JPS57134467A - Pyridine derivative and its preparation - Google Patents

Pyridine derivative and its preparation

Info

Publication number
JPS57134467A
JPS57134467A JP1990381A JP1990381A JPS57134467A JP S57134467 A JPS57134467 A JP S57134467A JP 1990381 A JP1990381 A JP 1990381A JP 1990381 A JP1990381 A JP 1990381A JP S57134467 A JPS57134467 A JP S57134467A
Authority
JP
Japan
Prior art keywords
alkyl
formula
preparation
alkoxycarbonyl
alkylthio
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP1990381A
Other languages
Japanese (ja)
Other versions
JPS6326759B2 (en
Inventor
Sadakatsu Shimada
Masanobu Oki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Daiichi Pharmaceutical Co Ltd
Original Assignee
Daiichi Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiichi Pharmaceutical Co Ltd filed Critical Daiichi Pharmaceutical Co Ltd
Priority to JP1990381A priority Critical patent/JPS57134467A/en
Publication of JPS57134467A publication Critical patent/JPS57134467A/en
Publication of JPS6326759B2 publication Critical patent/JPS6326759B2/ja
Granted legal-status Critical Current

Links

Abstract

PURPOSE: To prepare the titled compounds including novel substances useful as intermediates for the preparation of vitamin B6, etc., easily, by using a specific 1,2,4-triazine derivative as a raw material, and reacting with an olefin.
CONSTITUTION: A 1,2,4-triazine derivative of formulaI(R1 is a group convertible to carboxylic acid group, e.g. H, alkyl, amino, alkoxy, alkylthio, aryl, carboxyl, alkoxycarbonyl, cyano, etc.; R2 and R3 are H, alkyl, amino, alkoxy, alkylthio, or aryl) is made to react with an olefin of formula II[A and B are cyano, carboxyl, alkoxycarbonyl, halogenocarbonyl, formyl, or carbamoyl, or A and B together form -COOCO-, -COSCO- or heterocyclic group of formula IV or formula V (R4 and R5 are alkyl)]to obtain a pyridine derivative of formula III (when R1 is as defined above excepting alkyl, and R2 and R3 are not H at the same time, the compound is novel substance).
COPYRIGHT: (C)1982,JPO&Japio
JP1990381A 1981-02-13 1981-02-13 Pyridine derivative and its preparation Granted JPS57134467A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP1990381A JPS57134467A (en) 1981-02-13 1981-02-13 Pyridine derivative and its preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP1990381A JPS57134467A (en) 1981-02-13 1981-02-13 Pyridine derivative and its preparation

Publications (2)

Publication Number Publication Date
JPS57134467A true JPS57134467A (en) 1982-08-19
JPS6326759B2 JPS6326759B2 (en) 1988-05-31

Family

ID=12012160

Family Applications (1)

Application Number Title Priority Date Filing Date
JP1990381A Granted JPS57134467A (en) 1981-02-13 1981-02-13 Pyridine derivative and its preparation

Country Status (1)

Country Link
JP (1) JPS57134467A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000076975A1 (en) * 1999-06-14 2000-12-21 Sankio Chemical Co., Ltd. Process for the production of 2-pyridylpyridine derivatives
WO2011087776A1 (en) * 2009-12-22 2011-07-21 Vertex Pharmaceuticals Incorporated Isoindolinone inhibitors of phosphatidylinositol 3-kinase

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000076975A1 (en) * 1999-06-14 2000-12-21 Sankio Chemical Co., Ltd. Process for the production of 2-pyridylpyridine derivatives
US6504032B1 (en) 1999-06-14 2003-01-07 Sankio Chemical Co., Ltd. Process for the production of 2-pyridylpyridine derivatives
WO2011087776A1 (en) * 2009-12-22 2011-07-21 Vertex Pharmaceuticals Incorporated Isoindolinone inhibitors of phosphatidylinositol 3-kinase
US8466288B2 (en) 2009-12-22 2013-06-18 Vertex Pharmaceuticals Incorporated Isoindolinone inhibitors of phosphatidylinositol 3-kinase
US9676759B2 (en) 2009-12-22 2017-06-13 Vertex Pharmaceuticals Incorporated Isoindolinone inhibitors of phosphatidylinositol 3-kinase
EP3309152A1 (en) * 2009-12-22 2018-04-18 Vertex Pharmaceuticals Incorporated Isoindolinone inhibitors of phosphatidylinositol 3-kinase
US10183933B2 (en) 2009-12-22 2019-01-22 Vertex Pharmaceuticals Incorporated Isoindolinone inhibitors of phosphatidylinositol 3-kinase
EP3808739A1 (en) * 2009-12-22 2021-04-21 Vertex Pharmaceuticals Incorporated Isoindolinone inhibitors of phosphatidylinositol 3-kinase

Also Published As

Publication number Publication date
JPS6326759B2 (en) 1988-05-31

Similar Documents

Publication Publication Date Title
JPS56131565A (en) 4-substituted-2-oxoazetidine compound and its preparation
JPS57134467A (en) Pyridine derivative and its preparation
JPS55380A (en) Preparation of dibenzoxepin derivative
JPS57167902A (en) Herbicidal composition
JPS5759897A (en) Thiazolineazatidinone
JPS57139065A (en) Preparation of omega-indole-3-ylalkanole compound
JPS57112352A (en) Preparation of phenylacetic acid alkyl ester
JPS57183758A (en) Preparation of (n-methylpyrrol-2-)acetothioamide derivative
JPS5793981A (en) Carba-2-penem compound and its preparation
JPS5668668A (en) Preparation of 2-indolinones
JPS5738780A (en) Emetine type compound and its preparation
JPS5432480A (en) Novel preparation of piperidine derivatives
JPS5531072A (en) Preparation of 2-pyridone compound
JPS549225A (en) Preparation of hydrazinoalkanesulfonic acid derivatives
JPS5735573A (en) Novel 3-alkyl substituted 2,4(1h,3h)-quinazolinedione derivative
JPS56127334A (en) Preparation of 2-oxo-5-vinylcyclopentanecarboxylic ester and its 1-alkyl substitution product
JPS5231059A (en) Preparation of oxybenzoylbenzoic acids
JPS5756482A (en) Ampicillin ester and its preparation
JPS57206688A (en) Thiazolinotriazine derivative and fungicide for agriculture and gardening
JPS57126477A (en) Preparation of nicotinic acid derivative
JPS5473797A (en) Pyride 3.2.1-jk carbazole derivative
JPS56133220A (en) Preparation of aldehyde
JPS5726660A (en) Novel beta-lactam compound and its preparation
JPS5538361A (en) 6-hydroxymethylpyrido 2,3-d pyrimidine derivative and its preparation
JPS5679668A (en) 1,4-dihydro-4-oxonicotinic acid derivatice and its preparation