JPS5756454A - Disulfide type cysteine derivative - Google Patents
Disulfide type cysteine derivativeInfo
- Publication number
- JPS5756454A JPS5756454A JP55131349A JP13134980A JPS5756454A JP S5756454 A JPS5756454 A JP S5756454A JP 55131349 A JP55131349 A JP 55131349A JP 13134980 A JP13134980 A JP 13134980A JP S5756454 A JPS5756454 A JP S5756454A
- Authority
- JP
- Japan
- Prior art keywords
- compound shown
- formula
- formulai
- residue
- cysteine derivative
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- BWGNESOTFCXPMA-UHFFFAOYSA-N Dihydrogen disulfide Chemical compound SS BWGNESOTFCXPMA-UHFFFAOYSA-N 0.000 title 1
- 150000001944 cysteine derivatives Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 4
- 208000002177 Cataract Diseases 0.000 abstract 1
- 239000004201 L-cysteine Substances 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000008065 acid anhydrides Chemical class 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 230000003356 anti-rheumatic effect Effects 0.000 abstract 1
- 239000003435 antirheumatic agent Substances 0.000 abstract 1
- 125000003435 aroyl group Chemical group 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 125000001589 carboacyl group Chemical group 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- -1 disulfide compound Chemical class 0.000 abstract 1
- 150000004820 halides Chemical class 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 208000019423 liver disease Diseases 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 239000007800 oxidant agent Substances 0.000 abstract 1
- 125000001325 propanoyl group Chemical group O=C([*])C([H])([H])C([H])([H])[H] 0.000 abstract 1
- 230000001105 regulatory effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
- C07C319/14—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides
- C07C319/20—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides by reactions not involving the formation of sulfide groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
- C07C319/02—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of thiols
- C07C319/12—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of thiols by reactions not involving the formation of mercapto groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/60—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton with the carbon atom of at least one of the carboxyl groups bound to nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/12—Ophthalmic agents for cataracts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C321/00—Thiols, sulfides, hydropolysulfides or polysulfides
- C07C321/12—Sulfides, hydropolysulfides, or polysulfides having thio groups bound to acyclic carbon atoms
- C07C321/14—Sulfides, hydropolysulfides, or polysulfides having thio groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
- C07D285/36—Seven-membered rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Ophthalmology & Optometry (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Gastroenterology & Hepatology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
Priority Applications (13)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP55131349A JPS5756454A (en) | 1980-09-20 | 1980-09-20 | Disulfide type cysteine derivative |
| GB8214992A GB2096145B (en) | 1980-09-20 | 1981-09-18 | Disulfide type cysteine derivatives |
| BE2/59362A BE890399A (fr) | 1980-09-20 | 1981-09-18 | Bisulfures intra- ou intermoleculaires de derives de cysteine |
| DE19813152362 DE3152362C2 (de) | 1980-09-20 | 1981-09-18 | Cyclische Disulfide von N-Mercaptoacyl-cystein-Derivaten, Verfahren zu deren Herstellung und diese enthaltende Arzneimittel |
| ES505628A ES505628A0 (es) | 1980-09-20 | 1981-09-18 | Un procedimiento para la fabricacion de un disulfuro intra ointermolecular |
| CA000386241A CA1162188A (en) | 1980-09-20 | 1981-09-18 | Intra-or intermolecular disulfide of cysteine derivatives |
| PCT/JP1981/000235 WO1982001000A1 (en) | 1980-09-20 | 1981-09-18 | Disulfide type cysteine derivatives |
| AU75900/81A AU7590081A (en) | 1980-09-20 | 1981-09-18 | Disulfide type cysteine derivatives |
| US06/380,665 US4517123A (en) | 1980-09-20 | 1981-09-18 | Cysteine derivatives of disulfide form |
| KR1019810003505A KR880000041B1 (ko) | 1980-09-20 | 1981-09-19 | 시스테인 유동체의 분자내 또는 분자간 이황화물의 제조방법 |
| FR8117808A FR2490637A1 (fr) | 1980-09-20 | 1981-09-21 | Nouveaux disulfures intra- ou intermoleculaires de derives de cysteine utiles comme medicaments et procedes pour leur preparation |
| IT24057/81A IT1138226B (it) | 1980-09-20 | 1981-09-21 | Disolfuro intra-o intermolecolare di derivati di cisteina |
| SE8203053A SE447379B (sv) | 1980-09-20 | 1982-05-14 | Vissa disulfider |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP55131349A JPS5756454A (en) | 1980-09-20 | 1980-09-20 | Disulfide type cysteine derivative |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS5756454A true JPS5756454A (en) | 1982-04-05 |
| JPS6143350B2 JPS6143350B2 (en, 2012) | 1986-09-26 |
Family
ID=15055849
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP55131349A Granted JPS5756454A (en) | 1980-09-20 | 1980-09-20 | Disulfide type cysteine derivative |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US4517123A (en, 2012) |
| JP (1) | JPS5756454A (en, 2012) |
| KR (1) | KR880000041B1 (en, 2012) |
| AU (1) | AU7590081A (en, 2012) |
| BE (1) | BE890399A (en, 2012) |
| CA (1) | CA1162188A (en, 2012) |
| DE (1) | DE3152362C2 (en, 2012) |
| ES (1) | ES505628A0 (en, 2012) |
| FR (1) | FR2490637A1 (en, 2012) |
| GB (1) | GB2096145B (en, 2012) |
| IT (1) | IT1138226B (en, 2012) |
| SE (1) | SE447379B (en, 2012) |
| WO (1) | WO1982001000A1 (en, 2012) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH03176465A (ja) * | 1989-12-05 | 1991-07-31 | Santen Pharmaceut Co Ltd | 含硫黄アミノ酸誘導体 |
| US5081307A (en) * | 1989-07-14 | 1992-01-14 | Kawaguchi Chemical Co., Ltd. | Process for preparing 2,2-dimethoxy-2-phenylacetophenone |
| WO1994003167A1 (en) * | 1992-08-01 | 1994-02-17 | Santen Pharmaceutical Co., Ltd. | Cataract remedy |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0326326B1 (en) * | 1988-01-25 | 1993-01-07 | Santen Pharmaceutical Co., Ltd. | Cysteine derivatives |
| US5041435A (en) * | 1988-08-13 | 1991-08-20 | Santen Pharmaceutical Co., Ltd. | Cyclic sulfur-containing compounds |
| US5175256A (en) * | 1990-09-28 | 1992-12-29 | Neorx Corporation | Protein labeling reagents |
| US5670545A (en) * | 1996-02-09 | 1997-09-23 | Board Of Regents Of The University Of Colorado | Method for the treatment of ischemic disease and reperfusion injury and the prevention of the adverse effects of reactive oxygen species |
| US10655227B2 (en) | 2017-10-06 | 2020-05-19 | Rohm And Haas Electronic Materials Llc | Stable electroless copper plating compositions and methods for electroless plating copper on substrates |
| US10294569B2 (en) | 2017-10-06 | 2019-05-21 | Rohm And Haas Electronic Materials Llc | Stable electroless copper plating compositions and methods for electroless plating copper on substrates |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5271928A (en) * | 1975-12-11 | 1977-06-15 | Sony Corp | Receiving and recording unit of tv signals |
| JPS535112A (en) * | 1976-03-08 | 1978-01-18 | Santen Pharmaceutical Co Ltd | New cysteine derivatives |
| JPS545916A (en) * | 1977-06-17 | 1979-01-17 | Santen Pharmaceutical Co Ltd | Novel cystein derivative |
| JPS6058908B2 (ja) * | 1978-10-11 | 1985-12-23 | 参天製薬株式会社 | システイン誘導体 |
| JPS6011888B2 (ja) * | 1978-10-11 | 1985-03-28 | 参天製薬株式会社 | リウマチ疾患治療薬 |
-
1980
- 1980-09-20 JP JP55131349A patent/JPS5756454A/ja active Granted
-
1981
- 1981-09-18 US US06/380,665 patent/US4517123A/en not_active Expired - Lifetime
- 1981-09-18 AU AU75900/81A patent/AU7590081A/en not_active Abandoned
- 1981-09-18 GB GB8214992A patent/GB2096145B/en not_active Expired
- 1981-09-18 WO PCT/JP1981/000235 patent/WO1982001000A1/ja active Application Filing
- 1981-09-18 CA CA000386241A patent/CA1162188A/en not_active Expired
- 1981-09-18 DE DE19813152362 patent/DE3152362C2/de not_active Expired
- 1981-09-18 BE BE2/59362A patent/BE890399A/fr not_active IP Right Cessation
- 1981-09-18 ES ES505628A patent/ES505628A0/es active Granted
- 1981-09-19 KR KR1019810003505A patent/KR880000041B1/ko not_active Expired
- 1981-09-21 IT IT24057/81A patent/IT1138226B/it active
- 1981-09-21 FR FR8117808A patent/FR2490637A1/fr active Granted
-
1982
- 1982-05-14 SE SE8203053A patent/SE447379B/sv not_active IP Right Cessation
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5081307A (en) * | 1989-07-14 | 1992-01-14 | Kawaguchi Chemical Co., Ltd. | Process for preparing 2,2-dimethoxy-2-phenylacetophenone |
| JPH03176465A (ja) * | 1989-12-05 | 1991-07-31 | Santen Pharmaceut Co Ltd | 含硫黄アミノ酸誘導体 |
| WO1994003167A1 (en) * | 1992-08-01 | 1994-02-17 | Santen Pharmaceutical Co., Ltd. | Cataract remedy |
Also Published As
| Publication number | Publication date |
|---|---|
| US4517123A (en) | 1985-05-14 |
| GB2096145B (en) | 1984-05-02 |
| JPS6143350B2 (en, 2012) | 1986-09-26 |
| IT8124057A0 (it) | 1981-09-21 |
| CA1162188A (en) | 1984-02-14 |
| GB2096145A (en) | 1982-10-13 |
| BE890399A (fr) | 1982-01-18 |
| DE3152362C2 (de) | 1986-08-28 |
| AU7590081A (en) | 1982-04-14 |
| IT1138226B (it) | 1986-09-17 |
| KR880000041B1 (ko) | 1988-02-20 |
| SE8203053L (sv) | 1982-05-14 |
| ES8303316A1 (es) | 1983-02-01 |
| FR2490637A1 (fr) | 1982-03-26 |
| WO1982001000A1 (en) | 1982-04-01 |
| SE447379B (sv) | 1986-11-10 |
| DE3152362T1 (en, 2012) | 1982-10-07 |
| KR830007539A (ko) | 1983-10-21 |
| ES505628A0 (es) | 1983-02-01 |
| FR2490637B1 (en, 2012) | 1984-12-14 |
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