JPS5632461A - Preparation of 2,2,6,6-tetrakis (nicotinoyloxymethyl) cyclohexanol - Google Patents

Preparation of 2,2,6,6-tetrakis (nicotinoyloxymethyl) cyclohexanol

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Publication number
JPS5632461A
JPS5632461A JP10932579A JP10932579A JPS5632461A JP S5632461 A JPS5632461 A JP S5632461A JP 10932579 A JP10932579 A JP 10932579A JP 10932579 A JP10932579 A JP 10932579A JP S5632461 A JPS5632461 A JP S5632461A
Authority
JP
Japan
Prior art keywords
salt
chlorinating agent
nicotinic acid
agent
cyclohexanol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP10932579A
Other languages
Japanese (ja)
Inventor
Akira Hasegawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
TOHO IYAKU KENKYUSHO KK
Original Assignee
TOHO IYAKU KENKYUSHO KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by TOHO IYAKU KENKYUSHO KK filed Critical TOHO IYAKU KENKYUSHO KK
Priority to JP10932579A priority Critical patent/JPS5632461A/en
Publication of JPS5632461A publication Critical patent/JPS5632461A/en
Pending legal-status Critical Current

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Abstract

PURPOSE: To obtain the titled compound in high yields by a simple operation without fear of pollution, by reacting nicotinic acid or its salt with 2,2,6,6-tetramethylolcyclohexanol in the presence of a chlorinating agent or dehydrating agent.
CONSTITUTION: In the presence of a chlorinating agent such as thionyl chloride, sulfuryl chloride, phosphorus pentachloride, phosphorus trichloride, phosphorus oxychloride, or a dehydrating agent such as dicyclohexylcarbodiimide nicotinic acid or its salt is reacted with 2,2,6,6-tetramethylolcyclohexanol, to give the desired compound shown by the formula. An amount of nicotinic acid or its salt is 2W10mol based on 1mol of cyclohexanol as a raw material, and an amount of the chlorinating agent or dehydrating agent is about 1W5mol.
EFFECT: High-purity product is obtained. When a chlorinating agent is used, waste water is only neutralized by an alkali so that there is no problem at all.
USE: A compound effective against atherosclerosis.
COPYRIGHT: (C)1981,JPO&Japio
JP10932579A 1979-08-28 1979-08-28 Preparation of 2,2,6,6-tetrakis (nicotinoyloxymethyl) cyclohexanol Pending JPS5632461A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP10932579A JPS5632461A (en) 1979-08-28 1979-08-28 Preparation of 2,2,6,6-tetrakis (nicotinoyloxymethyl) cyclohexanol

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP10932579A JPS5632461A (en) 1979-08-28 1979-08-28 Preparation of 2,2,6,6-tetrakis (nicotinoyloxymethyl) cyclohexanol

Publications (1)

Publication Number Publication Date
JPS5632461A true JPS5632461A (en) 1981-04-01

Family

ID=14507360

Family Applications (1)

Application Number Title Priority Date Filing Date
JP10932579A Pending JPS5632461A (en) 1979-08-28 1979-08-28 Preparation of 2,2,6,6-tetrakis (nicotinoyloxymethyl) cyclohexanol

Country Status (1)

Country Link
JP (1) JPS5632461A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58210362A (en) * 1982-05-18 1983-12-07 エキップマン　エレクトロニク　モツール Starter for heat engine with supporter reinforcing member

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58210362A (en) * 1982-05-18 1983-12-07 エキップマン　エレクトロニク　モツール Starter for heat engine with supporter reinforcing member

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