JPS57139086A - Ethylene glycol derivative - Google Patents
Ethylene glycol derivativeInfo
- Publication number
- JPS57139086A JPS57139086A JP2446081A JP2446081A JPS57139086A JP S57139086 A JPS57139086 A JP S57139086A JP 2446081 A JP2446081 A JP 2446081A JP 2446081 A JP2446081 A JP 2446081A JP S57139086 A JPS57139086 A JP S57139086A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- compound expressed
- compound
- reacted
- action
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Abstract
NEW MATERIAL:A compound expressed by formulaI(R1 is 8W26C aliphatic hydrocarbon residue; R2WR4 are H, lower alkyl, or cyclic ammonio group; n is an integer 1W15) and a salt thereof.
EXAMPLE: 3,6,9,12,15-Pentaoxaheptacosyl 2-bromoethyl phosphate.
USE: A medicine, having the growth inhibitory action on tumorous cells and differentiation inducing action (cancer removing) action, capable of exhibiting improved effects on leukemia, solid cancers, etc. as an antitumor agent, and useful as an antifungal agent.
PROCESS: A compound expressed by formula II is reacted with a compound expressed by formula III (X and Y are halogen) to give a compound expressed by formula IV, which is then reacted with water to afford a compound of formula V. The resultant compound of formula V is then reacted with a compound expressed by formula VI to afford the compound expressed by formulaI.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2446081A JPS57139086A (en) | 1981-02-20 | 1981-02-20 | Ethylene glycol derivative |
US06/257,771 US4551532A (en) | 1980-05-08 | 1981-04-27 | Ethylene glycol derivatives having anti-protozoan, anti-fungal and anti-tumor activity |
DE8181301984T DE3165196D1 (en) | 1980-05-08 | 1981-05-06 | Ethylene glycol derivatives of ammonioethyl phosphate, their production and use |
EP81301984A EP0040039B1 (en) | 1980-05-08 | 1981-05-06 | Ethylene glycol derivatives of ammonioethyl phosphate, their production and use |
CA000377015A CA1152069A (en) | 1980-05-08 | 1981-05-07 | Ethylene glycol derivatives, their production and use |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2446081A JPS57139086A (en) | 1981-02-20 | 1981-02-20 | Ethylene glycol derivative |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS57139086A true JPS57139086A (en) | 1982-08-27 |
JPS6411029B2 JPS6411029B2 (en) | 1989-02-23 |
Family
ID=12138772
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2446081A Granted JPS57139086A (en) | 1980-05-08 | 1981-02-20 | Ethylene glycol derivative |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS57139086A (en) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4907646A (en) * | 1987-10-30 | 1990-03-13 | Matsushita Electric Industrial Co., Ltd. | Heat exchanger |
JP2001354679A (en) * | 2000-06-09 | 2001-12-25 | Nof Corp | Phosphorylcholine derivative, intermediate, method for producing the same and use |
KR100398892B1 (en) * | 2000-10-05 | 2003-09-19 | 전길자 | Novel antifungal compound and antifungal composition comprising same |
-
1981
- 1981-02-20 JP JP2446081A patent/JPS57139086A/en active Granted
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4907646A (en) * | 1987-10-30 | 1990-03-13 | Matsushita Electric Industrial Co., Ltd. | Heat exchanger |
JP2001354679A (en) * | 2000-06-09 | 2001-12-25 | Nof Corp | Phosphorylcholine derivative, intermediate, method for producing the same and use |
KR100398892B1 (en) * | 2000-10-05 | 2003-09-19 | 전길자 | Novel antifungal compound and antifungal composition comprising same |
Also Published As
Publication number | Publication date |
---|---|
JPS6411029B2 (en) | 1989-02-23 |
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