JPS57197252A - Preparation of 2-azido substituted unsaturated carboxylic acid derivative - Google Patents

Preparation of 2-azido substituted unsaturated carboxylic acid derivative

Info

Publication number
JPS57197252A
JPS57197252A JP8113081A JP8113081A JPS57197252A JP S57197252 A JPS57197252 A JP S57197252A JP 8113081 A JP8113081 A JP 8113081A JP 8113081 A JP8113081 A JP 8113081A JP S57197252 A JPS57197252 A JP S57197252A
Authority
JP
Japan
Prior art keywords
compound
formulai
alkyl
sodium azide
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP8113081A
Other languages
Japanese (ja)
Inventor
Masaaki Kakimoto
Mariko Kai
Sei Kondo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sagami Chemical Research Institute
Original Assignee
Sagami Chemical Research Institute
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sagami Chemical Research Institute filed Critical Sagami Chemical Research Institute
Priority to JP8113081A priority Critical patent/JPS57197252A/en
Publication of JPS57197252A publication Critical patent/JPS57197252A/en
Pending legal-status Critical Current

Links

Landscapes

  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

PURPOSE: To obtain the titled compound convertible into a constituent amino acid of physiologically active peptides in high yield in short steps, by reacting an easily available 2,3-disubstituted carboxylic ester with sodium azide in an aprotic polar solvent.
CONSTITUTION: A compound of formulaI(R1 is H, alkyl or aryl, R2 is H or alkyl; X is halogen, alkyl or arylsulfonyloxy) is reacted with sodium azide in an aprotic polar solvent, e.g. DMF, DMSO or hexamethylphosphoric triamide, to give the aimed compound of formula II. 2,3-Dichloropropionic acid, 3-bromo-2- chloropropionic acid, etc. may be cited as the compound of formulaI. The amount of the sodium azide to be used is preferably 2W4 equivalents based on the compound of formulaI. The reaction temperature of 40W80°C provides a high yield of the aimed compound.
COPYRIGHT: (C)1982,JPO&Japio
JP8113081A 1981-05-29 1981-05-29 Preparation of 2-azido substituted unsaturated carboxylic acid derivative Pending JPS57197252A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP8113081A JPS57197252A (en) 1981-05-29 1981-05-29 Preparation of 2-azido substituted unsaturated carboxylic acid derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP8113081A JPS57197252A (en) 1981-05-29 1981-05-29 Preparation of 2-azido substituted unsaturated carboxylic acid derivative

Publications (1)

Publication Number Publication Date
JPS57197252A true JPS57197252A (en) 1982-12-03

Family

ID=13737808

Family Applications (1)

Application Number Title Priority Date Filing Date
JP8113081A Pending JPS57197252A (en) 1981-05-29 1981-05-29 Preparation of 2-azido substituted unsaturated carboxylic acid derivative

Country Status (1)

Country Link
JP (1) JPS57197252A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4572747A (en) * 1984-02-02 1986-02-25 Armco Inc. Method of producing boron alloy

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4572747A (en) * 1984-02-02 1986-02-25 Armco Inc. Method of producing boron alloy

Similar Documents

Publication Publication Date Title
NO160713C (en) PROCEDURE FOR THE PREPARATION OF BETA CARBOL INGREDIENTS.
ES8106482A1 (en) Phenyl-alkanoic acid derivatives, the preparation thereof and pharmaceutical compositions containing them.
JPS57197252A (en) Preparation of 2-azido substituted unsaturated carboxylic acid derivative
JPS557242A (en) Phenethylamine derivative
ES8307236A1 (en) Process for the preparation of a furan derivative.
JPS5632477A (en) Preparation of 1- 5-oxohexyl -3,7-dimethylxanthine
JPS57192340A (en) Isoprenylamine derivative
JPS5735556A (en) Preparation of guanidinomethylcyclohexanecarboxylic acid ester
JPS5256193A (en) Process for copolyesterpolyol
ES8506689A1 (en) Cumalincarboxylic-acid esters, process for their preparation and agricultural fungicides.
JPS57165357A (en) Novel optically active azidocarboxylic acid or ester thereof and its preparation
JPS54112848A (en) Preparation of 3beta-hydroxy-24-oxo-5alpha-cholestane-5-ene
SE7909816L (en) PROCEDURE FOR PREPARING A THERAPEUTIC ACTIVE AMINE
SU667130A3 (en) Method of producing salt of lysine and alpha-methyl-(2-isopropyl-5-indanyl) of acetic acid
GB1491606A (en) Process for the preparation of aliphatic beta-ketoesters
JPS5659732A (en) Preparation of phenoxycarboxylic acid derivative
JPS55108857A (en) Preparation of 5-fluorouracil derivative
JPS54106421A (en) Preparation of carboxylic acid derivative
JPS572268A (en) Preparation of 5- p-chlorobenzoyl -1,4-dimethylpyrrole- 2-acetic acid
JPS56123964A (en) 1- n-benzyl-o- 2,6-dichloroanilino phenyl -2-methylsulfinyl- 2-methylthioethylene
JPS57197253A (en) Preparation of 2-azido unsaturated carboxylic acid derivative
JPS57130977A (en) Preparation of 2-hydroxyquinoxaline
EP0081320A3 (en) Preparation of acetic acid derivatives
JPS57156447A (en) Ether compound and its synthesis
JPS5759869A (en) Preparation of 4-benzoyl-5-hydroxypyrazole compound