JPS5735591A - Novel pyrimidine derivative - Google Patents
Novel pyrimidine derivativeInfo
- Publication number
- JPS5735591A JPS5735591A JP11070880A JP11070880A JPS5735591A JP S5735591 A JPS5735591 A JP S5735591A JP 11070880 A JP11070880 A JP 11070880A JP 11070880 A JP11070880 A JP 11070880A JP S5735591 A JPS5735591 A JP S5735591A
- Authority
- JP
- Japan
- Prior art keywords
- diethylamino
- nitropyrimidine
- methyl
- formula
- amino group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000003230 pyrimidines Chemical class 0.000 title 1
- 230000000694 effects Effects 0.000 abstract 3
- -1 7-Diethylamino-5-methyloxazolo[5,4-d]pyrimidine Chemical compound 0.000 abstract 2
- 125000003277 amino group Chemical group 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- BDAGIHXWWSANSR-UHFFFAOYSA-N methanoic acid Natural products OC=O BDAGIHXWWSANSR-UHFFFAOYSA-N 0.000 abstract 2
- 238000007363 ring formation reaction Methods 0.000 abstract 2
- OSWFIVFLDKOXQC-UHFFFAOYSA-N 4-(3-methoxyphenyl)aniline Chemical compound COC1=CC=CC(C=2C=CC(N)=CC=2)=C1 OSWFIVFLDKOXQC-UHFFFAOYSA-N 0.000 abstract 1
- QHQKMWVMJBCEBM-UHFFFAOYSA-N 6-(diethylamino)-2-methyl-5-nitro-1h-pyrimidine-4-thione Chemical compound CCN(CC)C1=NC(C)=NC(S)=C1[N+]([O-])=O QHQKMWVMJBCEBM-UHFFFAOYSA-N 0.000 abstract 1
- 208000001953 Hypotension Diseases 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 150000005005 aminopyrimidines Chemical class 0.000 abstract 1
- 210000001772 blood platelet Anatomy 0.000 abstract 1
- 210000000748 cardiovascular system Anatomy 0.000 abstract 1
- 230000015271 coagulation Effects 0.000 abstract 1
- 238000005345 coagulation Methods 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 235000019253 formic acid Nutrition 0.000 abstract 1
- 230000022244 formylation Effects 0.000 abstract 1
- 238000006170 formylation reaction Methods 0.000 abstract 1
- 208000021822 hypotensive Diseases 0.000 abstract 1
- 230000001077 hypotensive effect Effects 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- FAIAAWCVCHQXDN-UHFFFAOYSA-N phosphorus trichloride Chemical compound ClP(Cl)Cl FAIAAWCVCHQXDN-UHFFFAOYSA-N 0.000 abstract 1
- XHXFXVLFKHQFAL-UHFFFAOYSA-N phosphoryl trichloride Chemical compound ClP(Cl)(Cl)=O XHXFXVLFKHQFAL-UHFFFAOYSA-N 0.000 abstract 1
- 230000000304 vasodilatating effect Effects 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Landscapes
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP11070880A JPS5735591A (en) | 1980-08-12 | 1980-08-12 | Novel pyrimidine derivative |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP11070880A JPS5735591A (en) | 1980-08-12 | 1980-08-12 | Novel pyrimidine derivative |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS5735591A true JPS5735591A (en) | 1982-02-26 |
| JPS6346756B2 JPS6346756B2 (enrdf_load_stackoverflow) | 1988-09-19 |
Family
ID=14542441
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP11070880A Granted JPS5735591A (en) | 1980-08-12 | 1980-08-12 | Novel pyrimidine derivative |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS5735591A (enrdf_load_stackoverflow) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4476127A (en) * | 1982-02-19 | 1984-10-09 | Mochida Pharmaceutical Co., Ltd. | 7-Diethylamino-5-methyl-thiazolo[5,4-d]pyrimidine and pharmaceutical composition containing same |
| DE4003388A1 (de) * | 1989-02-06 | 1990-08-16 | Fuji Electric Co Ltd | Mos halbleitervorrichtung |
| US5115287A (en) * | 1986-11-19 | 1992-05-19 | Research Development Corporation Of Japan | Step-cut insulated gate static induction transistors and method of manufacturing the same |
| US5300509A (en) * | 1991-11-25 | 1994-04-05 | Imperial Chemical Industries Plc | 2-furyl-oxazolo[5,4-d]-pyrimidines |
-
1980
- 1980-08-12 JP JP11070880A patent/JPS5735591A/ja active Granted
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4476127A (en) * | 1982-02-19 | 1984-10-09 | Mochida Pharmaceutical Co., Ltd. | 7-Diethylamino-5-methyl-thiazolo[5,4-d]pyrimidine and pharmaceutical composition containing same |
| US5115287A (en) * | 1986-11-19 | 1992-05-19 | Research Development Corporation Of Japan | Step-cut insulated gate static induction transistors and method of manufacturing the same |
| DE4003388A1 (de) * | 1989-02-06 | 1990-08-16 | Fuji Electric Co Ltd | Mos halbleitervorrichtung |
| US5021846A (en) * | 1989-02-06 | 1991-06-04 | Fuji Electric Co., Ltd. | MOS semiconductor device with an inverted U-shaped gate |
| US5300509A (en) * | 1991-11-25 | 1994-04-05 | Imperial Chemical Industries Plc | 2-furyl-oxazolo[5,4-d]-pyrimidines |
| US5500428A (en) * | 1991-11-25 | 1996-03-19 | Imperial Chemical Industries Plc | Furyl-substituted purines and adenosine antagonists |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6346756B2 (enrdf_load_stackoverflow) | 1988-09-19 |
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