CA974235A - Morphine derivatives - Google Patents

Morphine derivatives

Info

Publication number
CA974235A
CA974235A CA157,312A CA157312A CA974235A CA 974235 A CA974235 A CA 974235A CA 157312 A CA157312 A CA 157312A CA 974235 A CA974235 A CA 974235A
Authority
CA
Canada
Prior art keywords
morphine derivatives
morphine
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA157,312A
Other versions
CA157312S (en
Inventor
Jack Fishman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LEWENSTEIN EVALINA
MOZES J
Original Assignee
LEWENSTEIN EVALINA
MOZES J
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by LEWENSTEIN EVALINA, MOZES J filed Critical LEWENSTEIN EVALINA
Application granted granted Critical
Publication of CA974235A publication Critical patent/CA974235A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/06—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with a hetero atom directly attached in position 14
    • C07D489/08—Oxygen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Addiction (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA157,312A 1971-11-26 1972-11-23 Morphine derivatives Expired CA974235A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US00202575A US3814768A (en) 1971-11-26 1971-11-26 6-methylene-6-desoxy dihydro morphine and codeine derivatives and pharmaceutically acceptable salts

Publications (1)

Publication Number Publication Date
CA974235A true CA974235A (en) 1975-09-09

Family

ID=22750450

Family Applications (1)

Application Number Title Priority Date Filing Date
CA157,312A Expired CA974235A (en) 1971-11-26 1972-11-23 Morphine derivatives

Country Status (7)

Country Link
US (1) US3814768A (en)
JP (1) JPS5653556B2 (en)
CA (1) CA974235A (en)
CH (1) CH578568A5 (en)
DE (1) DE2257715C2 (en)
FR (1) FR2160957B1 (en)
GB (1) GB1411129A (en)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4322426A (en) * 1980-04-28 1982-03-30 E. I. Du Pont De Nemours And Company 17-Substituted-6-desoxy-7,8-dihydro-6α-methylnoroxymorphone narcotic antagonists
JPS5855258A (en) * 1981-09-30 1983-04-01 Ricoh Co Ltd Heat transfer type color printer
JPS5889377A (en) * 1981-11-20 1983-05-27 Canon Inc Dot printer
US4477457A (en) * 1982-10-28 1984-10-16 E. I. Du Pont De Nemours And Company Method for inducing anorexia using nalmetrene
US4478840A (en) * 1983-10-11 1984-10-23 E. I. Du Pont De Nemours And Company Appetite suppressing compositions and methods
US4535157A (en) * 1983-11-01 1985-08-13 Key Pharmaceuticals, Inc. Process for making 6-desoxy-6-methylenenaloxone and 6-desoxy-6-methylenenaltrexone
US4639455A (en) * 1984-10-02 1987-01-27 Key Pharmaceuticals, Inc. Means of aiding in the prevention of sudden infant death syndrome
US4751307A (en) * 1985-01-17 1988-06-14 Mallinckrodt, Inc. Wittig-reaction processes
WO1987001282A2 (en) * 1985-09-06 1987-03-12 Key Pharmaceuticals, Inc. Method and composition for providing sustained opioid antagonism
US5028612A (en) * 1990-03-22 1991-07-02 Hillel Glover Method for treating emotional numbness
EP1509182A4 (en) * 2002-05-31 2009-12-30 Titan Pharmaceuticals Inc Implantable polymeric device for sustained release of buprenorphine
MXPA05010450A (en) 2003-03-31 2005-11-04 Titan Pharmaceuticals Inc Implantable polymeric device for sustained release of dopamine agonist.
CA2614289A1 (en) * 2005-07-08 2007-01-18 Braincells, Inc. Methods for identifying agents and conditions that modulate neurogenesis
CN103012416B (en) * 2011-09-28 2015-07-01 辽宁海思科制药有限公司 Method for preparing high-purity nalmefene hydrochloride
TWI560170B (en) * 2011-12-06 2016-12-01 Lundbeck & Co As H Process for recovery of nalmefene hydrochloride
CN102584840A (en) * 2011-12-28 2012-07-18 南京优科生物医药有限公司 Method for preparing nalmefene compound
US20140005217A1 (en) 2012-06-27 2014-01-02 H. Lundbeck A/S Nalmefene for reduction of alcohol consumption in specific target populations
HU231191B1 (en) 2013-04-15 2021-08-30 Szegedi Tudományegyetem Isotope containing morphine molecules
CN103204859B (en) * 2013-04-25 2015-12-02 四川海思科制药有限公司 A kind of Nalmefene hydrochloride compound and preparation method thereof
TW201625252A (en) 2014-04-22 2016-07-16 大塚製藥股份有限公司 Medicament

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3162639A (en) * 1964-12-22 G-desoxy-ix-hydroxy-dihydromorphine

Also Published As

Publication number Publication date
FR2160957A1 (en) 1973-07-06
US3814768A (en) 1974-06-04
GB1411129A (en) 1975-10-22
CH578568A5 (en) 1976-08-13
FR2160957B1 (en) 1975-11-28
DE2257715C2 (en) 1985-06-05
JPS5653556B2 (en) 1981-12-19
DE2257715A1 (en) 1973-05-30
JPS4858000A (en) 1973-08-14

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