JPS57139086A - Ethylene glycol derivative - Google Patents

Ethylene glycol derivative

Info

Publication number
JPS57139086A
JPS57139086A JP2446081A JP2446081A JPS57139086A JP S57139086 A JPS57139086 A JP S57139086A JP 2446081 A JP2446081 A JP 2446081A JP 2446081 A JP2446081 A JP 2446081A JP S57139086 A JPS57139086 A JP S57139086A
Authority
JP
Japan
Prior art keywords
formula
compound expressed
compound
reacted
action
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2446081A
Other languages
Japanese (ja)
Other versions
JPS6411029B2 (en
Inventor
Motoo Hozumi
Masaaki Nomura
Yoshio Yoshioka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Priority to JP2446081A priority Critical patent/JPS57139086A/en
Priority to US06/257,771 priority patent/US4551532A/en
Priority to DE8181301984T priority patent/DE3165196D1/en
Priority to EP81301984A priority patent/EP0040039B1/en
Priority to CA000377015A priority patent/CA1152069A/en
Publication of JPS57139086A publication Critical patent/JPS57139086A/en
Publication of JPS6411029B2 publication Critical patent/JPS6411029B2/ja
Granted legal-status Critical Current

Links

Abstract

NEW MATERIAL:A compound expressed by formulaI(R1 is 8W26C aliphatic hydrocarbon residue; R2WR4 are H, lower alkyl, or cyclic ammonio group; n is an integer 1W15) and a salt thereof.
EXAMPLE: 3,6,9,12,15-Pentaoxaheptacosyl 2-bromoethyl phosphate.
USE: A medicine, having the growth inhibitory action on tumorous cells and differentiation inducing action (cancer removing) action, capable of exhibiting improved effects on leukemia, solid cancers, etc. as an antitumor agent, and useful as an antifungal agent.
PROCESS: A compound expressed by formula II is reacted with a compound expressed by formula III (X and Y are halogen) to give a compound expressed by formula IV, which is then reacted with water to afford a compound of formula V. The resultant compound of formula V is then reacted with a compound expressed by formula VI to afford the compound expressed by formulaI.
COPYRIGHT: (C)1982,JPO&Japio
JP2446081A 1980-05-08 1981-02-20 Ethylene glycol derivative Granted JPS57139086A (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
JP2446081A JPS57139086A (en) 1981-02-20 1981-02-20 Ethylene glycol derivative
US06/257,771 US4551532A (en) 1980-05-08 1981-04-27 Ethylene glycol derivatives having anti-protozoan, anti-fungal and anti-tumor activity
DE8181301984T DE3165196D1 (en) 1980-05-08 1981-05-06 Ethylene glycol derivatives of ammonioethyl phosphate, their production and use
EP81301984A EP0040039B1 (en) 1980-05-08 1981-05-06 Ethylene glycol derivatives of ammonioethyl phosphate, their production and use
CA000377015A CA1152069A (en) 1980-05-08 1981-05-07 Ethylene glycol derivatives, their production and use

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2446081A JPS57139086A (en) 1981-02-20 1981-02-20 Ethylene glycol derivative

Publications (2)

Publication Number Publication Date
JPS57139086A true JPS57139086A (en) 1982-08-27
JPS6411029B2 JPS6411029B2 (en) 1989-02-23

Family

ID=12138772

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2446081A Granted JPS57139086A (en) 1980-05-08 1981-02-20 Ethylene glycol derivative

Country Status (1)

Country Link
JP (1) JPS57139086A (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4907646A (en) * 1987-10-30 1990-03-13 Matsushita Electric Industrial Co., Ltd. Heat exchanger
JP2001354679A (en) * 2000-06-09 2001-12-25 Nof Corp Phosphorylcholine derivative, intermediate, method for producing the same and use
KR100398892B1 (en) * 2000-10-05 2003-09-19 전길자 Novel antifungal compound and antifungal composition comprising same

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4907646A (en) * 1987-10-30 1990-03-13 Matsushita Electric Industrial Co., Ltd. Heat exchanger
JP2001354679A (en) * 2000-06-09 2001-12-25 Nof Corp Phosphorylcholine derivative, intermediate, method for producing the same and use
KR100398892B1 (en) * 2000-10-05 2003-09-19 전길자 Novel antifungal compound and antifungal composition comprising same

Also Published As

Publication number Publication date
JPS6411029B2 (en) 1989-02-23

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