JPS5742697A - Mycinamicin derivative - Google Patents

Mycinamicin derivative

Info

Publication number
JPS5742697A
JPS5742697A JP11807980A JP11807980A JPS5742697A JP S5742697 A JPS5742697 A JP S5742697A JP 11807980 A JP11807980 A JP 11807980A JP 11807980 A JP11807980 A JP 11807980A JP S5742697 A JPS5742697 A JP S5742697A
Authority
JP
Japan
Prior art keywords
formula
compound
mycinamicin
chloroform
gram
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP11807980A
Other languages
Japanese (ja)
Other versions
JPS634826B2 (en
Inventor
Mitsuo Hayashi
Kenji Kinoshita
Masaru Ono
Shuzo Satoi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Toyo Jozo KK
Original Assignee
Toyo Jozo KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toyo Jozo KK filed Critical Toyo Jozo KK
Priority to JP11807980A priority Critical patent/JPS5742697A/en
Publication of JPS5742697A publication Critical patent/JPS5742697A/en
Publication of JPS634826B2 publication Critical patent/JPS634826B2/ja
Granted legal-status Critical Current

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  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:The compound of formula I (R1 is H or hydroxy; R2 is H or desosaminyl group of formula II; R3 is H or mycinosyl group of formula III; at least one of R2 and R3 is H).
EXAMPLE: Demycinosylmycinamicin IV.
USE: The compound has anti-microbial activity against Gram-positive bacteria, Gram- negative bacteria, and micoplasma, and is useful as a remedy and preventive for diseases of animals, a feed additive, etc.
PROCESS: For example, mycinamicin IV is dissolved in dilute hydrochloric acid, and hydrolyzed by heating. The reaction liquid is cooled, controlled to basic with concentrated aqueous ammonia, and extracted with chloroform, etc. The chloroform layer is washed with water, dehydrated, and dried under reduced pressure. The residue is purified by column chromatography using silica gel as adsorbent to obtain the objective compound of formula I.
COPYRIGHT: (C)1982,JPO&Japio
JP11807980A 1980-08-26 1980-08-26 Mycinamicin derivative Granted JPS5742697A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP11807980A JPS5742697A (en) 1980-08-26 1980-08-26 Mycinamicin derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP11807980A JPS5742697A (en) 1980-08-26 1980-08-26 Mycinamicin derivative

Publications (2)

Publication Number Publication Date
JPS5742697A true JPS5742697A (en) 1982-03-10
JPS634826B2 JPS634826B2 (en) 1988-02-01

Family

ID=14727469

Family Applications (1)

Application Number Title Priority Date Filing Date
JP11807980A Granted JPS5742697A (en) 1980-08-26 1980-08-26 Mycinamicin derivative

Country Status (1)

Country Link
JP (1) JPS5742697A (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS591419A (en) * 1982-06-22 1984-01-06 Toyo Jozo Co Ltd Carrier containing antibiotic substance
JPS60120815A (en) * 1983-12-01 1985-06-28 Toyo Jozo Co Ltd Composition for animal use
US4626547A (en) * 1982-01-21 1986-12-02 The Kitasato Institute Antibiotic AM-2604-A, an anti-trichomonas agent, anti-caccidium agent, anti-viral agent and anti-fungal agent containing the same and methods of use of the same
US4794173A (en) * 1985-05-13 1988-12-27 Yamanouchi Pharmaceutical Co., Ltd. Mycaminosyl tylonolide derivatives

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4626547A (en) * 1982-01-21 1986-12-02 The Kitasato Institute Antibiotic AM-2604-A, an anti-trichomonas agent, anti-caccidium agent, anti-viral agent and anti-fungal agent containing the same and methods of use of the same
JPS591419A (en) * 1982-06-22 1984-01-06 Toyo Jozo Co Ltd Carrier containing antibiotic substance
JPH0136810B2 (en) * 1982-06-22 1989-08-02 Toyo Jozo Kk
JPS60120815A (en) * 1983-12-01 1985-06-28 Toyo Jozo Co Ltd Composition for animal use
US4794173A (en) * 1985-05-13 1988-12-27 Yamanouchi Pharmaceutical Co., Ltd. Mycaminosyl tylonolide derivatives
US4914192A (en) * 1985-05-13 1990-04-03 Yamanouchi Pharmaceutical Co., Ltd. Mycaminosyl tylonolide derivatives
US4945081A (en) * 1985-05-13 1990-07-31 Yamanouchi Pharmaceutical Co., Ltd. Mycaminosyl tylonolide derivatives
US5101022A (en) * 1985-05-13 1992-03-31 Yamanouchi Pharmaceutical Co., Ltd. Mycaminosyl tylonolide derivatives

Also Published As

Publication number Publication date
JPS634826B2 (en) 1988-02-01

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