JPS5748935A - Preparation of 2-substituted cycloalkanone - Google Patents

Preparation of 2-substituted cycloalkanone

Info

Publication number
JPS5748935A
JPS5748935A JP12554980A JP12554980A JPS5748935A JP S5748935 A JPS5748935 A JP S5748935A JP 12554980 A JP12554980 A JP 12554980A JP 12554980 A JP12554980 A JP 12554980A JP S5748935 A JPS5748935 A JP S5748935A
Authority
JP
Japan
Prior art keywords
water
formula
soluble amine
enamine
cycloalkanone
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP12554980A
Other languages
Japanese (ja)
Other versions
JPS6338013B2 (en
Inventor
Junji Kawashima
Kuniaki Goto
Akinobu Osawa
Shinichi Hirakawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zeon Corp
Original Assignee
Nippon Zeon Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nippon Zeon Co Ltd filed Critical Nippon Zeon Co Ltd
Priority to JP12554980A priority Critical patent/JPS5748935A/en
Publication of JPS5748935A publication Critical patent/JPS5748935A/en
Publication of JPS6338013B2 publication Critical patent/JPS6338013B2/ja
Granted legal-status Critical Current

Links

Abstract

PURPOSE: To prepare the titled substance by condensing an enamine derived from a cycloalkanone and a water-soluble amine with an aldehyde, heating and hydrolyzing the resulted 2-substituted enamine in the presence of water, and purifying and recycling the water-soluble amine obtained as a by-product.
CONSTITUTION: A cycloalkanone of formula I (n is integer 2W9) is made to react with a water-soluble amine of formula III (R2 is secondary amino residue) using a dehydration catalyst in the presence of a water-insoluble solvent capable of forming an azeotropic mixture with water to obtain the enamine of formula IV, which is condensed with an aldehyde of formula V (R1 is hydrocarbon residue) to afford the 2- substituted enamine of formula VI. The compound is hydrolyzed to the 2-substituted cycloalkanone of formula II and the water-soluble amine of formula III by heating in the presence of water, and the reaction product is separated into the organic phase and the aqueous phase. The water-soluble amine extracted to the aqueous phase is recycled to the first step, and the organic phase is purified to obtain the objective compound of formula II.
COPYRIGHT: (C)1982,JPO&Japio
JP12554980A 1980-09-10 1980-09-10 Preparation of 2-substituted cycloalkanone Granted JPS5748935A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP12554980A JPS5748935A (en) 1980-09-10 1980-09-10 Preparation of 2-substituted cycloalkanone

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP12554980A JPS5748935A (en) 1980-09-10 1980-09-10 Preparation of 2-substituted cycloalkanone

Publications (2)

Publication Number Publication Date
JPS5748935A true JPS5748935A (en) 1982-03-20
JPS6338013B2 JPS6338013B2 (en) 1988-07-28

Family

ID=14912946

Family Applications (1)

Application Number Title Priority Date Filing Date
JP12554980A Granted JPS5748935A (en) 1980-09-10 1980-09-10 Preparation of 2-substituted cycloalkanone

Country Status (1)

Country Link
JP (1) JPS5748935A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60228444A (en) * 1984-04-27 1985-11-13 Nippon Zeon Co Ltd Preparation of substituent group-containing alicyclic enamine

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5040540A (en) * 1973-05-24 1975-04-14

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5040540A (en) * 1973-05-24 1975-04-14

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60228444A (en) * 1984-04-27 1985-11-13 Nippon Zeon Co Ltd Preparation of substituent group-containing alicyclic enamine
JPH0219817B2 (en) * 1984-04-27 1990-05-07 Nippon Zeon Co

Also Published As

Publication number Publication date
JPS6338013B2 (en) 1988-07-28

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