JPS57140714A - Medicine containing n-(3,4-dihydroxybenzylidene)- aminomethylcarboxylic acid, salt or ester thereof - Google Patents
Medicine containing n-(3,4-dihydroxybenzylidene)- aminomethylcarboxylic acid, salt or ester thereofInfo
- Publication number
- JPS57140714A JPS57140714A JP56025990A JP2599081A JPS57140714A JP S57140714 A JPS57140714 A JP S57140714A JP 56025990 A JP56025990 A JP 56025990A JP 2599081 A JP2599081 A JP 2599081A JP S57140714 A JPS57140714 A JP S57140714A
- Authority
- JP
- Japan
- Prior art keywords
- ester
- expressed
- dihydroxybenzylidene
- salt
- aminomethylcyclohexane
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000002148 esters Chemical class 0.000 title abstract 3
- 150000003839 salts Chemical class 0.000 title abstract 2
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Natural products NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 title 1
- 229940079593 drug Drugs 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- GYDJEQRTZSCIOI-UHFFFAOYSA-N Tranexamic acid Chemical compound NCC1CCC(C(O)=O)CC1 GYDJEQRTZSCIOI-UHFFFAOYSA-N 0.000 abstract 2
- 201000000596 systemic lupus erythematosus Diseases 0.000 abstract 2
- UXXFHSFSWVPUGY-UHFFFAOYSA-N 4-[[(3,4-dihydroxyphenyl)methylideneamino]methyl]cyclohexane-1-carboxylic acid Chemical compound OC=1C=C(C=NCC2CCC(CC2)C(=O)O)C=CC1O UXXFHSFSWVPUGY-UHFFFAOYSA-N 0.000 abstract 1
- 206010008111 Cerebral haemorrhage Diseases 0.000 abstract 1
- 208000017667 Chronic Disease Diseases 0.000 abstract 1
- 206010020772 Hypertension Diseases 0.000 abstract 1
- 206010061218 Inflammation Diseases 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 208000007536 Thrombosis Diseases 0.000 abstract 1
- 239000013543 active substance Substances 0.000 abstract 1
- 208000006673 asthma Diseases 0.000 abstract 1
- 210000001772 blood platelet Anatomy 0.000 abstract 1
- 230000001684 chronic effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000018044 dehydration Effects 0.000 abstract 1
- 238000006297 dehydration reaction Methods 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000004054 inflammatory process Effects 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 230000001105 regulatory effect Effects 0.000 abstract 1
- 208000010110 spontaneous platelet aggregation Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C249/00—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton
- C07C249/02—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton of compounds containing imino groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
- C07C251/02—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups
- C07C251/24—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups having carbon atoms of imino groups bound to carbon atoms of six-membered aromatic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Priority Applications (9)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP56025990A JPS57140714A (en) | 1981-02-24 | 1981-02-24 | Medicine containing n-(3,4-dihydroxybenzylidene)- aminomethylcarboxylic acid, salt or ester thereof |
US06/267,250 US4382955A (en) | 1980-06-04 | 1981-05-26 | Derivative of 4-(N-(3,4-dihydroxybenzylidene) aminomethyl cyclohexane-1-carboxylic acid |
AU71169/81A AU538938B2 (en) | 1980-06-04 | 1981-05-29 | 4-(n-(3:,4:-dihydroxybenzylidene)aminoethyl)cyclohexane- 1-carboxylic acid |
DE8181302467T DE3162772D1 (de) | 1980-06-04 | 1981-06-03 | A n-(benzylidene) aminomethyl-cyclohexane-carboxylic acid |
CA000378962A CA1183151A (en) | 1980-06-04 | 1981-06-03 | Derivative of 4-[n-(3',4'- dihydroxybenzylidene)aminomethyl]cyclohexane-1- carboxylic acid |
EP81302467A EP0041827B1 (en) | 1980-06-04 | 1981-06-03 | A n-(benzylidene) aminomethyl-cyclohexane-carboxylic acid |
NO811888A NO152253C (no) | 1980-06-04 | 1981-06-03 | Analogifremgangsmaate for fremstlling av 4-(n-(3`,4`-dihydroksybenzyliden)aminometyl)-cykloheksan-1-karboksylsyre med terapeutisk aktivitet |
DK248081A DK152649C (da) | 1980-06-04 | 1981-06-04 | Analogifremgangsmaade til fremstilling af en 4-oen-(3',4'-dihydroxybenzyliden)-aminomethylaacyklohexan-1-carboxylsyre og derivater deraf |
KR1019810003286A KR860000998B1 (ko) | 1981-02-24 | 1981-09-03 | 4-[n-(3',4'-디하이드록시벤질리덴)아미노메틸] 사이클로헥산-1-카복실산 유도체의 제조방법 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP56025990A JPS57140714A (en) | 1981-02-24 | 1981-02-24 | Medicine containing n-(3,4-dihydroxybenzylidene)- aminomethylcarboxylic acid, salt or ester thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS57140714A true JPS57140714A (en) | 1982-08-31 |
JPH0140805B2 JPH0140805B2 (enrdf_load_stackoverflow) | 1989-08-31 |
Family
ID=12181145
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP56025990A Granted JPS57140714A (en) | 1980-06-04 | 1981-02-24 | Medicine containing n-(3,4-dihydroxybenzylidene)- aminomethylcarboxylic acid, salt or ester thereof |
Country Status (2)
Country | Link |
---|---|
JP (1) | JPS57140714A (enrdf_load_stackoverflow) |
KR (1) | KR860000998B1 (enrdf_load_stackoverflow) |
-
1981
- 1981-02-24 JP JP56025990A patent/JPS57140714A/ja active Granted
- 1981-09-03 KR KR1019810003286A patent/KR860000998B1/ko not_active Expired
Also Published As
Publication number | Publication date |
---|---|
KR830008550A (ko) | 1983-12-10 |
JPH0140805B2 (enrdf_load_stackoverflow) | 1989-08-31 |
KR860000998B1 (ko) | 1986-07-26 |
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