JPS5697248A - Conjugated compound of calcium citrate and calcium malate and its preparation - Google Patents
Conjugated compound of calcium citrate and calcium malate and its preparationInfo
- Publication number
- JPS5697248A JPS5697248A JP17317279A JP17317279A JPS5697248A JP S5697248 A JPS5697248 A JP S5697248A JP 17317279 A JP17317279 A JP 17317279A JP 17317279 A JP17317279 A JP 17317279A JP S5697248 A JPS5697248 A JP S5697248A
- Authority
- JP
- Japan
- Prior art keywords
- calcium
- malate
- citrate
- water
- conjugated compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- FNAQSUUGMSOBHW-UHFFFAOYSA-H calcium citrate Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O.[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O FNAQSUUGMSOBHW-UHFFFAOYSA-H 0.000 title abstract 5
- 239000001354 calcium citrate Substances 0.000 title abstract 5
- 235000013337 tricalcium citrate Nutrition 0.000 title abstract 5
- 239000001362 calcium malate Substances 0.000 title abstract 4
- OLOZVPHKXALCRI-UHFFFAOYSA-L calcium malate Chemical compound [Ca+2].[O-]C(=O)C(O)CC([O-])=O OLOZVPHKXALCRI-UHFFFAOYSA-L 0.000 title abstract 4
- 229940016114 calcium malate Drugs 0.000 title abstract 4
- 235000011038 calcium malates Nutrition 0.000 title abstract 4
- 150000001875 compounds Chemical class 0.000 title abstract 3
- 229940092124 calcium citrate malate Drugs 0.000 title 1
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 abstract 3
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 abstract 2
- 235000013305 food Nutrition 0.000 abstract 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 2
- BJEPYKJPYRNKOW-REOHCLBHSA-N (S)-malic acid Chemical compound OC(=O)[C@@H](O)CC(O)=O BJEPYKJPYRNKOW-REOHCLBHSA-N 0.000 abstract 1
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 abstract 1
- UXVMQQNJUSDDNG-UHFFFAOYSA-L Calcium chloride Chemical compound [Cl-].[Cl-].[Ca+2] UXVMQQNJUSDDNG-UHFFFAOYSA-L 0.000 abstract 1
- 240000007594 Oryza sativa Species 0.000 abstract 1
- 235000007164 Oryza sativa Nutrition 0.000 abstract 1
- BJEPYKJPYRNKOW-UHFFFAOYSA-N alpha-hydroxysuccinic acid Natural products OC(=O)C(O)CC(O)=O BJEPYKJPYRNKOW-UHFFFAOYSA-N 0.000 abstract 1
- 239000011575 calcium Substances 0.000 abstract 1
- 229910052791 calcium Inorganic materials 0.000 abstract 1
- 229910000019 calcium carbonate Inorganic materials 0.000 abstract 1
- 239000001110 calcium chloride Substances 0.000 abstract 1
- 229910001628 calcium chloride Inorganic materials 0.000 abstract 1
- AXCZMVOFGPJBDE-UHFFFAOYSA-L calcium dihydroxide Chemical compound [OH-].[OH-].[Ca+2] AXCZMVOFGPJBDE-UHFFFAOYSA-L 0.000 abstract 1
- 239000000920 calcium hydroxide Substances 0.000 abstract 1
- 229910001861 calcium hydroxide Inorganic materials 0.000 abstract 1
- WPUMTJGUQUYPIV-JIZZDEOASA-L disodium (S)-malate Chemical compound [Na+].[Na+].[O-]C(=O)[C@@H](O)CC([O-])=O WPUMTJGUQUYPIV-JIZZDEOASA-L 0.000 abstract 1
- 239000001630 malic acid Substances 0.000 abstract 1
- 235000011090 malic acid Nutrition 0.000 abstract 1
- 230000000050 nutritive effect Effects 0.000 abstract 1
- 235000009566 rice Nutrition 0.000 abstract 1
- 235000019265 sodium DL-malate Nutrition 0.000 abstract 1
- 239000001509 sodium citrate Substances 0.000 abstract 1
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 abstract 1
- 239000001394 sodium malate Substances 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Landscapes
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP17317279A JPS5697248A (en) | 1979-12-28 | 1979-12-28 | Conjugated compound of calcium citrate and calcium malate and its preparation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP17317279A JPS5697248A (en) | 1979-12-28 | 1979-12-28 | Conjugated compound of calcium citrate and calcium malate and its preparation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS5697248A true JPS5697248A (en) | 1981-08-05 |
| JPH0448421B2 JPH0448421B2 (enrdf_load_stackoverflow) | 1992-08-06 |
Family
ID=15955419
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP17317279A Granted JPS5697248A (en) | 1979-12-28 | 1979-12-28 | Conjugated compound of calcium citrate and calcium malate and its preparation |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS5697248A (enrdf_load_stackoverflow) |
Cited By (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4551342A (en) * | 1983-02-01 | 1985-11-05 | The Procter & Gamble Company | Beverages containing specific cation-edible acid mixtures for improved flavor impression |
| US4737375A (en) * | 1985-12-26 | 1988-04-12 | The Procter & Gamble Company | Beverages and beverage concentrates nutritionally supplemented with calcium |
| JPS6480261A (en) * | 1987-07-02 | 1989-03-27 | Procter & Gamble | Calcium-ferrous mineral feed product |
| JPH01151515A (ja) * | 1987-08-28 | 1989-06-14 | Norwich Eaton Pharmaceut Inc | 骨粗鬆症および関連障害の治療法 |
| US4992282A (en) * | 1989-05-08 | 1991-02-12 | The Procter & Gamble Company | Stable nutritional vitamin and mineral supplemented beverage |
| US5128374A (en) * | 1987-08-28 | 1992-07-07 | The Procter & Gamble Company | Use of calcium citrate malate for the treatment of osteoporosis and related disorders |
| US5186965A (en) * | 1990-06-14 | 1993-02-16 | The Procter & Gamble Company | Calcium citrate malate composition |
| US5215769A (en) * | 1990-10-31 | 1993-06-01 | The Procter & Gamble Company | Calcium fortified dressing salad product |
| US5232709A (en) * | 1990-08-06 | 1993-08-03 | The Procter & Gamble Company | Calcium and trace mineral supplements comprising estrogen |
| US5314919A (en) * | 1987-08-28 | 1994-05-24 | The Procter & Gamble Company | Calcium supplements |
| US5389387A (en) * | 1991-12-26 | 1995-02-14 | The Procter & Gamble Company | Storage stable calcium-supplemented beverage concentrates |
| US5401524A (en) * | 1992-10-21 | 1995-03-28 | The Proctor & Gamble Company | Storage stable calcium-supplemented beverage premix concentrates and syrups |
| US5422128A (en) * | 1991-12-26 | 1995-06-06 | The Procter & Gamble Company | Storage stable calcium-supplemented beverage concentrates |
| US5445837A (en) * | 1992-10-21 | 1995-08-29 | The Procter & Gamble Company | Sweetener supplement fortified with a concentrated bioavailable calcium source and process of making |
| US5468506A (en) * | 1992-10-21 | 1995-11-21 | The Procter & Gamble Company | Concentrated bioavailable calcium source |
| US5516535A (en) * | 1992-11-19 | 1996-05-14 | The Procter & Gamble | Beverage compositions having enhanced β-carotene bioavailability |
| EP0719783A2 (en) | 1994-08-11 | 1996-07-03 | Ezaki Glico Co., Ltd. | Phosphorylated saccharide and method for producing the same |
| US6080431A (en) * | 1991-05-06 | 2000-06-27 | The Procter & Gamble Company | Combined calcium and vitamin supplements for bone growth |
| US6811800B2 (en) | 1998-09-29 | 2004-11-02 | The Procter & Gamble Co. | Calcium fortified beverages |
| WO2007072756A1 (ja) | 2005-12-19 | 2007-06-28 | Matsutani Chemical Industry Co. Ltd. | ミネラル吸収促進剤、食品及び飼料 |
| JP2007520219A (ja) * | 2004-02-02 | 2007-07-26 | デラボー エル．エル．シー． | パン生地のカルシウム強化 |
| US7504536B2 (en) | 2006-08-17 | 2009-03-17 | The Procter & Gamble Company | Compositions comprising calcium citrate malate and methods for making the same |
| JP2010500877A (ja) * | 2006-08-17 | 2010-01-14 | ザ プロクター アンド ギャンブル カンパニー | クエン酸リンゴ酸カルシウムを含む組成物及びその製造方法 |
| JPWO2009011288A1 (ja) * | 2007-07-13 | 2010-09-24 | 株式会社メニコン | カルシウムイオン徐放剤 |
| US7927640B2 (en) | 2004-02-02 | 2011-04-19 | Delavau Llc | Calcium fortification of bread dough |
| US8911805B2 (en) | 2010-03-31 | 2014-12-16 | Toyo Suisan Kaisha, Ltd. | Calcium preparation and method of production thereof |
| US10624879B2 (en) | 2014-03-19 | 2020-04-21 | Ferring International Center S.A. | Liquid pharmaceutical composition |
| US11612592B2 (en) | 2015-08-17 | 2023-03-28 | Ferring B.V. | Liquid formulations containing picosulfate and magnesium citrate |
-
1979
- 1979-12-28 JP JP17317279A patent/JPS5697248A/ja active Granted
Cited By (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4551342A (en) * | 1983-02-01 | 1985-11-05 | The Procter & Gamble Company | Beverages containing specific cation-edible acid mixtures for improved flavor impression |
| US4737375A (en) * | 1985-12-26 | 1988-04-12 | The Procter & Gamble Company | Beverages and beverage concentrates nutritionally supplemented with calcium |
| JPS6480261A (en) * | 1987-07-02 | 1989-03-27 | Procter & Gamble | Calcium-ferrous mineral feed product |
| EP0297679A3 (en) * | 1987-07-02 | 1989-10-18 | The Procter & Gamble Company | Calcium-iron mineral supplements |
| US5314919A (en) * | 1987-08-28 | 1994-05-24 | The Procter & Gamble Company | Calcium supplements |
| JPH01151515A (ja) * | 1987-08-28 | 1989-06-14 | Norwich Eaton Pharmaceut Inc | 骨粗鬆症および関連障害の治療法 |
| US5128374A (en) * | 1987-08-28 | 1992-07-07 | The Procter & Gamble Company | Use of calcium citrate malate for the treatment of osteoporosis and related disorders |
| US4992282A (en) * | 1989-05-08 | 1991-02-12 | The Procter & Gamble Company | Stable nutritional vitamin and mineral supplemented beverage |
| US5186965A (en) * | 1990-06-14 | 1993-02-16 | The Procter & Gamble Company | Calcium citrate malate composition |
| US5232709A (en) * | 1990-08-06 | 1993-08-03 | The Procter & Gamble Company | Calcium and trace mineral supplements comprising estrogen |
| US5215769A (en) * | 1990-10-31 | 1993-06-01 | The Procter & Gamble Company | Calcium fortified dressing salad product |
| US6080431A (en) * | 1991-05-06 | 2000-06-27 | The Procter & Gamble Company | Combined calcium and vitamin supplements for bone growth |
| US5389387A (en) * | 1991-12-26 | 1995-02-14 | The Procter & Gamble Company | Storage stable calcium-supplemented beverage concentrates |
| US5422128A (en) * | 1991-12-26 | 1995-06-06 | The Procter & Gamble Company | Storage stable calcium-supplemented beverage concentrates |
| US5401524A (en) * | 1992-10-21 | 1995-03-28 | The Proctor & Gamble Company | Storage stable calcium-supplemented beverage premix concentrates and syrups |
| US5445837A (en) * | 1992-10-21 | 1995-08-29 | The Procter & Gamble Company | Sweetener supplement fortified with a concentrated bioavailable calcium source and process of making |
| US5468506A (en) * | 1992-10-21 | 1995-11-21 | The Procter & Gamble Company | Concentrated bioavailable calcium source |
| US5516535A (en) * | 1992-11-19 | 1996-05-14 | The Procter & Gamble | Beverage compositions having enhanced β-carotene bioavailability |
| US6268182B1 (en) | 1994-08-11 | 2001-07-31 | Ezaki Glico Co., Ltd. | Method and producing phosphorylated saccharides |
| US5861048A (en) * | 1994-08-11 | 1999-01-19 | Ezaki Glico Co., Ltd. | Phosphorylated saccharide and method for producing the same |
| EP0719783A2 (en) | 1994-08-11 | 1996-07-03 | Ezaki Glico Co., Ltd. | Phosphorylated saccharide and method for producing the same |
| US6811800B2 (en) | 1998-09-29 | 2004-11-02 | The Procter & Gamble Co. | Calcium fortified beverages |
| US6994877B2 (en) | 1998-09-29 | 2006-02-07 | The Procter + Gamble Co. | Calcium fortified beverages |
| US9386776B2 (en) | 2004-02-02 | 2016-07-12 | Delavau L.L.C. | Calcium fortification of bread dough |
| JP2007520219A (ja) * | 2004-02-02 | 2007-07-26 | デラボー エル．エル．シー． | パン生地のカルシウム強化 |
| US7927640B2 (en) | 2004-02-02 | 2011-04-19 | Delavau Llc | Calcium fortification of bread dough |
| US8221808B2 (en) | 2004-02-02 | 2012-07-17 | Delavau L.L.C. | Calcium fortification of bread dough |
| WO2007072756A1 (ja) | 2005-12-19 | 2007-06-28 | Matsutani Chemical Industry Co. Ltd. | ミネラル吸収促進剤、食品及び飼料 |
| US7504536B2 (en) | 2006-08-17 | 2009-03-17 | The Procter & Gamble Company | Compositions comprising calcium citrate malate and methods for making the same |
| JP2010500990A (ja) * | 2006-08-17 | 2010-01-14 | ザ プロクター アンド ギャンブル カンパニー | クエン酸リンゴ酸カルシウムを含む組成物及びその製造方法 |
| JP2010500877A (ja) * | 2006-08-17 | 2010-01-14 | ザ プロクター アンド ギャンブル カンパニー | クエン酸リンゴ酸カルシウムを含む組成物及びその製造方法 |
| US8889195B2 (en) | 2006-08-17 | 2014-11-18 | The Procter & Gamble Company | Compositions comprising calcium citrate malate and methods for making the same |
| JP2011142920A (ja) * | 2006-08-17 | 2011-07-28 | Procter & Gamble Co | クエン酸リンゴ酸カルシウムを含む組成物及びその製造方法 |
| JP4580034B2 (ja) * | 2007-07-13 | 2010-11-10 | 株式会社メニコン | カルシウムイオン徐放剤 |
| JPWO2009011288A1 (ja) * | 2007-07-13 | 2010-09-24 | 株式会社メニコン | カルシウムイオン徐放剤 |
| US8911805B2 (en) | 2010-03-31 | 2014-12-16 | Toyo Suisan Kaisha, Ltd. | Calcium preparation and method of production thereof |
| EP2561878A4 (en) * | 2010-03-31 | 2016-05-25 | Toyo Suisan Kaisha | CALCIUM PREPARATION AND METHOD FOR THE PRODUCTION THEREOF |
| US10624879B2 (en) | 2014-03-19 | 2020-04-21 | Ferring International Center S.A. | Liquid pharmaceutical composition |
| US11191753B2 (en) | 2014-03-19 | 2021-12-07 | Ferring International Center Sa. | Liquid pharmaceutical composition |
| US11612592B2 (en) | 2015-08-17 | 2023-03-28 | Ferring B.V. | Liquid formulations containing picosulfate and magnesium citrate |
Also Published As
| Publication number | Publication date |
|---|---|
| JPH0448421B2 (enrdf_load_stackoverflow) | 1992-08-06 |
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