Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Sogo Pharmaceutical Co Ltd
Original Assignee
Sogo Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sogo Pharmaceutical Co LtdfiledCriticalSogo Pharmaceutical Co Ltd
Priority to JP3460081ApriorityCriticalpatent/JPS57149295A/en
Publication of JPS57149295ApublicationCriticalpatent/JPS57149295A/en
PURPOSE: A specific compound, which is prepared, e.g., by reaction of N,N- ethyleneurethane with phosphorous acid, is subjected to hydrolysis to produce the titled compound used as a chemical for medical and industrial purposes in high purity and yield.
CONSTITUTION: The hydrolysis of a compound of formulaI(R1 is alkyl, alkoxyalkyl, cycloalkyl, aryl, aralkyl; R2WR5 are H, alkyl; R6 is alkyl, alkylene) such as diethylethoxycarbonylaminoethyl phosphonate with hydrobromic acid is conducted by heating them under reflux to give the objective compound. The compound of formulaIis obtained by reaction between O-ethyl-N,N-ethyleneurethane of formula II and a phosphorous acid derivative such as diethyl phosphite.
COPYRIGHT: (C)1982,JPO&Japio
JP3460081A1981-03-121981-03-12Production of ciliatine and its derivative
PendingJPS57149295A
(en)