JPS57162701A - Production of anticoagulant regenerated cellulose - Google Patents

Production of anticoagulant regenerated cellulose

Info

Publication number
JPS57162701A
JPS57162701A JP56046286A JP4628681A JPS57162701A JP S57162701 A JPS57162701 A JP S57162701A JP 56046286 A JP56046286 A JP 56046286A JP 4628681 A JP4628681 A JP 4628681A JP S57162701 A JPS57162701 A JP S57162701A
Authority
JP
Japan
Prior art keywords
regenerated cellulose
cellulose
pts
methacrylate
heparin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP56046286A
Other languages
Japanese (ja)
Other versions
JPS5941647B2 (en
Inventor
Noriyuki Sugi
Yoshiaki Nitori
Yoshio Enomoto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
National Institute of Advanced Industrial Science and Technology AIST
Original Assignee
Agency of Industrial Science and Technology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Agency of Industrial Science and Technology filed Critical Agency of Industrial Science and Technology
Priority to JP56046286A priority Critical patent/JPS5941647B2/en
Publication of JPS57162701A publication Critical patent/JPS57162701A/en
Publication of JPS5941647B2 publication Critical patent/JPS5941647B2/en
Expired legal-status Critical Current

Links

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  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Materials For Medical Uses (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)

Abstract

PURPOSE: Heparin is made to act on a reaction product between regenerated cellulose, glycidyl acrylate or methacrylate and other vinyl monomers to produce the titled cellulose of high anticogulant property, used for hemodialysis, because it can reacts under mild conditions.
CONSTITUTION: The reaction between (A) formed regenerated cellulose or its derivative such as cuprammonium rayon, (B) 1×10-6W1.2×10-2pts.wt. per 1pt of water, of glycidyl acrylate or methacrylate and (C) 0.5×10-6pts. of vinyl monomers other than component a such as N-vinylpyrrolidone is conducted in the presence of a polymerization initiator such as ceric ammonium nitrate in an aqueous solvent at the freezing point to 60°C. After washed with water, the product is dipped in a heparin aqueous solution and stood at room temperature to 80°C in a closed system to give the objective cellulose.
COPYRIGHT: (C)1982,JPO&Japio
JP56046286A 1981-03-31 1981-03-31 Method for producing anticoagulant regenerated cellulose Expired JPS5941647B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP56046286A JPS5941647B2 (en) 1981-03-31 1981-03-31 Method for producing anticoagulant regenerated cellulose

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP56046286A JPS5941647B2 (en) 1981-03-31 1981-03-31 Method for producing anticoagulant regenerated cellulose

Publications (2)

Publication Number Publication Date
JPS57162701A true JPS57162701A (en) 1982-10-06
JPS5941647B2 JPS5941647B2 (en) 1984-10-08

Family

ID=12742968

Family Applications (1)

Application Number Title Priority Date Filing Date
JP56046286A Expired JPS5941647B2 (en) 1981-03-31 1981-03-31 Method for producing anticoagulant regenerated cellulose

Country Status (1)

Country Link
JP (1) JPS5941647B2 (en)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3341113A1 (en) * 1983-11-12 1985-05-23 Akzo Gmbh, 5600 Wuppertal DIALYSIS MEMBRANE WITH IMPROVED TOLERABILITY
DE3410133A1 (en) * 1984-03-20 1985-10-03 Akzo Gmbh, 5600 Wuppertal Dialysis membrane made of cellulose with improved biocompatibility
US4741927A (en) * 1984-03-20 1988-05-03 Akzo Nv Production of cellulose dialysis membrane with improved biocompatibility
JPS63102752A (en) * 1986-09-29 1988-05-07 ジヨンソン・アンド・ジヨンソン・プロダクツ・インコーポレイテツド Fusion preventing barrier containing heparin and method
US4962140A (en) * 1988-04-28 1990-10-09 Akzo N.V. Process for producing cellulosic dialysis membranes having improved biocompatibility and device for carrying out the process
US5055570A (en) * 1988-08-04 1991-10-08 Akzo N.V. Cuprammonium-stable cellulose esters and carbamates for dialysis membranes

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3341113A1 (en) * 1983-11-12 1985-05-23 Akzo Gmbh, 5600 Wuppertal DIALYSIS MEMBRANE WITH IMPROVED TOLERABILITY
DE3341113C2 (en) * 1983-11-12 1989-05-24 Akzo Patente Gmbh, 5600 Wuppertal, De
US4882060A (en) * 1983-11-12 1989-11-21 Akzo Nv Dialysis membranes with improved compatibility
US5035801A (en) * 1983-11-12 1991-07-30 Akzo Nv Analysis membranes with improved compatibility
DE3410133A1 (en) * 1984-03-20 1985-10-03 Akzo Gmbh, 5600 Wuppertal Dialysis membrane made of cellulose with improved biocompatibility
US4741927A (en) * 1984-03-20 1988-05-03 Akzo Nv Production of cellulose dialysis membrane with improved biocompatibility
US4772393A (en) * 1984-03-20 1988-09-20 Akzo Nv Cellulose dialysis membrane with improved biocompatibility
JPS63102752A (en) * 1986-09-29 1988-05-07 ジヨンソン・アンド・ジヨンソン・プロダクツ・インコーポレイテツド Fusion preventing barrier containing heparin and method
US4962140A (en) * 1988-04-28 1990-10-09 Akzo N.V. Process for producing cellulosic dialysis membranes having improved biocompatibility and device for carrying out the process
US5055570A (en) * 1988-08-04 1991-10-08 Akzo N.V. Cuprammonium-stable cellulose esters and carbamates for dialysis membranes

Also Published As

Publication number Publication date
JPS5941647B2 (en) 1984-10-08

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