JPS5735518A - Cremastosine 1 and/or cremastosine 2 - Google Patents

Cremastosine 1 and/or cremastosine 2

Info

Publication number
JPS5735518A
JPS5735518A JP11073080A JP11073080A JPS5735518A JP S5735518 A JPS5735518 A JP S5735518A JP 11073080 A JP11073080 A JP 11073080A JP 11073080 A JP11073080 A JP 11073080A JP S5735518 A JPS5735518 A JP S5735518A
Authority
JP
Japan
Prior art keywords
soluble
cremastosine
water
easily soluble
state
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP11073080A
Other languages
Japanese (ja)
Inventor
Fumio Shibayama
Yoshiyasu Koma
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fujisawa Pharmaceutical Co Ltd
Original Assignee
Fujisawa Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujisawa Pharmaceutical Co Ltd filed Critical Fujisawa Pharmaceutical Co Ltd
Priority to JP11073080A priority Critical patent/JPS5735518A/en
Publication of JPS5735518A publication Critical patent/JPS5735518A/en
Pending legal-status Critical Current

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Abstract

NEW MATERIAL:Cremastosine I. Appearance: colorless thin needlelike crystal. Melting point: 208W221°C. Solubility: soluble in water and methanol under cold state and easily soluble in them under hot state, easily soluble in dimethyl sulfoxide, insoluble in hexane, benzene, ether. Color reaction: positive by periodic acid- benzidine reagent, etc. And/or crematosine II. Appearance: colorless fine needlelike crystal. Melting point: 232W236°C. Value of elemental analysis: C 46.15%, H 4.54%, N 22.44%. Solubility: soluble in water under cold state, easily soluble in them under hot state, slightly soluble in methanol under cold state, soluble under hot state, easily soluble in dimethyl sulfoxide, and insoluble in hexane, benzene, ether. Color reaction: positive by periodic acid-benzidine reagent, etc.
USE: Having hypotensive actions, useful as an antihypertensive.
PROCESS: Cremastra appendiculata is extracted with an organic polar solvent, or a mixed solvent with water, to give an extracted solution, from which a cremastosine is isolated.
COPYRIGHT: (C)1982,JPO&Japio
JP11073080A 1980-08-12 1980-08-12 Cremastosine 1 and/or cremastosine 2 Pending JPS5735518A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP11073080A JPS5735518A (en) 1980-08-12 1980-08-12 Cremastosine 1 and/or cremastosine 2

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP11073080A JPS5735518A (en) 1980-08-12 1980-08-12 Cremastosine 1 and/or cremastosine 2

Publications (1)

Publication Number Publication Date
JPS5735518A true JPS5735518A (en) 1982-02-26

Family

ID=14543045

Family Applications (1)

Application Number Title Priority Date Filing Date
JP11073080A Pending JPS5735518A (en) 1980-08-12 1980-08-12 Cremastosine 1 and/or cremastosine 2

Country Status (1)

Country Link
JP (1) JPS5735518A (en)

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