patent/JPS5788163A/en
Publication of JPS5788163A publication Critical patent/JPS5788163A/en
Pending legal-status Critical Current

Links

Abstract

PURPOSE: To obtain the titled compound useful as a raw material for preparing o-aminomethylphenylacetic acid in high yield, by reacting methylphenylacetamide with paraformaldehyde through dehydration in the presence of polyphosphoric acid as a dehydrating agent.
CONSTITUTION: Methylphenylacetamide of formulaIis reacted with paraformaldehyede in the presence of polyphosphoric acid at 110W160°C for 1W20hr through dehydration to give the aimed compound of formula II. The polyphosphoric acid is a viscous sirupy substance obtained by dehydrating and concentrating orthophosphoric acid under heating, and consists of orthophosphoric acid, pyrophosphric acid, tetrapolyphosphoric acid, etc. The P2O5 content of 77W86wt% may be preferred. The amount of the polyphosphoric acid used is preferably 200W800g based on one mole compound of formulaI.
USE: A raw material for preparing o-aminomethylphenylacetic acid which is an intermediate for cephalosporin antibiotics.
COPYRIGHT: (C)1982,JPO&Japio
JP16265680A 1980-11-20 1980-11-20 Preparation of o-aminomethylphenylacetyl lactam Pending JPS5788163A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP16265680A JPS5788163A (en) 1980-11-20 1980-11-20 Preparation of o-aminomethylphenylacetyl lactam

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP16265680A JPS5788163A (en) 1980-11-20 1980-11-20 Preparation of o-aminomethylphenylacetyl lactam

Publications (1)

Publication Number Publication Date
JPS5788163A true JPS5788163A (en) 1982-06-01

Family

ID=15758767

Family Applications (1)

Application Number Title Priority Date Filing Date
JP16265680A Pending JPS5788163A (en) 1980-11-20 1980-11-20 Preparation of o-aminomethylphenylacetyl lactam

Country Status (1)

Country Link
JP (1) JPS5788163A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH03124531U (en) * 1990-03-30 1991-12-17

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH03124531U (en) * 1990-03-30 1991-12-17

Similar Documents

Publication Publication Date Title
JPS5788163A (en) Preparation of o-aminomethylphenylacetyl lactam
JPS56138151A (en) Preparation of beta-chloroalanine
JPS57149271A (en) Preparation of o-aminomethylphenylacetic lactam
JPS5711981A (en) Theobromine derivative and its preparation
JPS5651478A (en) 3-carbamoyl-pyrazolo 1,5-a pyridine and its preparation
JPS56140951A (en) 4- perfluoro-3- 1-methylethyl -4-methyl-2-penten-2-oxy - phthalic acid and its preparation
JPS5799558A (en) 2-nitro-6-hydroxy-beta-phenylethyl alcoholic derivative and its preparation
JPS56133220A (en) Preparation of aldehyde
JPS5520743A (en) Alpha-substituted amino-epsilon-caprolactam
JPS5528941A (en) Preparation of pinacolone
JPS51138658A (en) Process f or preparation of novel resin
JPS56140988A (en) 4- perfluoro-3- 1-methylethyl -4-methyl-2-pentene-2-oxy phthalic anhydride and its preparation
JPS51138611A (en) Process for preparation of delta- alkoxyl-alpha,beta-unsaturated aldehyde
JPS5781459A (en) Preparation of 4-(3-isopropylamino-2-hydroxypropoxy) indole
JPS55145668A (en) Preparation of alpha-dimethylamino-epsilon-caprolactam
JPS57171992A (en) Novel secalonic acid derivative and its preparation
JPS5585568A (en) Quinolinone-imine derivative and its preparation
JPS55122783A (en) Preparation of porfiromycin derivative
JPS5531087A (en) Preparation of 5-acetyl-1,2,6-trimethyl-tricyclo 5.3.2.02,7 dodec-5-ene
JPS5767594A (en) Preparation of 3-deoxy-3-iodo-glucose derivative
JPS543059A (en) Preparation of tryptophane
JPS5673086A (en) Preparation of cephalosporin compound
JPS5446741A (en) Preparation of hydroxy-phenyl glycine derivatives
JPS5594374A (en) Preparation of orotic acid
JPS5759872A (en) Novel imidazole derivative and its preparation