JPS5661318A - Cembranolide diterpen - Google Patents
Cembranolide diterpenInfo
- Publication number
- JPS5661318A JPS5661318A JP13843079A JP13843079A JPS5661318A JP S5661318 A JPS5661318 A JP S5661318A JP 13843079 A JP13843079 A JP 13843079A JP 13843079 A JP13843079 A JP 13843079A JP S5661318 A JPS5661318 A JP S5661318A
- Authority
- JP
- Japan
- Prior art keywords
- give
- cembranolide
- sarcophytol
- acetyl
- solvent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- DFVBARBOGQRBPH-UAUIHIKDSA-N cembranolide Chemical compound C1\C(C)=C\CCC(/C)=C/CCC2(C)OC2CC2C(=C)C(=O)OC12 DFVBARBOGQRBPH-UAUIHIKDSA-N 0.000 title abstract 2
- 229930192584 cembranolide Natural products 0.000 title abstract 2
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 abstract 3
- HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 abstract 2
- YADVRLOQIWILGX-MIWLTHJTSA-N Sarcophytol A Chemical compound CC(C)C/1=C/C=C(C)/CC\C=C(C)\CC\C=C(C)\C[C@@H]\1O YADVRLOQIWILGX-MIWLTHJTSA-N 0.000 abstract 2
- 125000000218 acetic acid group Chemical group C(C)(=O)* 0.000 abstract 2
- 239000000287 crude extract Substances 0.000 abstract 2
- YADVRLOQIWILGX-UHFFFAOYSA-N sarcophytol N Natural products CC(C)C1=CC=C(C)CCC=C(C)CCC=C(C)CC1O YADVRLOQIWILGX-UHFFFAOYSA-N 0.000 abstract 2
- 239000002904 solvent Substances 0.000 abstract 2
- UCTWMZQNUQWSLP-VIFPVBQESA-N (R)-adrenaline Chemical compound CNC[C@H](O)C1=CC=C(O)C(O)=C1 UCTWMZQNUQWSLP-VIFPVBQESA-N 0.000 abstract 1
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 abstract 1
- 235000014653 Carica parviflora Nutrition 0.000 abstract 1
- 241000243321 Cnidaria Species 0.000 abstract 1
- 241000512743 Sarcophyton <anthozoan> Species 0.000 abstract 1
- 239000003905 agrochemical Substances 0.000 abstract 1
- 230000000719 anti-leukaemic effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 150000002632 lipids Chemical class 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 230000003647 oxidation Effects 0.000 abstract 1
- 238000007254 oxidation reaction Methods 0.000 abstract 1
- 238000010898 silica gel chromatography Methods 0.000 abstract 1
Landscapes
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP13843079A JPS5661318A (en) | 1979-10-26 | 1979-10-26 | Cembranolide diterpen |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP13843079A JPS5661318A (en) | 1979-10-26 | 1979-10-26 | Cembranolide diterpen |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS5661318A true JPS5661318A (en) | 1981-05-26 |
| JPS6320213B2 JPS6320213B2 (enrdf_load_stackoverflow) | 1988-04-26 |
Family
ID=15221779
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP13843079A Granted JPS5661318A (en) | 1979-10-26 | 1979-10-26 | Cembranolide diterpen |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS5661318A (enrdf_load_stackoverflow) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6317823A (ja) * | 1986-07-10 | 1988-01-25 | Mitsubishi Chem Ind Ltd | 抗固形腫瘍剤 |
| WO1993018651A1 (en) * | 1992-03-19 | 1993-09-30 | University Of Hawaii | Cyclic anti-tumor promoter compounds, compositions and methods for production and use |
| EP0462616A3 (enrdf_load_stackoverflow) * | 1990-06-20 | 1994-04-20 | Mitsubishi Chem Ind | |
| CN112876361A (zh) * | 2021-01-15 | 2021-06-01 | 宁波大学 | 西松烷型二萜类化合物及其制备方法和用途 |
| CN113402528A (zh) * | 2020-03-17 | 2021-09-17 | 中国医学科学院药物研究所 | 西松烷型大环二萜化合物及制备方法、药物组合物及用途 |
-
1979
- 1979-10-26 JP JP13843079A patent/JPS5661318A/ja active Granted
Non-Patent Citations (1)
| Title |
|---|
| CHEMICAL & PHARMACEUTICAL BULLETIN=1979 * |
Cited By (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6317823A (ja) * | 1986-07-10 | 1988-01-25 | Mitsubishi Chem Ind Ltd | 抗固形腫瘍剤 |
| US5300525A (en) * | 1986-07-10 | 1994-04-05 | Mitsubishi Kasei Corporation | Anti-solid tumor agents |
| US5387609A (en) * | 1986-07-10 | 1995-02-07 | Mitsubishi Kasei Corporation | Anti-solid tumor agents |
| EP0462616A3 (enrdf_load_stackoverflow) * | 1990-06-20 | 1994-04-20 | Mitsubishi Chem Ind | |
| WO1993018651A1 (en) * | 1992-03-19 | 1993-09-30 | University Of Hawaii | Cyclic anti-tumor promoter compounds, compositions and methods for production and use |
| US5276217A (en) * | 1992-03-19 | 1994-01-04 | University Of Hawaii | Cyclic anti-tumor promoter compounds, compositions and methods for production and use |
| US5349112A (en) * | 1992-03-19 | 1994-09-20 | University Of Hawaii | Cyclic anti-tumor promoter compounds, compositions and methods for production and use |
| CN113402528A (zh) * | 2020-03-17 | 2021-09-17 | 中国医学科学院药物研究所 | 西松烷型大环二萜化合物及制备方法、药物组合物及用途 |
| CN113402528B (zh) * | 2020-03-17 | 2023-09-26 | 中国医学科学院药物研究所 | 西松烷型大环二萜化合物及制备方法、药物组合物及用途 |
| CN112876361A (zh) * | 2021-01-15 | 2021-06-01 | 宁波大学 | 西松烷型二萜类化合物及其制备方法和用途 |
| CN112876361B (zh) * | 2021-01-15 | 2022-06-14 | 宁波大学 | 西松烷型二萜类化合物及其制备方法和用途 |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6320213B2 (enrdf_load_stackoverflow) | 1988-04-26 |
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