JPS5759881A - 1alpha,25-dihydroxyvitamin d3-26,23-lactone - Google Patents
1alpha,25-dihydroxyvitamin d3-26,23-lactoneInfo
- Publication number
- JPS5759881A JPS5759881A JP13527680A JP13527680A JPS5759881A JP S5759881 A JPS5759881 A JP S5759881A JP 13527680 A JP13527680 A JP 13527680A JP 13527680 A JP13527680 A JP 13527680A JP S5759881 A JPS5759881 A JP S5759881A
- Authority
- JP
- Japan
- Prior art keywords
- dihydroxyvitamin
- lactone
- dogs
- rats
- 1alpha
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- WMYIVSWWSRCZFA-RWVJFQLJSA-N 1,25-Dihydroxyvitamin D3-26,23-lactone Chemical compound C([C@@H](C)[C@@H]1[C@]2(CCCC(/[C@@H]2CC1)=C\C=C\1C([C@@H](O)C[C@H](O)C/1)=C)C)[C@H]1C[C@@](C)(O)C(=O)O1 WMYIVSWWSRCZFA-RWVJFQLJSA-N 0.000 title abstract 2
- 241000282472 Canis lupus familiaris Species 0.000 abstract 2
- 241000700159 Rattus Species 0.000 abstract 2
- OFHCOWSQAMBJIW-AVJTYSNKSA-N alfacalcidol Chemical compound C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C\C=C1\C[C@@H](O)C[C@H](O)C1=C OFHCOWSQAMBJIW-AVJTYSNKSA-N 0.000 abstract 1
- 239000011612 calcitriol Substances 0.000 abstract 1
- GMRQFYUYWCNGIN-NKMMMXOESA-N calcitriol Chemical compound C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@@H](CCCC(C)(C)O)C)=C\C=C1\C[C@@H](O)C[C@H](O)C1=C GMRQFYUYWCNGIN-NKMMMXOESA-N 0.000 abstract 1
- 238000004440 column chromatography Methods 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- 238000004811 liquid chromatography Methods 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 239000002207 metabolite Substances 0.000 abstract 1
- 239000011647 vitamin D3 Substances 0.000 abstract 1
- QYSXJUFSXHHAJI-YRZJJWOYSA-N vitamin D3 Chemical compound C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C\C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-YRZJJWOYSA-N 0.000 abstract 1
Landscapes
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Furan Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP13527680A JPS5759881A (en) | 1980-09-30 | 1980-09-30 | 1alpha,25-dihydroxyvitamin d3-26,23-lactone |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP13527680A JPS5759881A (en) | 1980-09-30 | 1980-09-30 | 1alpha,25-dihydroxyvitamin d3-26,23-lactone |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS5759881A true JPS5759881A (en) | 1982-04-10 |
| JPS6140231B2 JPS6140231B2 (enExample) | 1986-09-08 |
Family
ID=15147916
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP13527680A Granted JPS5759881A (en) | 1980-09-30 | 1980-09-30 | 1alpha,25-dihydroxyvitamin d3-26,23-lactone |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS5759881A (enExample) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS59148775A (ja) * | 1983-02-14 | 1984-08-25 | Teijin Ltd | ２５―ヒドロキシビタミンｄ３―２６，２３―ラクトン誘導体 |
| US4632784A (en) * | 1983-01-28 | 1986-12-30 | Hoffmann-La Roche Inc. | Process for the preparation of 1α,23,25-trihydroxycholecalciferol-26-oic acid 23,26-lactone |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0531861A (ja) * | 1991-07-26 | 1993-02-09 | Sumitomo Bakelite Co Ltd | 密封容器 |
-
1980
- 1980-09-30 JP JP13527680A patent/JPS5759881A/ja active Granted
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4632784A (en) * | 1983-01-28 | 1986-12-30 | Hoffmann-La Roche Inc. | Process for the preparation of 1α,23,25-trihydroxycholecalciferol-26-oic acid 23,26-lactone |
| JPS59148775A (ja) * | 1983-02-14 | 1984-08-25 | Teijin Ltd | ２５―ヒドロキシビタミンｄ３―２６，２３―ラクトン誘導体 |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6140231B2 (enExample) | 1986-09-08 |
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