JPS5772914A - Antitumor agent - Google Patents
Antitumor agentInfo
- Publication number
- JPS5772914A JPS5772914A JP55148485A JP14848580A JPS5772914A JP S5772914 A JPS5772914 A JP S5772914A JP 55148485 A JP55148485 A JP 55148485A JP 14848580 A JP14848580 A JP 14848580A JP S5772914 A JPS5772914 A JP S5772914A
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- compound
- antitumor agent
- formulaiin
- inhibitory action
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
- C07F9/10—Phosphatides, e.g. lecithin
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N57/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds
- A01N57/10—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-oxygen bonds or phosphorus-to-sulfur bonds
- A01N57/12—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-oxygen bonds or phosphorus-to-sulfur bonds containing acyclic or cycloaliphatic radicals
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N57/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds
- A01N57/10—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-oxygen bonds or phosphorus-to-sulfur bonds
- A01N57/16—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-oxygen bonds or phosphorus-to-sulfur bonds containing heterocyclic radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/03—Ethers having all ether-oxygen atoms bound to acyclic carbon atoms
- C07C43/04—Saturated ethers
- C07C43/13—Saturated ethers containing hydroxy or O-metal groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
- C07F9/091—Esters of phosphoric acids with hydroxyalkyl compounds with further substituents on alkyl
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/576—Six-membered rings
- C07F9/58—Pyridine rings
Priority Applications (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP55148485A JPS5772914A (en) | 1980-10-22 | 1980-10-22 | Antitumor agent |
DE8181304732T DE3171325D1 (en) | 1980-10-22 | 1981-10-12 | Tridecyloxy- or tetradecyloxy-propane derivatives, and their use |
EP81304732A EP0050460B1 (en) | 1980-10-22 | 1981-10-12 | Tridecyloxy- or tetradecyloxy-propane derivatives, and their use |
US06/311,876 US4426525A (en) | 1980-10-22 | 1981-10-15 | Certain phosphoric acid ester derivatives of 1,3-dioxy propane |
CA000388394A CA1176254A (en) | 1980-10-22 | 1981-10-21 | Tridecyl or tetradecyl phospholipids |
US06/559,634 US4544512A (en) | 1980-10-22 | 1983-12-09 | Tridecyloxy- or tetradecyloxy-propane derivatives |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP55148485A JPS5772914A (en) | 1980-10-22 | 1980-10-22 | Antitumor agent |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS5772914A true JPS5772914A (en) | 1982-05-07 |
Family
ID=15453804
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP55148485A Pending JPS5772914A (en) | 1980-10-22 | 1980-10-22 | Antitumor agent |
Country Status (5)
Country | Link |
---|---|
US (2) | US4426525A (ja) |
EP (1) | EP0050460B1 (ja) |
JP (1) | JPS5772914A (ja) |
CA (1) | CA1176254A (ja) |
DE (1) | DE3171325D1 (ja) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5829794A (ja) * | 1981-07-31 | 1983-02-22 | Fujisawa Pharmaceut Co Ltd | 燐脂質誘導体 |
Families Citing this family (46)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4562179A (en) * | 1982-04-19 | 1985-12-31 | Fujisawa Pharmaceutical Co., Ltd. | Phospholipid derivatives, and pharmaceutical composition of the same |
JPS58192825A (ja) * | 1982-05-06 | 1983-11-10 | Takeda Chem Ind Ltd | グリセロール誘導体 |
DE3239858A1 (de) * | 1982-07-06 | 1984-01-12 | Max Planck Gesellschaft zur Förderung der Wissenschaften e.V., 3400 Göttingen | Neue d-mannitderivate als ausgangsprodukte zur synthese von phospholipiden |
US5189017A (en) * | 1982-07-23 | 1993-02-23 | Ciba-Geigy Corporation | Use of sugar derivatives for the prophylaxis and treatment of virus infections |
US5334583A (en) * | 1982-07-23 | 1994-08-02 | Ciba-Geigy Corp. | Use of sugar derivatives for the prophylaxis and treatment of virus infections |
JPS5984824A (ja) * | 1982-11-08 | 1984-05-16 | Takeda Chem Ind Ltd | 抗腫瘍剤 |
JPS59184195A (ja) * | 1983-04-04 | 1984-10-19 | Takeda Chem Ind Ltd | グリセロ−ル誘導体 |
JPS6081193A (ja) * | 1983-10-11 | 1985-05-09 | Takeda Chem Ind Ltd | リン脂質 |
JPS6081194A (ja) * | 1983-10-11 | 1985-05-09 | Takeda Chem Ind Ltd | ケトアルキルリン脂質 |
US4650791A (en) * | 1984-01-11 | 1987-03-17 | Takedo Chemical Industries, Ltd. | Certain 3-alkoxy-2-cyclic-imido-propyl-phosphate-ethyl-cyclic ammonium hydroxide inner salts which inhibit activities of platelet activating factor |
US4737518A (en) * | 1984-04-03 | 1988-04-12 | Takeda Chemical Industries, Ltd. | Lipid derivatives, their production and use |
ATE45744T1 (de) * | 1984-07-25 | 1989-09-15 | Ciba Geigy Ag | Phosphatidylverbindungen, verfahren zu ihrer herstellung und ihre verwendung. |
US4710579A (en) * | 1984-11-09 | 1987-12-01 | Takeda Chemical Industries, Ltd. | 2-(acetoacetyloxy)-3-(octadecyloxy)propyl-3-trimethylammoniopropyl phosphate or a pharmaceutically acceptable salt thereof |
JPS61267592A (ja) * | 1985-01-16 | 1986-11-27 | Sankyo Co Ltd | 燐酸エステル誘導体、その製法およびそれを含有する抗腫瘍剤 |
US4647685A (en) * | 1985-04-25 | 1987-03-03 | Eli Lilly And Company | 2-alkoxy-1-((2-trialkylaminoethoxy)phosphinyloxy)-alkenes and alkynes, hydroxy inner salts |
US4619917A (en) * | 1985-07-18 | 1986-10-28 | Sandoz Pharm. Corp. | Substituted 2-furanyl- or 5-oxo-2-furanyl methoxy phosphoryl alkyl cyclimmonium salts |
EP0213082B1 (en) * | 1985-08-30 | 1989-10-18 | Sandoz Ag | Substituted hydroxy-heterocyclyl-alkoxy phosphinyloxy trialkylaminium hydroxide inner salt oxides, processes for their preparation and their use as pharmaceuticals |
US4873322A (en) * | 1986-01-24 | 1989-10-10 | Ciba-Geigy Corporation | Saccharide derivatives and processes for their manufacture |
US4845219A (en) * | 1986-07-30 | 1989-07-04 | Takeda Chemical Industries, Ltd. | Nitrogen- and sulfur-containing lipid compounds their production and use |
CN1017435B (zh) * | 1987-03-24 | 1992-07-15 | 日本化学医药株式会社 | 新的甘油衍生物的制备方法 |
US5145844A (en) * | 1987-07-23 | 1992-09-08 | Hoechst-Roussel Pharmaceuticals Incorporated | Methods of using hydroxy-, alkoxy- and benzyloxy-substituted phospholipids to treat phospholipase A2 -mediated conditions and to alleviate pain |
US5030733A (en) * | 1987-07-23 | 1991-07-09 | Hoechst-Roussel Pharmaceticals Incorporated | Hydroxy-, alkoxy- and benzyloxy-substituted phospholipids |
US5036152A (en) * | 1988-03-10 | 1991-07-30 | Hoechst-Roussel Pharmaceuticals Incorporated | Alkoxycarbonylalkylphospholipids and alkylaminocarbonylalkylphospholipids |
CA2001401A1 (en) * | 1988-10-25 | 1990-04-25 | Claude Piantadosi | Quaternary amine containing ether or ester lipid derivatives and therapeutic compositions |
WO1994002153A1 (en) * | 1992-07-22 | 1994-02-03 | Boehringer Mannheim Gmbh | Use of sulphur containing phospholipids for treating leishmaniasis |
US5811568A (en) * | 1992-10-08 | 1998-09-22 | Shaman Pharmaceuticals, Inc. | Process for the preparation of mono- and bis(phosphocholine) derivatives which have antifungal activity |
US5681829A (en) * | 1992-10-08 | 1997-10-28 | Shaman Pharmaceuticals, Inc. | Class of phosphocholine derivatives having antifungal activity |
WO1994028908A2 (en) * | 1993-06-10 | 1994-12-22 | Wake Forest University | (phospho)lipids for combatting hepatitis b virus infection |
US5995645A (en) * | 1993-08-18 | 1999-11-30 | Applied Spectral Imaging Ltd. | Method of cancer cell detection |
CA2197319C (en) * | 1994-08-29 | 2009-01-27 | Louis S. Kucera | Lipid analogs for treating viral infections |
US7135584B2 (en) * | 1995-08-07 | 2006-11-14 | Wake Forest University | Lipid analogs for treating viral infections |
ZA962880B (en) * | 1995-04-12 | 1997-03-17 | Procter & Gamble | A pharmaceutical composition for inhibiting the growth of viruses and cancers |
US5656615A (en) * | 1995-04-12 | 1997-08-12 | The Procter & Gamble Company | Pharmaceutical composition for inhibiting the growth of cancers and viruses in mammals |
BR9604973A (pt) * | 1995-04-12 | 1998-06-09 | Procter & Gamble | Uma composição farmacêutica contendo carbamatos de n-cloro fenila e tiocarbamatos de n-cloro fenila para inibição de crescimento de vírus e cânceres |
US5665713A (en) * | 1995-04-12 | 1997-09-09 | Procter & Gamble Company | Pharmaceutical composition for inhibiting the growth of viruses and cancers |
US6177460B1 (en) | 1995-04-12 | 2001-01-23 | The Procter & Gamble Company | Method of treatment for cancer or viral infections |
US6686391B2 (en) | 1995-08-04 | 2004-02-03 | University Of Arizona Foundation | N-chlorophenylcarbamate and N-chlorophenylthiocarbamate compositions |
US5932242A (en) * | 1996-10-15 | 1999-08-03 | The Liposome Company, Inc. | Ether lipid-containing pharmaceutical compositions and therapeutic uses thereof |
US7026469B2 (en) * | 2000-10-19 | 2006-04-11 | Wake Forest University School Of Medicine | Compositions and methods of double-targeting virus infections and cancer cells |
US7309696B2 (en) | 2000-10-19 | 2007-12-18 | Wake Forest University | Compositions and methods for targeting cancer cells |
US6706931B2 (en) * | 2000-12-21 | 2004-03-16 | Shell Oil Company | Branched primary alcohol compositions and derivatives thereof |
EP1397326A2 (en) * | 2001-05-29 | 2004-03-17 | Koninklijke Philips Electronics N.V. | Metal-ceramic bond |
IL160080A0 (en) * | 2001-08-31 | 2004-06-20 | Thomson Licensing Sa | Sequence counter for an audio visual stream |
US20050187191A1 (en) * | 2004-02-20 | 2005-08-25 | Kucera Louis S. | Methods and compositions for the treatment of respiratory syncytial virus |
US20080187487A1 (en) * | 2006-05-03 | 2008-08-07 | Gustavo Larsen | Methods for producing multilayered particles, fibers and sprays and methods for administering the same |
EP1869981A1 (de) * | 2006-06-21 | 2007-12-26 | Staatliches Weinbauinstitut Freiburg | Alkylphospholipide und Lyso-Phospholipide zur Bekämpfung von Pflanzenpathogenen |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4159988A (en) | 1974-08-06 | 1979-07-03 | Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. | Synthetic phospholipids, a process for their manufacture and their use |
DE2619686C2 (de) * | 1976-05-04 | 1986-08-07 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V., 3400 Göttingen | Verwendung eines Lysolecithins zur Tumorbehandlung |
DE2619715A1 (de) | 1976-05-04 | 1977-11-24 | Max Planck Gesellschaft | Tumor-antigen und verfahren zu dessen herstellung |
-
1980
- 1980-10-22 JP JP55148485A patent/JPS5772914A/ja active Pending
-
1981
- 1981-10-12 EP EP81304732A patent/EP0050460B1/en not_active Expired
- 1981-10-12 DE DE8181304732T patent/DE3171325D1/de not_active Expired
- 1981-10-15 US US06/311,876 patent/US4426525A/en not_active Expired - Fee Related
- 1981-10-21 CA CA000388394A patent/CA1176254A/en not_active Expired
-
1983
- 1983-12-09 US US06/559,634 patent/US4544512A/en not_active Expired - Fee Related
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5829794A (ja) * | 1981-07-31 | 1983-02-22 | Fujisawa Pharmaceut Co Ltd | 燐脂質誘導体 |
JPH0368877B2 (ja) * | 1981-07-31 | 1991-10-30 | Fujisawa Pharmaceutical Co |
Also Published As
Publication number | Publication date |
---|---|
EP0050460A2 (en) | 1982-04-28 |
US4426525A (en) | 1984-01-17 |
US4544512A (en) | 1985-10-01 |
DE3171325D1 (en) | 1985-08-14 |
CA1176254A (en) | 1984-10-16 |
EP0050460A3 (en) | 1982-10-27 |
EP0050460B1 (en) | 1985-07-10 |
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