JPS5718727A - Reactive polymer and its preparation - Google Patents
Reactive polymer and its preparationInfo
- Publication number
- JPS5718727A JPS5718727A JP9166180A JP9166180A JPS5718727A JP S5718727 A JPS5718727 A JP S5718727A JP 9166180 A JP9166180 A JP 9166180A JP 9166180 A JP9166180 A JP 9166180A JP S5718727 A JPS5718727 A JP S5718727A
- Authority
- JP
- Japan
- Prior art keywords
- group
- polymer
- active
- reactive polymer
- molecule
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229920013730 reactive polymer Polymers 0.000 title abstract 3
- 229920000642 polymer Polymers 0.000 abstract 5
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 abstract 2
- 230000000259 anti-tumor effect Effects 0.000 abstract 2
- 230000003327 cancerostatic effect Effects 0.000 abstract 2
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 2
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- 231100000433 cytotoxic Toxicity 0.000 abstract 2
- 230000001472 cytotoxic effect Effects 0.000 abstract 2
- 239000000126 substance Substances 0.000 abstract 2
- 239000004471 Glycine Substances 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 150000001370 alpha-amino acid derivatives Chemical group 0.000 abstract 1
- 235000008206 alpha-amino acids Nutrition 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- 150000001768 cations Chemical class 0.000 abstract 1
- 239000000470 constituent Substances 0.000 abstract 1
- 125000002228 disulfide group Chemical group 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 125000001841 imino group Chemical group [H]N=* 0.000 abstract 1
- 125000000962 organic group Chemical group 0.000 abstract 1
- 238000006116 polymerization reaction Methods 0.000 abstract 1
- 230000009257 reactivity Effects 0.000 abstract 1
- 210000004881 tumor cell Anatomy 0.000 abstract 1
Landscapes
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Polyamides (AREA)
Priority Applications (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP9166180A JPS5718727A (en) | 1980-07-07 | 1980-07-07 | Reactive polymer and its preparation |
| DE8181302118T DE3175151D1 (en) | 1980-05-21 | 1981-05-13 | Reactive polymer and process for the preparation thereof |
| EP81302118A EP0040506B1 (en) | 1980-05-21 | 1981-05-13 | Reactive polymer and process for the preparation thereof |
| US06/265,924 US4385169A (en) | 1980-05-21 | 1981-05-21 | Reactive alpha amino acid polymer |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP9166180A JPS5718727A (en) | 1980-07-07 | 1980-07-07 | Reactive polymer and its preparation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS5718727A true JPS5718727A (en) | 1982-01-30 |
| JPS6238368B2 JPS6238368B2 (enrdf_load_stackoverflow) | 1987-08-18 |
Family
ID=14032669
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP9166180A Granted JPS5718727A (en) | 1980-05-21 | 1980-07-07 | Reactive polymer and its preparation |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS5718727A (enrdf_load_stackoverflow) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS59116232A (ja) * | 1982-12-24 | 1984-07-05 | Teijin Ltd | 細胞毒性複合体及びその製造法 |
| JPS59159828A (ja) * | 1983-03-02 | 1984-09-10 | Teijin Ltd | 反応性重合体の製造法 |
| JPH03236331A (ja) * | 1981-10-19 | 1991-10-22 | Ortho Diagnostic Syst Inc | 組織に対して特異的な治療剤 |
| JPH03287545A (ja) * | 1990-03-31 | 1991-12-18 | Res Dev Corp Of Japan | 標的指向性高分子医薬化合物及びその中間体 |
| JPH0688913B2 (ja) * | 1988-08-19 | 1994-11-09 | タノックス・バイオシステムズ・インコーポレーテッド | 細胞膜ブレンディング剤を含む分子共役体 |
| WO1995009009A1 (fr) * | 1993-09-28 | 1995-04-06 | Hisamitsu Pharmaceutical Co., Inc. | Excipient constitue d'acides polyamines pour oligonucleotide |
-
1980
- 1980-07-07 JP JP9166180A patent/JPS5718727A/ja active Granted
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH03236331A (ja) * | 1981-10-19 | 1991-10-22 | Ortho Diagnostic Syst Inc | 組織に対して特異的な治療剤 |
| JPS59116232A (ja) * | 1982-12-24 | 1984-07-05 | Teijin Ltd | 細胞毒性複合体及びその製造法 |
| JPS59159828A (ja) * | 1983-03-02 | 1984-09-10 | Teijin Ltd | 反応性重合体の製造法 |
| JPH0688913B2 (ja) * | 1988-08-19 | 1994-11-09 | タノックス・バイオシステムズ・インコーポレーテッド | 細胞膜ブレンディング剤を含む分子共役体 |
| JPH03287545A (ja) * | 1990-03-31 | 1991-12-18 | Res Dev Corp Of Japan | 標的指向性高分子医薬化合物及びその中間体 |
| WO1995009009A1 (fr) * | 1993-09-28 | 1995-04-06 | Hisamitsu Pharmaceutical Co., Inc. | Excipient constitue d'acides polyamines pour oligonucleotide |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6238368B2 (enrdf_load_stackoverflow) | 1987-08-18 |
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