JPS5632421A - Fractionation of plasma protein - Google Patents
Fractionation of plasma proteinInfo
- Publication number
- JPS5632421A JPS5632421A JP10878079A JP10878079A JPS5632421A JP S5632421 A JPS5632421 A JP S5632421A JP 10878079 A JP10878079 A JP 10878079A JP 10878079 A JP10878079 A JP 10878079A JP S5632421 A JPS5632421 A JP S5632421A
- Authority
- JP
- Japan
- Prior art keywords
- type
- plasma
- human
- albumin
- substance
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Abstract
PURPOSE: To purify human albumin and/or γ-globulin, by adding a zinc salt to an aqueous solution containing the human plasma proteins.
CONSTITUTION: The blood-type specific substance and pyrogenic substance are removed from human plasma proteins, by adding a zinc salt (e.g. zinc acetate, zinc sulfate, zinc chloride, etc.) to an aqueous solution containing human albumin and/or γ-globulin (e.g. derived from human blood, plasma, or placenta) to a final concentration of 0.5W50mM. The plasma proteins are precipitated by this treatment, and the type-specific substance and the pyrogenic substance existing in the plasma as impurities are left in the supernatant liquid. The blood-type-specific substance such as the A type, B type, H type, Le type, etc. which is a glucoprotein difficult to separate by conventional process, and the pyrogenic substance which is a lipo-polyglucoprotein constituting the cell wall of bacteria, can be separated by this process. The plasma protein such as albumin, γ-albumin, etc. recovered as precipitate, is further purified.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP10878079A JPS5632421A (en) | 1979-08-27 | 1979-08-27 | Fractionation of plasma protein |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP10878079A JPS5632421A (en) | 1979-08-27 | 1979-08-27 | Fractionation of plasma protein |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS5632421A true JPS5632421A (en) | 1981-04-01 |
Family
ID=14493283
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP10878079A Pending JPS5632421A (en) | 1979-08-27 | 1979-08-27 | Fractionation of plasma protein |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5632421A (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ITMI20082015A1 (en) * | 2008-11-13 | 2010-05-14 | Mac Pharma S R L | HYALURONIC ACID WITH LOW ENDOTOSSINE CONTENT AND HIGH CAPACITY OF WATER ABSORPTION. |
CN104807692A (en) * | 2014-01-29 | 2015-07-29 | 希森美康株式会社 | Method of recovering peptide and method of deteting peptide |
-
1979
- 1979-08-27 JP JP10878079A patent/JPS5632421A/en active Pending
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ITMI20082015A1 (en) * | 2008-11-13 | 2010-05-14 | Mac Pharma S R L | HYALURONIC ACID WITH LOW ENDOTOSSINE CONTENT AND HIGH CAPACITY OF WATER ABSORPTION. |
CN104807692A (en) * | 2014-01-29 | 2015-07-29 | 希森美康株式会社 | Method of recovering peptide and method of deteting peptide |
JP2015140320A (en) * | 2014-01-29 | 2015-08-03 | シスメックス株式会社 | Method for recovering peptide |
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