JPS57162701A - Production of anticoagulant regenerated cellulose - Google Patents
Production of anticoagulant regenerated celluloseInfo
- Publication number
- JPS57162701A JPS57162701A JP56046286A JP4628681A JPS57162701A JP S57162701 A JPS57162701 A JP S57162701A JP 56046286 A JP56046286 A JP 56046286A JP 4628681 A JP4628681 A JP 4628681A JP S57162701 A JPS57162701 A JP S57162701A
- Authority
- JP
- Japan
- Prior art keywords
- regenerated cellulose
- cellulose
- pts
- methacrylate
- heparin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Materials For Medical Uses (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Abstract
PURPOSE: Heparin is made to act on a reaction product between regenerated cellulose, glycidyl acrylate or methacrylate and other vinyl monomers to produce the titled cellulose of high anticogulant property, used for hemodialysis, because it can reacts under mild conditions.
CONSTITUTION: The reaction between (A) formed regenerated cellulose or its derivative such as cuprammonium rayon, (B) 1×10-6W1.2×10-2pts.wt. per 1pt of water, of glycidyl acrylate or methacrylate and (C) 0.5×10-6pts. of vinyl monomers other than component a such as N-vinylpyrrolidone is conducted in the presence of a polymerization initiator such as ceric ammonium nitrate in an aqueous solvent at the freezing point to 60°C. After washed with water, the product is dipped in a heparin aqueous solution and stood at room temperature to 80°C in a closed system to give the objective cellulose.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP56046286A JPS5941647B2 (en) | 1981-03-31 | 1981-03-31 | Method for producing anticoagulant regenerated cellulose |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP56046286A JPS5941647B2 (en) | 1981-03-31 | 1981-03-31 | Method for producing anticoagulant regenerated cellulose |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS57162701A true JPS57162701A (en) | 1982-10-06 |
JPS5941647B2 JPS5941647B2 (en) | 1984-10-08 |
Family
ID=12742968
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP56046286A Expired JPS5941647B2 (en) | 1981-03-31 | 1981-03-31 | Method for producing anticoagulant regenerated cellulose |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5941647B2 (en) |
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3341113A1 (en) * | 1983-11-12 | 1985-05-23 | Akzo Gmbh, 5600 Wuppertal | DIALYSIS MEMBRANE WITH IMPROVED TOLERABILITY |
DE3410133A1 (en) * | 1984-03-20 | 1985-10-03 | Akzo Gmbh, 5600 Wuppertal | Dialysis membrane made of cellulose with improved biocompatibility |
US4741927A (en) * | 1984-03-20 | 1988-05-03 | Akzo Nv | Production of cellulose dialysis membrane with improved biocompatibility |
JPS63102752A (en) * | 1986-09-29 | 1988-05-07 | ジヨンソン・アンド・ジヨンソン・プロダクツ・インコーポレイテツド | Fusion preventing barrier containing heparin and method |
US4962140A (en) * | 1988-04-28 | 1990-10-09 | Akzo N.V. | Process for producing cellulosic dialysis membranes having improved biocompatibility and device for carrying out the process |
US5055570A (en) * | 1988-08-04 | 1991-10-08 | Akzo N.V. | Cuprammonium-stable cellulose esters and carbamates for dialysis membranes |
-
1981
- 1981-03-31 JP JP56046286A patent/JPS5941647B2/en not_active Expired
Cited By (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3341113A1 (en) * | 1983-11-12 | 1985-05-23 | Akzo Gmbh, 5600 Wuppertal | DIALYSIS MEMBRANE WITH IMPROVED TOLERABILITY |
DE3341113C2 (en) * | 1983-11-12 | 1989-05-24 | Akzo Patente Gmbh, 5600 Wuppertal, De | |
US4882060A (en) * | 1983-11-12 | 1989-11-21 | Akzo Nv | Dialysis membranes with improved compatibility |
US5035801A (en) * | 1983-11-12 | 1991-07-30 | Akzo Nv | Analysis membranes with improved compatibility |
DE3410133A1 (en) * | 1984-03-20 | 1985-10-03 | Akzo Gmbh, 5600 Wuppertal | Dialysis membrane made of cellulose with improved biocompatibility |
US4741927A (en) * | 1984-03-20 | 1988-05-03 | Akzo Nv | Production of cellulose dialysis membrane with improved biocompatibility |
US4772393A (en) * | 1984-03-20 | 1988-09-20 | Akzo Nv | Cellulose dialysis membrane with improved biocompatibility |
JPS63102752A (en) * | 1986-09-29 | 1988-05-07 | ジヨンソン・アンド・ジヨンソン・プロダクツ・インコーポレイテツド | Fusion preventing barrier containing heparin and method |
US4962140A (en) * | 1988-04-28 | 1990-10-09 | Akzo N.V. | Process for producing cellulosic dialysis membranes having improved biocompatibility and device for carrying out the process |
US5055570A (en) * | 1988-08-04 | 1991-10-08 | Akzo N.V. | Cuprammonium-stable cellulose esters and carbamates for dialysis membranes |
Also Published As
Publication number | Publication date |
---|---|
JPS5941647B2 (en) | 1984-10-08 |
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