JPS57118598A - Istamycin c or co and preparation thereof - Google Patents

Istamycin c or co and preparation thereof

Info

Publication number
JPS57118598A
JPS57118598A JP56003849A JP384981A JPS57118598A JP S57118598 A JPS57118598 A JP S57118598A JP 56003849 A JP56003849 A JP 56003849A JP 384981 A JP384981 A JP 384981A JP S57118598 A JPS57118598 A JP S57118598A
Authority
JP
Japan
Prior art keywords
istamycin
istamycins
strain
positive
substance
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP56003849A
Other languages
Japanese (ja)
Inventor
Hamao Umezawa
Yoshiro Okami
Shinichi Kondo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Microbial Chemistry Research Foundation
Original Assignee
Microbial Chemistry Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Microbial Chemistry Research Foundation filed Critical Microbial Chemistry Research Foundation
Priority to JP56003849A priority Critical patent/JPS57118598A/en
Publication of JPS57118598A publication Critical patent/JPS57118598A/en
Pending legal-status Critical Current

Links

Classifications

    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:An antibiotic substance istamycin A (acid addition salt) of formulaIhaving the following properties: (l) Basic substance. Its carbonate is white powder. (2) Exhibits no definite melting point. (3) Specific rotatory power: [α]D25=+131° (C=1.0, water). (4) Soluble in methanol, and slightly soluble in ethanol. (5) Positive to the ninhydrin and Rydon-Smith reactions.
USE: An antimicrobial agent against Gram-positive and Gram-negative bacteria.
PROCESS: A strain, e.g. Streptomyces tenjimariensis-SS939 strain (FEMR-P No. 4932), of the genus Streptomyces, is cultivated, and istamycins C and CO are collected with istamycins A and B which are principal components in the culture fluid. The resultant istamycins C and CO are then purified and separated. The istamycin CO is a novel substance, expressed by formula II or III, and having a weak antimicrobial activity thereof, but can be easily converted into the istamycin C (by converting the methylamino group at 4-position into an N-glycyl group).
COPYRIGHT: (C)1982,JPO&Japio
JP56003849A 1981-01-16 1981-01-16 Istamycin c or co and preparation thereof Pending JPS57118598A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP56003849A JPS57118598A (en) 1981-01-16 1981-01-16 Istamycin c or co and preparation thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP56003849A JPS57118598A (en) 1981-01-16 1981-01-16 Istamycin c or co and preparation thereof

Publications (1)

Publication Number Publication Date
JPS57118598A true JPS57118598A (en) 1982-07-23

Family

ID=11568626

Family Applications (1)

Application Number Title Priority Date Filing Date
JP56003849A Pending JPS57118598A (en) 1981-01-16 1981-01-16 Istamycin c or co and preparation thereof

Country Status (1)

Country Link
JP (1) JPS57118598A (en)

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