SE7909816L - PROCEDURE FOR PREPARING A THERAPEUTIC ACTIVE AMINE - Google Patents
PROCEDURE FOR PREPARING A THERAPEUTIC ACTIVE AMINEInfo
- Publication number
- SE7909816L SE7909816L SE7909816A SE7909816A SE7909816L SE 7909816 L SE7909816 L SE 7909816L SE 7909816 A SE7909816 A SE 7909816A SE 7909816 A SE7909816 A SE 7909816A SE 7909816 L SE7909816 L SE 7909816L
- Authority
- SE
- Sweden
- Prior art keywords
- compound
- preparing
- procedure
- active amine
- therapeutic active
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
- C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
- C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
- C07D303/24—Ethers with hydroxy compounds containing no oxirane rings with polyhydroxy compounds
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
A process for preparing the therapeutically valuable compound 1-isopropylamino-3-(4-(2-methoxyethyl)phenoxy)-2- propanol consists in a compound of the formula <IMAGE> where X is a reactive ester radical, being reacted with an isopropylamine acid addition salt to give a compound of the formula <IMAGE> where X has the same meaning as above, after which this compound is reacted with an alkali metal methoxide or with methanol in the presence of an acid catalyst. The reactive ester radical X is stated, by way of example, to be tosyloxy or halogen, in which case the compounds IV and V, respectively, are previously unknown.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FI783646A FI58909C (en) | 1978-11-29 | 1978-11-29 | REFERENCE FOR THERAPEUTIC ACTIVATION OF THERAPEUTIC ACTIVATING OF 1-ISOPROPYLAMINO-3- (4- (2-METHOXYETHYL) -PHENOXY) -2-PROPANOL OCH DESS SYRAADDITIONSSALTER |
Publications (2)
Publication Number | Publication Date |
---|---|
SE7909816L true SE7909816L (en) | 1980-05-30 |
SE443779B SE443779B (en) | 1986-03-10 |
Family
ID=8512188
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE7909816A SE443779B (en) | 1978-11-29 | 1979-11-28 | PROCEDURE FOR PREPARING THE THERAPEUTICALLY ACTIVE COMPOUND 1-ISOPROPYLAMINO-3- / 4- (2-METOXYETHYL) PHENOXY / -2-PROPANOL AND ITS ACID ADDITION SALTS |
Country Status (5)
Country | Link |
---|---|
DK (1) | DK154072C (en) |
FI (1) | FI58909C (en) |
NL (1) | NL7908669A (en) |
NO (1) | NO793871L (en) |
SE (1) | SE443779B (en) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101665441B (en) * | 2009-09-18 | 2013-04-10 | 安徽省庆云医药化工有限公司 | Method for preparing l-betaxolol hydrochloride |
CN102381995B (en) * | 2010-08-31 | 2015-04-15 | 扬子江药业集团北京海燕药业有限公司 | Preparation method of metoprolol |
-
1978
- 1978-11-29 FI FI783646A patent/FI58909C/en not_active IP Right Cessation
-
1979
- 1979-11-28 NO NO793871A patent/NO793871L/en unknown
- 1979-11-28 DK DK504879A patent/DK154072C/en not_active IP Right Cessation
- 1979-11-28 SE SE7909816A patent/SE443779B/en not_active IP Right Cessation
- 1979-11-29 NL NL7908669A patent/NL7908669A/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
DK154072B (en) | 1988-10-10 |
FI783646A (en) | 1980-05-30 |
FI58909B (en) | 1981-01-30 |
NO793871L (en) | 1980-05-30 |
NL7908669A (en) | 1980-06-02 |
FI58909C (en) | 1981-05-11 |
SE443779B (en) | 1986-03-10 |
DK154072C (en) | 1989-03-06 |
DK504879A (en) | 1980-05-30 |
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Legal Events
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---|---|---|---|
NUG | Patent has lapsed |
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