JPS5716885A - 3,4-benzo-7-thia-2-azabicyclo 3,3,1 nonane derivative - Google Patents

3,4-benzo-7-thia-2-azabicyclo 3,3,1 nonane derivative

Info

Publication number
JPS5716885A
JPS5716885A JP9209780A JP9209780A JPS5716885A JP S5716885 A JPS5716885 A JP S5716885A JP 9209780 A JP9209780 A JP 9209780A JP 9209780 A JP9209780 A JP 9209780A JP S5716885 A JPS5716885 A JP S5716885A
Authority
JP
Japan
Prior art keywords
lower alkyl
alkoxy
thia
azabicyclo
benzo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP9209780A
Other languages
Japanese (ja)
Other versions
JPH0161109B2 (en
Inventor
Yoshiki Hamada
Retsu Takeuchi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Otsuka Pharmaceutical Co Ltd
Original Assignee
Otsuka Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharmaceutical Co Ltd filed Critical Otsuka Pharmaceutical Co Ltd
Priority to JP9209780A priority Critical patent/JPS5716885A/en
Publication of JPS5716885A publication Critical patent/JPS5716885A/en
Publication of JPH0161109B2 publication Critical patent/JPH0161109B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:The titled nonane derivatives of formula I [R1 is H, lower alkyl; R2 is lower alkyl; R3 is H, lower alkyl, lower alkoxy, phenyl-lower-alkoxy, hydroxyl; wherein R3 is not H, when R1 is H and R2 is methyl] or their salts.
EXAMPLE: 1-Ethyl-3,4-benzo-7-thia-2-azabicyclo[3,3,1]nonane-7-oxide.
USE: Anticonvulsive, muscle relaxant, analgesic.
PREPARATION: For example, a basic compound such as sodium hydroxide and dimethyl sulfoxide are previously heated in the reaction system, preferably to about 70°C. Then, a quinoline derivative of formula II (R4 is H, lower alkyl, lower alkoxy, phenyl-lower-alkoxy) such as 2-ethylquinoline is added to the reaction system. They are heated at about 70°C for 0.5W5hrs to produce the compound of formula I where R1 is H and R3 is H or lower alkyl.
COPYRIGHT: (C)1982,JPO&Japio
JP9209780A 1980-07-04 1980-07-04 3,4-benzo-7-thia-2-azabicyclo 3,3,1 nonane derivative Granted JPS5716885A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP9209780A JPS5716885A (en) 1980-07-04 1980-07-04 3,4-benzo-7-thia-2-azabicyclo 3,3,1 nonane derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP9209780A JPS5716885A (en) 1980-07-04 1980-07-04 3,4-benzo-7-thia-2-azabicyclo 3,3,1 nonane derivative

Publications (2)

Publication Number Publication Date
JPS5716885A true JPS5716885A (en) 1982-01-28
JPH0161109B2 JPH0161109B2 (en) 1989-12-27

Family

ID=14044936

Family Applications (1)

Application Number Title Priority Date Filing Date
JP9209780A Granted JPS5716885A (en) 1980-07-04 1980-07-04 3,4-benzo-7-thia-2-azabicyclo 3,3,1 nonane derivative

Country Status (1)

Country Link
JP (1) JPS5716885A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07137023A (en) * 1993-11-18 1995-05-30 Asahi Concrete Works Co Ltd Manufacture of tubular concrete product

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07137023A (en) * 1993-11-18 1995-05-30 Asahi Concrete Works Co Ltd Manufacture of tubular concrete product

Also Published As

Publication number Publication date
JPH0161109B2 (en) 1989-12-27

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