RU92016313A - NEW ANALOGUES OF VITAMIN D, METHOD OF THEIR PRODUCTION, INTERMEDIATE CONNECTION, FORMCOMPOSITION AND METHOD OF TREATMENT - Google Patents

NEW ANALOGUES OF VITAMIN D, METHOD OF THEIR PRODUCTION, INTERMEDIATE CONNECTION, FORMCOMPOSITION AND METHOD OF TREATMENT

Info

Publication number
RU92016313A
RU92016313A RU92016313/04A RU92016313A RU92016313A RU 92016313 A RU92016313 A RU 92016313A RU 92016313/04 A RU92016313/04 A RU 92016313/04A RU 92016313 A RU92016313 A RU 92016313A RU 92016313 A RU92016313 A RU 92016313A
Authority
RU
Russia
Prior art keywords
formcomposition
vitamin
treatment
production
intermediate connection
Prior art date
Application number
RU92016313/04A
Other languages
Russian (ru)
Other versions
RU2126384C1 (en
Inventor
Оге Свенсгорд Бреттинг Клаус
Original Assignee
Лео Фармасьютикал Продакт Лтд.
А/с (Левенс Кемиске Фабрик Продукционсактиесельскаб)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB909017890A external-priority patent/GB9017890D0/en
Application filed by Лео Фармасьютикал Продакт Лтд., А/с (Левенс Кемиске Фабрик Продукционсактиесельскаб) filed Critical Лео Фармасьютикал Продакт Лтд.
Publication of RU92016313A publication Critical patent/RU92016313A/en
Application granted granted Critical
Publication of RU2126384C1 publication Critical patent/RU2126384C1/en

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Claims (1)

Изобретение относится к соединениям формулы (1), в которых X является водородом или гидроксилом, R1 и R2 обозначают водород или С1 - С6-углеводород, или взытые вместе с атомом углерода, содержащим группу X, образуют С3 - С8-карбоциклическое кольцо; Q является простой связью или С1 - С8-углеводородным ненасышенным бирадикалом; m = 0,1 или 2; R1, R2 и/или Q могут быть необязательно замещены, и их производным. Соединения обладают противовоспалительной и иммуномодуляторной активностью, а также высокой способностью вызывать дифференциацию и ингибирование нежелательной пролиферации некоторых клеток.The invention relates to compounds of formula (1) in which X is hydrogen or hydroxyl, R 1 and R 2 denote hydrogen or C 1 - C 6 -hydrocarbon, or taken together with the carbon atom containing the group X, form C 3 - C 8 - carbocyclic ring; Q is a simple bond or C 1 - C 8 hydrocarbon unsaturated biradical; m = 0.1 or 2; R 1 , R 2 and / or Q can be optionally substituted, and their derivative. The compounds have anti-inflammatory and immunomodulatory activity, as well as a high ability to cause differentiation and inhibition of unwanted proliferation of certain cells.
RU92016313A 1990-08-15 1991-07-11 Vitamin d analogs, process for preparation thereof, intermediate composition, and method for suppressing morbid states RU2126384C1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB9017890/6 1990-08-15
GB909017890A GB9017890D0 (en) 1990-08-15 1990-08-15 Chemical compounds i
GB9017890.6 1990-08-15
PCT/DK1991/000200 WO1992003414A1 (en) 1990-08-15 1991-07-11 Novel vitamin d analogues

Publications (2)

Publication Number Publication Date
RU92016313A true RU92016313A (en) 1996-01-10
RU2126384C1 RU2126384C1 (en) 1999-02-20

Family

ID=10680686

Family Applications (1)

Application Number Title Priority Date Filing Date
RU92016313A RU2126384C1 (en) 1990-08-15 1991-07-11 Vitamin d analogs, process for preparation thereof, intermediate composition, and method for suppressing morbid states

Country Status (20)

Country Link
US (1) US5447924A (en)
EP (1) EP0543864B1 (en)
JP (1) JP3246914B2 (en)
KR (1) KR100203227B1 (en)
AT (1) ATE115562T1 (en)
AU (1) AU636510B2 (en)
CA (1) CA2078555C (en)
CZ (1) CZ286485B6 (en)
DE (1) DE69105981T2 (en)
DK (1) DK0543864T3 (en)
ES (1) ES2068601T3 (en)
FI (1) FI103791B (en)
GB (1) GB9017890D0 (en)
GR (1) GR3014922T3 (en)
IE (1) IE66241B1 (en)
LT (1) LT3666B (en)
LV (1) LV10089B (en)
RU (1) RU2126384C1 (en)
SK (1) SK281443B6 (en)
WO (1) WO1992003414A1 (en)

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BRPI0609630A2 (en) * 2005-05-10 2010-04-20 Dermipsor Ltd compositions and methods for treating hyperproliferative epidermal diseases
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