JPS5653556B2 - - Google Patents

Info

Publication number
JPS5653556B2
JPS5653556B2 JP11849472A JP11849472A JPS5653556B2 JP S5653556 B2 JPS5653556 B2 JP S5653556B2 JP 11849472 A JP11849472 A JP 11849472A JP 11849472 A JP11849472 A JP 11849472A JP S5653556 B2 JPS5653556 B2 JP S5653556B2
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP11849472A
Other languages
Japanese (ja)
Other versions
JPS4858000A (de
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of JPS4858000A publication Critical patent/JPS4858000A/ja
Publication of JPS5653556B2 publication Critical patent/JPS5653556B2/ja
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/06—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with a hetero atom directly attached in position 14
    • C07D489/08—Oxygen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Addiction (AREA)
  • Psychiatry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP11849472A 1971-11-26 1972-11-24 Expired JPS5653556B2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US00202575A US3814768A (en) 1971-11-26 1971-11-26 6-methylene-6-desoxy dihydro morphine and codeine derivatives and pharmaceutically acceptable salts

Publications (2)

Publication Number Publication Date
JPS4858000A JPS4858000A (de) 1973-08-14
JPS5653556B2 true JPS5653556B2 (de) 1981-12-19

Family

ID=22750450

Family Applications (1)

Application Number Title Priority Date Filing Date
JP11849472A Expired JPS5653556B2 (de) 1971-11-26 1972-11-24

Country Status (7)

Country Link
US (1) US3814768A (de)
JP (1) JPS5653556B2 (de)
CA (1) CA974235A (de)
CH (1) CH578568A5 (de)
DE (1) DE2257715C2 (de)
FR (1) FR2160957B1 (de)
GB (1) GB1411129A (de)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5889377A (ja) * 1981-11-20 1983-05-27 Canon Inc ドツトプリンタ
JPH0158072B2 (de) * 1981-09-30 1989-12-08 Ricoh Kk

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4322426A (en) * 1980-04-28 1982-03-30 E. I. Du Pont De Nemours And Company 17-Substituted-6-desoxy-7,8-dihydro-6α-methylnoroxymorphone narcotic antagonists
US4477457A (en) * 1982-10-28 1984-10-16 E. I. Du Pont De Nemours And Company Method for inducing anorexia using nalmetrene
US4478840A (en) * 1983-10-11 1984-10-23 E. I. Du Pont De Nemours And Company Appetite suppressing compositions and methods
US4535157A (en) * 1983-11-01 1985-08-13 Key Pharmaceuticals, Inc. Process for making 6-desoxy-6-methylenenaloxone and 6-desoxy-6-methylenenaltrexone
US4639455A (en) * 1984-10-02 1987-01-27 Key Pharmaceuticals, Inc. Means of aiding in the prevention of sudden infant death syndrome
US4751307A (en) * 1985-01-17 1988-06-14 Mallinckrodt, Inc. Wittig-reaction processes
ATE84717T1 (de) * 1985-09-06 1993-02-15 Baker Cummins Pharma Verwendung von 6-methylen-6-desoxy-nus850906
US5028612A (en) * 1990-03-22 1991-07-02 Hillel Glover Method for treating emotional numbness
PT2561860T (pt) * 2002-05-31 2018-05-08 Titan Pharmaceuticals Inc Dispositivo polimérico implantável para a libertação prolongada de buprenorfina
EP1610791B1 (de) * 2003-03-31 2011-02-23 Titan Pharmaceuticals, Inc. Polymeres implantat zur verzögerten freisetzung von dopamin antagonisten
EP2317316A3 (de) * 2005-07-08 2011-06-15 Braincells, Inc. Verfahren zur Identifizierung von neurogenesemodulierenden Wirkstoffen und Bedingungen
CN103012416B (zh) * 2011-09-28 2015-07-01 辽宁海思科制药有限公司 一种盐酸纳美芬的制备方法
TWI560170B (en) * 2011-12-06 2016-12-01 Lundbeck & Co As H Process for recovery of nalmefene hydrochloride
CN102584840A (zh) * 2011-12-28 2012-07-18 南京优科生物医药有限公司 一种制备纳美芬化合物的方法
US20140005217A1 (en) 2012-06-27 2014-01-02 H. Lundbeck A/S Nalmefene for reduction of alcohol consumption in specific target populations
HU231191B1 (hu) 2013-04-15 2021-08-30 Szegedi Tudományegyetem Izotóp tartalmú morfin molekulák
CN103204859B (zh) * 2013-04-25 2015-12-02 四川海思科制药有限公司 一种盐酸纳美芬化合物及其制备方法
US20170042887A1 (en) 2014-04-22 2017-02-16 Otsuka Pharmaceutical. Co., Ltd. Combination of Brexpiprazole and Nalmefene and Use Thereof for Treating Substance-Related Disorders

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3162639A (en) * 1964-12-22 G-desoxy-ix-hydroxy-dihydromorphine

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3162639A (en) * 1964-12-22 G-desoxy-ix-hydroxy-dihydromorphine

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0158072B2 (de) * 1981-09-30 1989-12-08 Ricoh Kk
JPS5889377A (ja) * 1981-11-20 1983-05-27 Canon Inc ドツトプリンタ

Also Published As

Publication number Publication date
CA974235A (en) 1975-09-09
FR2160957B1 (de) 1975-11-28
FR2160957A1 (de) 1973-07-06
US3814768A (en) 1974-06-04
JPS4858000A (de) 1973-08-14
DE2257715C2 (de) 1985-06-05
DE2257715A1 (de) 1973-05-30
GB1411129A (en) 1975-10-22
CH578568A5 (de) 1976-08-13

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