SE7909816L - PROCEDURE FOR PREPARING A THERAPEUTIC ACTIVE AMINE - Google Patents

PROCEDURE FOR PREPARING A THERAPEUTIC ACTIVE AMINE

Info

Publication number
SE7909816L
SE7909816L SE7909816A SE7909816A SE7909816L SE 7909816 L SE7909816 L SE 7909816L SE 7909816 A SE7909816 A SE 7909816A SE 7909816 A SE7909816 A SE 7909816A SE 7909816 L SE7909816 L SE 7909816L
Authority
SE
Sweden
Prior art keywords
compound
preparing
procedure
active amine
therapeutic active
Prior art date
Application number
SE7909816A
Other languages
Swedish (sv)
Other versions
SE443779B (en
Inventor
S K Huhta
A J Karjalainen
Original Assignee
Farmos Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmos Oy filed Critical Farmos Oy
Publication of SE7909816L publication Critical patent/SE7909816L/en
Publication of SE443779B publication Critical patent/SE443779B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D303/00Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02Compounds containing oxirane rings
    • C07D303/12Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/20Ethers with hydroxy compounds containing no oxirane rings
    • C07D303/24Ethers with hydroxy compounds containing no oxirane rings with polyhydroxy compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

A process for preparing the therapeutically valuable compound 1-isopropylamino-3-(4-(2-methoxyethyl)phenoxy)-2- propanol consists in a compound of the formula <IMAGE> where X is a reactive ester radical, being reacted with an isopropylamine acid addition salt to give a compound of the formula <IMAGE> where X has the same meaning as above, after which this compound is reacted with an alkali metal methoxide or with methanol in the presence of an acid catalyst. The reactive ester radical X is stated, by way of example, to be tosyloxy or halogen, in which case the compounds IV and V, respectively, are previously unknown.
SE7909816A 1978-11-29 1979-11-28 PROCEDURE FOR PREPARING THE THERAPEUTICALLY ACTIVE COMPOUND 1-ISOPROPYLAMINO-3- / 4- (2-METOXYETHYL) PHENOXY / -2-PROPANOL AND ITS ACID ADDITION SALTS SE443779B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FI783646A FI58909C (en) 1978-11-29 1978-11-29 REFERENCE FOR THERAPEUTIC ACTIVATION OF THERAPEUTIC ACTIVATING OF 1-ISOPROPYLAMINO-3- (4- (2-METHOXYETHYL) -PHENOXY) -2-PROPANOL OCH DESS SYRAADDITIONSSALTER

Publications (2)

Publication Number Publication Date
SE7909816L true SE7909816L (en) 1980-05-30
SE443779B SE443779B (en) 1986-03-10

Family

ID=8512188

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7909816A SE443779B (en) 1978-11-29 1979-11-28 PROCEDURE FOR PREPARING THE THERAPEUTICALLY ACTIVE COMPOUND 1-ISOPROPYLAMINO-3- / 4- (2-METOXYETHYL) PHENOXY / -2-PROPANOL AND ITS ACID ADDITION SALTS

Country Status (5)

Country Link
DK (1) DK154072C (en)
FI (1) FI58909C (en)
NL (1) NL7908669A (en)
NO (1) NO793871L (en)
SE (1) SE443779B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101665441B (en) * 2009-09-18 2013-04-10 安徽省庆云医药化工有限公司 Method for preparing l-betaxolol hydrochloride
CN102381995B (en) * 2010-08-31 2015-04-15 扬子江药业集团北京海燕药业有限公司 Preparation method of metoprolol

Also Published As

Publication number Publication date
DK154072B (en) 1988-10-10
FI783646A (en) 1980-05-30
FI58909B (en) 1981-01-30
NO793871L (en) 1980-05-30
NL7908669A (en) 1980-06-02
FI58909C (en) 1981-05-11
SE443779B (en) 1986-03-10
DK154072C (en) 1989-03-06
DK504879A (en) 1980-05-30

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