JPS57212169A - Guanidine derivative and its preparation - Google Patents

Guanidine derivative and its preparation

Info

Publication number
JPS57212169A
JPS57212169A JP56098940A JP9894081A JPS57212169A JP S57212169 A JPS57212169 A JP S57212169A JP 56098940 A JP56098940 A JP 56098940A JP 9894081 A JP9894081 A JP 9894081A JP S57212169 A JPS57212169 A JP S57212169A
Authority
JP
Japan
Prior art keywords
methyl
guanidine
preparation
formula
guanidine derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP56098940A
Other languages
Japanese (ja)
Inventor
Dotaro Fujimoto
Giichi Funatsukuri
Ryuichi Fukui
Shuhei Takamatsu
Takeshi Sakai
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fujimoto Pharmaceutical Corp
Original Assignee
Fujimoto Pharmaceutical Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujimoto Pharmaceutical Corp filed Critical Fujimoto Pharmaceutical Corp
Priority to JP56098940A priority Critical patent/JPS57212169A/en
Publication of JPS57212169A publication Critical patent/JPS57212169A/en
Pending legal-status Critical Current

Links

Abstract

NEW MATERIAL:A guanidine derivative of formulaI(Bz is formula II, connecting to 1- or 3-position).
EXAMPLE: N-methyl-N'-cyano-N"-2-{[({[1-benzyl-4-methyl-5-imidazoyl)methylthio] ethyl]guanidine.
USE: It has a pharmacological activity such as inhibition of stomach acid secretion.
PREPARATION: The reaction of N-methyl-N'-cyano-N"-{2[4-methyl-5-imidazoyl) methylthio]ethyl}guanidine of formula III or its salt with benzyl chloride of formula IV is carried out in a solvent, preferably in the presence of a base, at room temperature to 150°C for 5W12hr to give the compound of formulaI.
COPYRIGHT: (C)1982,JPO&Japio
JP56098940A 1981-06-25 1981-06-25 Guanidine derivative and its preparation Pending JPS57212169A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP56098940A JPS57212169A (en) 1981-06-25 1981-06-25 Guanidine derivative and its preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP56098940A JPS57212169A (en) 1981-06-25 1981-06-25 Guanidine derivative and its preparation

Publications (1)

Publication Number Publication Date
JPS57212169A true JPS57212169A (en) 1982-12-27

Family

ID=14233109

Family Applications (1)

Application Number Title Priority Date Filing Date
JP56098940A Pending JPS57212169A (en) 1981-06-25 1981-06-25 Guanidine derivative and its preparation

Country Status (1)

Country Link
JP (1) JPS57212169A (en)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5698938A (en) * 1980-01-09 1981-08-08 Rohm Co Ltd Signal switching circuit

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5698938A (en) * 1980-01-09 1981-08-08 Rohm Co Ltd Signal switching circuit

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