JPS5679674A - Preparation of amino group-containing pyrimidine derivative - Google Patents
Preparation of amino group-containing pyrimidine derivativeInfo
- Publication number
- JPS5679674A JPS5679674A JP15561579A JP15561579A JPS5679674A JP S5679674 A JPS5679674 A JP S5679674A JP 15561579 A JP15561579 A JP 15561579A JP 15561579 A JP15561579 A JP 15561579A JP S5679674 A JPS5679674 A JP S5679674A
- Authority
- JP
- Japan
- Prior art keywords
- group
- formula
- amino
- dehydrating agent
- pyrimidine derivative
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
PURPOSE: To prepare the titled compound by one step useful as a drug, e.g., corona dilator, agricultural chemical, photographic agent, etc., by reacting a keto amide readily obtainable from the reaction of diketene and a secondary amine with an mine in the presence of a dehydrating agent.
CONSTITUTION: An amino compound (e.g., 3-amino-1,2,4-triazole, etc.) shown by the formula I (X is monofunctional group; Y is bifunctional group; X may be connected to Y) or shown by the formula II (Z is monofunctional group) is reacted with a keto amide (e.g., N,N-diethylacetoacetic amide, etc.) shown by the formula III (R1, R3, and R4 are hydrocarbon group; R2 is H or hydrocarbon group) in the presence of a dehydrating agent, e.g., phosphorus oxychloride, etc. to give an amino group-containing pyrimidine derivative [e.g., 7-diethylamino-5-methyl-S-triazolo[1, 5-a]pyrimidine, etc.] shown by the formula IV or V. An amount of the dehydrating agent is preferably 5W10mol based on 1mol of one of the raw materials, which is used in smaller ratio.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP15561579A JPS5679674A (en) | 1979-12-03 | 1979-12-03 | Preparation of amino group-containing pyrimidine derivative |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP15561579A JPS5679674A (en) | 1979-12-03 | 1979-12-03 | Preparation of amino group-containing pyrimidine derivative |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS5679674A true JPS5679674A (en) | 1981-06-30 |
Family
ID=15609882
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP15561579A Pending JPS5679674A (en) | 1979-12-03 | 1979-12-03 | Preparation of amino group-containing pyrimidine derivative |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5679674A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS59155370A (en) * | 1983-01-07 | 1984-09-04 | ロリス・ヤコポ・ボノニ | Aminoalkylsulfonic acid derivative, manufacture and antiviral |
-
1979
- 1979-12-03 JP JP15561579A patent/JPS5679674A/en active Pending
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS59155370A (en) * | 1983-01-07 | 1984-09-04 | ロリス・ヤコポ・ボノニ | Aminoalkylsulfonic acid derivative, manufacture and antiviral |
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