JPS57159796A - Novel macrolide antibiotic substance and its preparation - Google Patents

Novel macrolide antibiotic substance and its preparation

Info

Publication number
JPS57159796A
JPS57159796A JP4412781A JP4412781A JPS57159796A JP S57159796 A JPS57159796 A JP S57159796A JP 4412781 A JP4412781 A JP 4412781A JP 4412781 A JP4412781 A JP 4412781A JP S57159796 A JPS57159796 A JP S57159796A
Authority
JP
Japan
Prior art keywords
macrolide antibiotic
antibiotic substance
atcc
gram
methanol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP4412781A
Other languages
Japanese (ja)
Inventor
Rokuro Okamoto
Masao Yamamoto
Kazuaki Takada
Kouki Kiyoshima
Tomoyuki Ishikura
Hamao Umezawa
Tomio Takeuchi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SANRAKU OCEAN KK
Sanraku Inc
Sanraku Ocean Co Ltd
Original Assignee
SANRAKU OCEAN KK
Sanraku Inc
Sanraku Ocean Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SANRAKU OCEAN KK, Sanraku Inc, Sanraku Ocean Co Ltd filed Critical SANRAKU OCEAN KK
Priority to JP4412781A priority Critical patent/JPS57159796A/en
Publication of JPS57159796A publication Critical patent/JPS57159796A/en
Pending legal-status Critical Current

Links

Landscapes

  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:The 16-membered macrolide antibiotic substance YO-9010 (R is H) and YO-7625 (Y is group of formula II) of formulaI, having the following physical and chemical properties. White crystal; melting point, 138W142°C for 9010 and 133W137°C for 7625; specific rotation,[α]D22=-47.4° (C=0.95, methanol) for 9010 and [α]D12=-37.4° (C=1.5, methanol) for 7625; elemental analsis (%), C 61.36, H 8.72, N 1.76 (C38H62NO13)for 9010, and C 59.95, H 8.20, N 1.51 (C44H72NO17) for 7625; molecular weight, 741 for 9010 and 887 for 7625 (by mass espectrum), etc.
USE: Antibacterial agent for the prevention and remedy of infectious diseases caused by Gram-positive bacteria, Gram-negative bacteria, or mycoplasma, and intermediate for the synthesis of pharmaceuticals.
PROCESS: The compound can be prepared, e.g. by culturing Streptomyces fradiae YO-9010 strain (ATCC 31846) or YO-7625 strain (ATCC 31845) in a nutrient medium, and separating and recovering the produced compound.
COPYRIGHT: (C)1982,JPO&Japio
JP4412781A 1981-03-27 1981-03-27 Novel macrolide antibiotic substance and its preparation Pending JPS57159796A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP4412781A JPS57159796A (en) 1981-03-27 1981-03-27 Novel macrolide antibiotic substance and its preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP4412781A JPS57159796A (en) 1981-03-27 1981-03-27 Novel macrolide antibiotic substance and its preparation

Publications (1)

Publication Number Publication Date
JPS57159796A true JPS57159796A (en) 1982-10-01

Family

ID=12682939

Family Applications (1)

Application Number Title Priority Date Filing Date
JP4412781A Pending JPS57159796A (en) 1981-03-27 1981-03-27 Novel macrolide antibiotic substance and its preparation

Country Status (1)

Country Link
JP (1) JPS57159796A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59187793A (en) * 1983-03-30 1984-10-24 フア−ミタリア・カルロ・エルバ・ソシエタ・ペル・アツイオ−ニ Improvement in purification of tyrosin

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59187793A (en) * 1983-03-30 1984-10-24 フア−ミタリア・カルロ・エルバ・ソシエタ・ペル・アツイオ−ニ Improvement in purification of tyrosin
JPH031957B2 (en) * 1983-03-30 1991-01-11 Erba Farmitalia

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