JPS5679674A - Preparation of amino group-containing pyrimidine derivative - Google Patents

Preparation of amino group-containing pyrimidine derivative

Info

Publication number
JPS5679674A
JPS5679674A JP15561579A JP15561579A JPS5679674A JP S5679674 A JPS5679674 A JP S5679674A JP 15561579 A JP15561579 A JP 15561579A JP 15561579 A JP15561579 A JP 15561579A JP S5679674 A JPS5679674 A JP S5679674A
Authority
JP
Japan
Prior art keywords
group
formula
amino
dehydrating agent
pyrimidine derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP15561579A
Other languages
Japanese (ja)
Inventor
Yoshiro Furuya
Noriaki Kihara
Tatsukazu Ishida
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsui Petrochemical Industries Ltd
Original Assignee
Mitsui Petrochemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsui Petrochemical Industries Ltd filed Critical Mitsui Petrochemical Industries Ltd
Priority to JP15561579A priority Critical patent/JPS5679674A/en
Publication of JPS5679674A publication Critical patent/JPS5679674A/en
Pending legal-status Critical Current

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  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

PURPOSE: To prepare the titled compound by one step useful as a drug, e.g., corona dilator, agricultural chemical, photographic agent, etc., by reacting a keto amide readily obtainable from the reaction of diketene and a secondary amine with an mine in the presence of a dehydrating agent.
CONSTITUTION: An amino compound (e.g., 3-amino-1,2,4-triazole, etc.) shown by the formula I (X is monofunctional group; Y is bifunctional group; X may be connected to Y) or shown by the formula II (Z is monofunctional group) is reacted with a keto amide (e.g., N,N-diethylacetoacetic amide, etc.) shown by the formula III (R1, R3, and R4 are hydrocarbon group; R2 is H or hydrocarbon group) in the presence of a dehydrating agent, e.g., phosphorus oxychloride, etc. to give an amino group-containing pyrimidine derivative [e.g., 7-diethylamino-5-methyl-S-triazolo[1, 5-a]pyrimidine, etc.] shown by the formula IV or V. An amount of the dehydrating agent is preferably 5W10mol based on 1mol of one of the raw materials, which is used in smaller ratio.
COPYRIGHT: (C)1981,JPO&Japio
JP15561579A 1979-12-03 1979-12-03 Preparation of amino group-containing pyrimidine derivative Pending JPS5679674A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP15561579A JPS5679674A (en) 1979-12-03 1979-12-03 Preparation of amino group-containing pyrimidine derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP15561579A JPS5679674A (en) 1979-12-03 1979-12-03 Preparation of amino group-containing pyrimidine derivative

Publications (1)

Publication Number Publication Date
JPS5679674A true JPS5679674A (en) 1981-06-30

Family

ID=15609882

Family Applications (1)

Application Number Title Priority Date Filing Date
JP15561579A Pending JPS5679674A (en) 1979-12-03 1979-12-03 Preparation of amino group-containing pyrimidine derivative

Country Status (1)

Country Link
JP (1) JPS5679674A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59155370A (en) * 1983-01-07 1984-09-04 ロリス・ヤコポ・ボノニ Aminoalkylsulfonic acid derivative, manufacture and antiviral

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59155370A (en) * 1983-01-07 1984-09-04 ロリス・ヤコポ・ボノニ Aminoalkylsulfonic acid derivative, manufacture and antiviral

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