JPS57145893A - Antibiotic and its preparation - Google Patents

Antibiotic and its preparation

Info

Publication number
JPS57145893A
JPS57145893A JP56031983A JP3198381A JPS57145893A JP S57145893 A JPS57145893 A JP S57145893A JP 56031983 A JP56031983 A JP 56031983A JP 3198381 A JP3198381 A JP 3198381A JP S57145893 A JPS57145893 A JP S57145893A
Authority
JP
Japan
Prior art keywords
strain
reaction
cultivated
gram
positive
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP56031983A
Other languages
Japanese (ja)
Inventor
Masao Oguchi
Masato Nakayama
Akio Iwasaki
Shigeru Kimura
Toshimi Mizoguchi
Sohei Tanabe
Akira Murakami
Hisakatsu Itou
Toshito Mori
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KOUWA KK
Kowa Co Ltd
Original Assignee
KOUWA KK
Kowa Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by KOUWA KK, Kowa Co Ltd filed Critical KOUWA KK
Priority to JP56031983A priority Critical patent/JPS57145893A/en
Priority to EP81304957A priority patent/EP0050961B1/en
Priority to DE8181304957T priority patent/DE3170632D1/en
Priority to ES506470A priority patent/ES506470A0/en
Priority to US06/314,028 priority patent/US4468350A/en
Priority to AT81304957T priority patent/ATE13431T1/en
Priority to DK469481A priority patent/DK469481A/en
Priority to CA000388574A priority patent/CA1167400A/en
Publication of JPS57145893A publication Critical patent/JPS57145893A/en
Pending legal-status Critical Current

Links

Abstract

NEW MATERIAL:Antibiotic KA-6643-X having the following properties and its salt. Appearance: colorless powder. Molecular weight: measured value, 340.1068, calculated value 340.1090 (as C15H20N2O5S). A molecular formula: C14H19N2O5S.Na. Solubility: soluble in water, methanol, insoluble in acetone, ethyl acetate, chloroform, etc. Color reaction: positive in Ehrlich reaction, and negative in ninhydrin reaction.
USE: Exhibiting antibacterial action of Gram-positive and Gram-negative bacteria, having strong β-lactamase inhibiting action.
PROCESS: N-Methyl-N'-nitro-N-nitrosoguanidine is added to a mold suspension of Streptomyces KC-6643 M-120-165 strain, which is cultivated to give a new mold KC-6643 M-162-175 strain (FERM-P 5890). This strain is cultivated by preferably submerged culture at 3W35°C under aerobic conditions.
COPYRIGHT: (C)1982,JPO&Japio
JP56031983A 1980-10-24 1981-03-06 Antibiotic and its preparation Pending JPS57145893A (en)

Priority Applications (8)

Application Number Priority Date Filing Date Title
JP56031983A JPS57145893A (en) 1981-03-06 1981-03-06 Antibiotic and its preparation
EP81304957A EP0050961B1 (en) 1980-10-24 1981-10-22 Novel antibiotics, a process for producing the same, medical compositions containing the same, and a novel strain of the genus streptomyces for use in producing the same
DE8181304957T DE3170632D1 (en) 1980-10-24 1981-10-22 Novel antibiotics, a process for producing the same, medical compositions containing the same, and a novel strain of the genus streptomyces for use in producing the same
ES506470A ES506470A0 (en) 1980-10-24 1981-10-22 PRODUCTION PROCESS OF A DRUG COMPOUND CONTAINING KA-6643 SERIES ANTIBIOTICS
US06/314,028 US4468350A (en) 1980-10-24 1981-10-22 KA-6643-Series antibiotics, process for producing same and medical composition containing same
AT81304957T ATE13431T1 (en) 1980-10-24 1981-10-22 ANTIBIOTICS, PROCESS FOR THEIR MANUFACTURE, MEDICATIONS CONTAINING THEM AND A STREPTOMYCES SPECIES STRAIN USED FOR THEIR MANUFACTURE.
DK469481A DK469481A (en) 1980-10-24 1981-10-23 PROCEDURE FOR THE MANUFACTURE OF ANTIBIOTICS
CA000388574A CA1167400A (en) 1980-10-24 1981-10-23 Ka-6643-series antibiotics, process for producing same and medical composition containing same

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP56031983A JPS57145893A (en) 1981-03-06 1981-03-06 Antibiotic and its preparation

Publications (1)

Publication Number Publication Date
JPS57145893A true JPS57145893A (en) 1982-09-09

Family

ID=12346164

Family Applications (1)

Application Number Title Priority Date Filing Date
JP56031983A Pending JPS57145893A (en) 1980-10-24 1981-03-06 Antibiotic and its preparation

Country Status (1)

Country Link
JP (1) JPS57145893A (en)

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