JPS5655339A

JPS5655339A - Separating method of bis hydroxyphenyl acetic acid and hydroxymandelic acid

Separating method of bis hydroxyphenyl acetic acid and hydroxymandelic acid

Info

Publication number: JPS5655339A
Authority: JP; Japan
Prior art keywords: acid; formula; ether; aqueous solution; bis
Prior art date: 1979-10-12
Legal status : Granted

Application number

JP13202479A

Other languages

English (en)

Japanese (ja)

Other versions

JPS63423B2 (en, 2012

Inventor

Kazuhisa Nakajima

Kazuaki Gogi

Toshio Yamamoto

Kazumasa Hirata

Current Assignee

Mitsubishi Chemical Corp

Original Assignee

Nippon Synthetic Chemical Industry Co Ltd

Priority date

1979-10-12

Filing date

1979-10-12

Publication date

1981-05-15

1979-10-12 Application filed by Nippon Synthetic Chemical Industry Co Ltd filed Critical Nippon Synthetic Chemical Industry Co Ltd

1979-10-12 Priority to JP13202479A priority Critical patent/JPS5655339A/ja

1981-05-15 Publication of JPS5655339A publication Critical patent/JPS5655339A/ja

1988-01-07 Publication of JPS63423B2 publication Critical patent/JPS63423B2/ja

Status Granted legal-status Critical Current

Links

VKVOJYUPJRVDPP-UHFFFAOYSA-N 2,2-dihydroxy-2-phenylacetic acid Chemical compound OC(=O)C(O)(O)C1=CC=CC=C1 VKVOJYUPJRVDPP-UHFFFAOYSA-N 0.000 title abstract 3
IWYDHOAUDWTVEP-UHFFFAOYSA-N mandelic acid Chemical compound OC(=O)C(O)C1=CC=CC=C1 IWYDHOAUDWTVEP-UHFFFAOYSA-N 0.000 title 2
RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 abstract 9
XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 abstract 6
150000001875 compounds Chemical class 0.000 abstract 4
QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 abstract 3
239000007864 aqueous solution Substances 0.000 abstract 3
239000003795 chemical substances by application Substances 0.000 abstract 3
238000000605 extraction Methods 0.000 abstract 3
235000019439 ethyl acetate Nutrition 0.000 abstract 2
ZHOOBJNSSOEZON-UHFFFAOYSA-N 2,2-bis(2-hydroxyphenyl)acetic acid Chemical compound C=1C=CC=C(O)C=1C(C(=O)O)C1=CC=CC=C1O ZHOOBJNSSOEZON-UHFFFAOYSA-N 0.000 abstract 1
ZAFNJMIOTHYJRJ-UHFFFAOYSA-N Diisopropyl ether Chemical compound CC(C)OC(C)C ZAFNJMIOTHYJRJ-UHFFFAOYSA-N 0.000 abstract 1
XBDQKXXYIPTUBI-UHFFFAOYSA-M Propionate Chemical compound CCC([O-])=O XBDQKXXYIPTUBI-UHFFFAOYSA-M 0.000 abstract 1
KXKVLQRXCPHEJC-UHFFFAOYSA-N acetic acid trimethyl ester Natural products COC(C)=O KXKVLQRXCPHEJC-UHFFFAOYSA-N 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
239000003905 agrochemical Substances 0.000 abstract 1
239000003513 alkali Substances 0.000 abstract 1
229910001854 alkali hydroxide Inorganic materials 0.000 abstract 1
150000008044 alkali metal hydroxides Chemical class 0.000 abstract 1
125000003545 alkoxy group Chemical group 0.000 abstract 1
125000000217 alkyl group Chemical group 0.000 abstract 1
229940079593 drug Drugs 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
229910052736 halogen Inorganic materials 0.000 abstract 1
150000002367 halogens Chemical class 0.000 abstract 1
239000000543 intermediate Substances 0.000 abstract 1
-1 methyl acetate Chemical compound 0.000 abstract 1
LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 abstract 1