JPS57181018A - Polysaccharide ps-c from plant of genus epimedium, its preparation, and immune enhancer comprising polysaccharide ps-c as active ingredient - Google Patents

Polysaccharide ps-c from plant of genus epimedium, its preparation, and immune enhancer comprising polysaccharide ps-c as active ingredient

Info

Publication number
JPS57181018A
JPS57181018A JP56065893A JP6589381A JPS57181018A JP S57181018 A JPS57181018 A JP S57181018A JP 56065893 A JP56065893 A JP 56065893A JP 6589381 A JP6589381 A JP 6589381A JP S57181018 A JPS57181018 A JP S57181018A
Authority
JP
Japan
Prior art keywords
polysaccharide
water
solution
plant
give
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP56065893A
Other languages
Japanese (ja)
Inventor
Susumu Mihashi
Muneaki Takase
Sousuke Yasui
Tomoo Washisawa
Kimitomo Yoshioka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zenyaku Kogyo KK
Original Assignee
Zenyaku Kogyo KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zenyaku Kogyo KK filed Critical Zenyaku Kogyo KK
Priority to JP56065893A priority Critical patent/JPS57181018A/en
Priority to EP82901157A priority patent/EP0086233A1/en
Priority to PCT/JP1982/000132 priority patent/WO1982003771A1/en
Priority to DE19823242672 priority patent/DE3242672T1/en
Priority to GB838314489A priority patent/GB8314489D0/en
Priority to US06/456,027 priority patent/US4528188A/en
Priority to AU83346/82A priority patent/AU8334682A/en
Priority to CA000401970A priority patent/CA1188687A/en
Publication of JPS57181018A publication Critical patent/JPS57181018A/en
Pending legal-status Critical Current

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  • Medicines Containing Plant Substances (AREA)

Abstract

PURPOSE: To obtain the titled drug capable of promoting the function of a chemotherapeutical drug by medicating the titled drug and the chemotherapeutical drug, etc. to a patient with reduced immune function, by comprising a polysaccharide PS-C which is extracted from a plant of the genus epimedium, isolated and purified, as an active ingredient.
CONSTITUTION: A mixed solvent of water and an organic solvent (e.g., lower alcohol, etc.) compatible with water is added to a plant of the genus epimedium to give an aqueous extracted solution. An organic solvent compatible with water in any ratio is added to the solution to give a precipitate, which is dissolved in water. A long-chain quaternary ammonium salt is added to the solution, formed compounded substances are removed, the solution is purified by chromatography, etc., to give the desired fraction. Elemental analysis: C 40.75, H 6.28, ash trace amount. Molecular weight: 25,000±15,000. Properties of substance: white slightly brown amorphous powder. Decomposition point: 175°C pH: 7.0. Constitutional saccharide: found to have physical and chemical properties of arabinose, galactose, etc., and immnue enhancing action.
COPYRIGHT: (C)1982,JPO&Japio
JP56065893A 1981-04-30 1981-04-30 Polysaccharide ps-c from plant of genus epimedium, its preparation, and immune enhancer comprising polysaccharide ps-c as active ingredient Pending JPS57181018A (en)

Priority Applications (8)

Application Number Priority Date Filing Date Title
JP56065893A JPS57181018A (en) 1981-04-30 1981-04-30 Polysaccharide ps-c from plant of genus epimedium, its preparation, and immune enhancer comprising polysaccharide ps-c as active ingredient
EP82901157A EP0086233A1 (en) 1981-04-30 1982-04-20 Polysaccharide ps-a isolated from the plant of genus epimedium violaceum morr. et decne., process for its preparation, and infection-preventing agent and immunostimulating agent containing the polysaccharide as effective ingredient
PCT/JP1982/000132 WO1982003771A1 (en) 1981-04-30 1982-04-20 Polysaccharide ps-a isolated from the plant of genus epimedium violaceum morr,et decne.,process for its preparation,and infection-preventing agent and immunostimulating agent containing the polysaccharide as effective ingredient
DE19823242672 DE3242672T1 (en) 1981-04-30 1982-04-20 POLYSACCHARID PS-A RECEIVE PLANTS OF THE GENERATION EPIMEDIUM, METHOD FOR THE PRODUCTION THEREOF AND PHYLACTIC AND IMMUNOSTIMULATING AGENTS WHICH CONTAIN THIS POLYSACCHARIDE PS-A AS AN ACTIVE COMPONENT
GB838314489A GB8314489D0 (en) 1981-04-30 1982-04-20 Polysaccharide ps-a
US06/456,027 US4528188A (en) 1981-04-30 1982-04-20 Polysaccharide PS-A obtained from barrenwort deriving from plants belonging to the genus Epimedium, process for preparation thereof and phylactic and immunostimulating agents comprising said polysaccharide PS-A effective component
AU83346/82A AU8334682A (en) 1981-04-30 1982-04-20 Polysaccharide ps=a isolated from the plant of genus epimedium violaceium morr. et decne., process for its preparation, and infection-preventing agent and immunostimulating agent containing the ploysaccharide as effective ingredient
CA000401970A CA1188687A (en) 1981-04-30 1982-04-29 Polysaccharide ps-a obtained from plants of genus epimedium sp., process for preparation thereof and phylactic and immunostimulating agents comprising said polysaccharide ps-a as effective component

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP56065893A JPS57181018A (en) 1981-04-30 1981-04-30 Polysaccharide ps-c from plant of genus epimedium, its preparation, and immune enhancer comprising polysaccharide ps-c as active ingredient

Publications (1)

Publication Number Publication Date
JPS57181018A true JPS57181018A (en) 1982-11-08

Family

ID=13300092

Family Applications (1)

Application Number Title Priority Date Filing Date
JP56065893A Pending JPS57181018A (en) 1981-04-30 1981-04-30 Polysaccharide ps-c from plant of genus epimedium, its preparation, and immune enhancer comprising polysaccharide ps-c as active ingredient

Country Status (1)

Country Link
JP (1) JPS57181018A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013541625A (en) * 2010-11-05 2013-11-14 インスティテュート オブ ファーマコロジー アンド トキシコロジー アカデミー オブ ミリタリー メディカル サイエンシズ ピー．エル．エー．チャイナ Epimedium polysaccharide, its fractions, and its use as a vaccine adjuvant

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013541625A (en) * 2010-11-05 2013-11-14 インスティテュート オブ ファーマコロジー アンド トキシコロジー アカデミー オブ ミリタリー メディカル サイエンシズ ピー．エル．エー．チャイナ Epimedium polysaccharide, its fractions, and its use as a vaccine adjuvant

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