JPS57126457A - Novel benzanilide derivative - Google Patents

Novel benzanilide derivative

Info

Publication number
JPS57126457A
JPS57126457A JP1013581A JP1013581A JPS57126457A JP S57126457 A JPS57126457 A JP S57126457A JP 1013581 A JP1013581 A JP 1013581A JP 1013581 A JP1013581 A JP 1013581A JP S57126457 A JPS57126457 A JP S57126457A
Authority
JP
Japan
Prior art keywords
compound
formulai
methoxy
reaction
formula iii
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP1013581A
Other languages
Japanese (ja)
Inventor
Takiyuki Hirayama
Katsuichi Shudo
Masao Naruse
Chihiro Hayashi
Akira Murata
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KH Neochem Co Ltd
Original Assignee
Kyowa Hakko Kogyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyowa Hakko Kogyo Co Ltd filed Critical Kyowa Hakko Kogyo Co Ltd
Priority to JP1013581A priority Critical patent/JPS57126457A/en
Priority to EP82300377A priority patent/EP0058009A1/en
Publication of JPS57126457A publication Critical patent/JPS57126457A/en
Pending legal-status Critical Current

Links

Landscapes

  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

NEW MATERIAL:A compound of formulaI(R1 is F, CF3; R2 is H, halogen, CF3) and its salt.
EXAMPLE: 3-Amino-3'-fluoro-4-methoxy-benzanilide.
USE: Anti-inflammatory, analgesic: it is weak in acute toxicity.
PREPARATION: For example, the reaction of 2-methoxy-5-carboxynitrobenzene with an aniline derivative of formula II gives a compound of formula III. The reaction is effected in a solvent such as toluene in the presence of a condensation reagent such as phosphorus oxychloride. Then, the compound of formula III is reduced to give the compound of formulaI.
COPYRIGHT: (C)1982,JPO&Japio
JP1013581A 1981-01-28 1981-01-28 Novel benzanilide derivative Pending JPS57126457A (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP1013581A JPS57126457A (en) 1981-01-28 1981-01-28 Novel benzanilide derivative
EP82300377A EP0058009A1 (en) 1981-01-28 1982-01-26 Novel benzanilide derivatives and pharmaceutical compositions containing them

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP1013581A JPS57126457A (en) 1981-01-28 1981-01-28 Novel benzanilide derivative

Publications (1)

Publication Number Publication Date
JPS57126457A true JPS57126457A (en) 1982-08-06

Family

ID=11741837

Family Applications (1)

Application Number Title Priority Date Filing Date
JP1013581A Pending JPS57126457A (en) 1981-01-28 1981-01-28 Novel benzanilide derivative

Country Status (1)

Country Link
JP (1) JPS57126457A (en)

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