JPS5759847A - 4-aminomethylcyclohexanecarboxylic acid derivative - Google Patents
4-aminomethylcyclohexanecarboxylic acid derivativeInfo
- Publication number
- JPS5759847A JPS5759847A JP13700880A JP13700880A JPS5759847A JP S5759847 A JPS5759847 A JP S5759847A JP 13700880 A JP13700880 A JP 13700880A JP 13700880 A JP13700880 A JP 13700880A JP S5759847 A JPS5759847 A JP S5759847A
- Authority
- JP
- Japan
- Prior art keywords
- compound expressed
- formula
- trans
- agent
- acid derivative
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- GYDJEQRTZSCIOI-UHFFFAOYSA-N Tranexamic acid Chemical class NCC1CCC(C(O)=O)CC1 GYDJEQRTZSCIOI-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 4
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 abstract 3
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- NZNMSOFKMUBTKW-UHFFFAOYSA-N cyclohexanecarboxylic acid Chemical compound OC(=O)C1CCCCC1 NZNMSOFKMUBTKW-UHFFFAOYSA-N 0.000 abstract 2
- NGNBDVOYPDDBFK-UHFFFAOYSA-N 2-[2,4-di(pentan-2-yl)phenoxy]acetyl chloride Chemical compound CCCC(C)C1=CC=C(OCC(Cl)=O)C(C(C)CCC)=C1 NGNBDVOYPDDBFK-UHFFFAOYSA-N 0.000 abstract 1
- 208000023275 Autoimmune disease Diseases 0.000 abstract 1
- 208000027932 Collagen disease Diseases 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 208000026935 allergic disease Diseases 0.000 abstract 1
- 150000008064 anhydrides Chemical class 0.000 abstract 1
- 230000002785 anti-thrombosis Effects 0.000 abstract 1
- 230000000259 anti-tumor effect Effects 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- VZFUCHSFHOYXIS-UHFFFAOYSA-N cycloheptane carboxylic acid Natural products OC(=O)C1CCCCCC1 VZFUCHSFHOYXIS-UHFFFAOYSA-N 0.000 abstract 1
- 239000012024 dehydrating agents Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 201000008383 nephritis Diseases 0.000 abstract 1
- 238000010992 reflux Methods 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Landscapes
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP13700880A JPS5759847A (en) | 1980-09-29 | 1980-09-29 | 4-aminomethylcyclohexanecarboxylic acid derivative |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP13700880A JPS5759847A (en) | 1980-09-29 | 1980-09-29 | 4-aminomethylcyclohexanecarboxylic acid derivative |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS5759847A true JPS5759847A (en) | 1982-04-10 |
| JPS648616B2 JPS648616B2 (en, 2012) | 1989-02-14 |
Family
ID=15188646
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP13700880A Granted JPS5759847A (en) | 1980-09-29 | 1980-09-29 | 4-aminomethylcyclohexanecarboxylic acid derivative |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS5759847A (en, 2012) |
Cited By (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6169816A (ja) * | 1984-09-13 | 1986-04-10 | Mitsubishi Chem Ind Ltd | 多孔質共重合体の製造方法 |
| EP0585130A3 (en) * | 1992-08-27 | 1994-06-08 | Shiseido Co Ltd | External preparation for skin containing a depigmentation agent |
| EP0647616A4 (en) * | 1992-06-23 | 1995-08-16 | Zaidan Hojin Seisan Kaihatsu K | ZINC TRANEXAMATE DERIVATIVE. |
| EP1132083A3 (en) * | 2000-03-08 | 2002-10-23 | Hamari Chemicals Co., Ltd. | Use of zinc tranexamate in the treatment of diabetes |
| WO2005011650A1 (en) * | 2003-07-31 | 2005-02-10 | Xanodyne Pharmaceuticals, Inc. | Tranexamic acid formulations with reduced adverse effects |
| US7947739B2 (en) | 2004-03-04 | 2011-05-24 | Ferring B.V. | Tranexamic acid formulations |
| US8487005B2 (en) | 2004-03-04 | 2013-07-16 | Ferring B.V. | Tranexamic acid formulations |
| US8957113B2 (en) | 2004-03-04 | 2015-02-17 | Ferring B.V. | Tranexamic acid formulations |
| CN108976146A (zh) * | 2017-05-31 | 2018-12-11 | 首都医科大学 | 氨基正己酰氨甲环酰氨基正己酰芳香氨基酸，其合成，活性和应用 |
| CN109081790A (zh) * | 2017-06-13 | 2018-12-25 | 首都医科大学 | 氨基正己酰氨基甲环酰氨基正己酰碱性氨基酸，其合成，活性和应用 |
| CN117603080A (zh) * | 2023-10-26 | 2024-02-27 | 常州寅盛药业有限公司 | 一种氨甲环酸杂质的制备方法 |
-
1980
- 1980-09-29 JP JP13700880A patent/JPS5759847A/ja active Granted
Cited By (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6169816A (ja) * | 1984-09-13 | 1986-04-10 | Mitsubishi Chem Ind Ltd | 多孔質共重合体の製造方法 |
| EP0647616A4 (en) * | 1992-06-23 | 1995-08-16 | Zaidan Hojin Seisan Kaihatsu K | ZINC TRANEXAMATE DERIVATIVE. |
| US5506264A (en) * | 1992-06-23 | 1996-04-09 | Zaidan Hojin Seisan Kaihatsu Kaguki Kenkyusho | Zinc tranexamate compounds |
| EP0585130A3 (en) * | 1992-08-27 | 1994-06-08 | Shiseido Co Ltd | External preparation for skin containing a depigmentation agent |
| US5690914A (en) * | 1992-08-27 | 1997-11-25 | Shiseido Co., Ltd | External preparation for skin |
| EP1132083A3 (en) * | 2000-03-08 | 2002-10-23 | Hamari Chemicals Co., Ltd. | Use of zinc tranexamate in the treatment of diabetes |
| US8968777B2 (en) | 2003-07-31 | 2015-03-03 | Ferring B.V. | Tranexamic acid formulations with reduced adverse effects |
| WO2005011650A1 (en) * | 2003-07-31 | 2005-02-10 | Xanodyne Pharmaceuticals, Inc. | Tranexamic acid formulations with reduced adverse effects |
| US7947739B2 (en) | 2004-03-04 | 2011-05-24 | Ferring B.V. | Tranexamic acid formulations |
| US8487005B2 (en) | 2004-03-04 | 2013-07-16 | Ferring B.V. | Tranexamic acid formulations |
| US8791160B2 (en) | 2004-03-04 | 2014-07-29 | Ferring B.V. | Tranexamic acid formulations |
| US8809394B2 (en) | 2004-03-04 | 2014-08-19 | Ferring B.V. | Tranexamic acid formulations |
| US8957113B2 (en) | 2004-03-04 | 2015-02-17 | Ferring B.V. | Tranexamic acid formulations |
| US9060939B2 (en) | 2004-03-04 | 2015-06-23 | Ferring B.V. | Tranexamic acid formulations |
| CN108976146A (zh) * | 2017-05-31 | 2018-12-11 | 首都医科大学 | 氨基正己酰氨甲环酰氨基正己酰芳香氨基酸，其合成，活性和应用 |
| CN108976146B (zh) * | 2017-05-31 | 2020-11-27 | 首都医科大学 | 氨基正己酰氨甲环酰氨基正己酰芳香氨基酸，其合成，活性和应用 |
| CN109081790A (zh) * | 2017-06-13 | 2018-12-25 | 首都医科大学 | 氨基正己酰氨基甲环酰氨基正己酰碱性氨基酸，其合成，活性和应用 |
| CN109081790B (zh) * | 2017-06-13 | 2021-02-12 | 首都医科大学 | 氨基正己酰氨基甲环酰氨基正己酰碱性氨基酸，其合成，活性和应用 |
| CN117603080A (zh) * | 2023-10-26 | 2024-02-27 | 常州寅盛药业有限公司 | 一种氨甲环酸杂质的制备方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS648616B2 (en, 2012) | 1989-02-14 |
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