JPS5626833A - Preparation of 3-vinylbenzophenone - Google Patents
Preparation of 3-vinylbenzophenoneInfo
- Publication number
- JPS5626833A JPS5626833A JP10182179A JP10182179A JPS5626833A JP S5626833 A JPS5626833 A JP S5626833A JP 10182179 A JP10182179 A JP 10182179A JP 10182179 A JP10182179 A JP 10182179A JP S5626833 A JPS5626833 A JP S5626833A
- Authority
- JP
- Japan
- Prior art keywords
- meta
- halostyrene
- haloacetophenone
- benzonitrile
- reacted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
PURPOSE: To obtain the titled substance in high yield from an inexpensive raw material without using toxic substances, by reducting meta-haloacetophenone, dehydrating the reduction product into a meta-halostyrene, reacting the meta- halostyrene with Mg and subsequently benzonitrile, and hydrolyzing the reaction product.
CONSTITUTION: A meta-haloacetophenone is educed by metal hydride or hydrogen in the presence of a catalyst, etc., to be converted into an α-(m-halophenyl) ethyl alcohol, which is dehydrated in the vapor or liquid phase, to give a meta-halostyrene. Subsequently, the meta-halostyrene is reacted with metallic Mg, to be converted into a meta-vinylphenyl magnesium halide, which is reacted with benzonitrile, and then hydrolyzed, to give the titled substance.
EFFECT: Economical due to the saved trouble of waste liquor treatment or product purification in the absence of inorganic cyanides.
USE: An anti-inflammatory agent. Raw material for α-(m-benzoylphenyl)propionic acid which is an anti-inflammatory analgesic and antipyretic agent.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP10182179A JPS5626833A (en) | 1979-08-10 | 1979-08-10 | Preparation of 3-vinylbenzophenone |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP10182179A JPS5626833A (en) | 1979-08-10 | 1979-08-10 | Preparation of 3-vinylbenzophenone |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS5626833A true JPS5626833A (en) | 1981-03-16 |
Family
ID=14310775
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP10182179A Pending JPS5626833A (en) | 1979-08-10 | 1979-08-10 | Preparation of 3-vinylbenzophenone |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5626833A (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1990010615A1 (en) * | 1989-03-06 | 1990-09-20 | Nippon Petrochemicals Co., Ltd. | Production of alkenylbenzophenone |
WO1990010614A1 (en) * | 1989-03-06 | 1990-09-20 | Nippon Petrochemicals Co., Ltd. | PRODUCTION OF α-(3-BENZOYLPHENYL)PROPIONIC ACID DERIVATIVE |
-
1979
- 1979-08-10 JP JP10182179A patent/JPS5626833A/en active Pending
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1990010615A1 (en) * | 1989-03-06 | 1990-09-20 | Nippon Petrochemicals Co., Ltd. | Production of alkenylbenzophenone |
WO1990010614A1 (en) * | 1989-03-06 | 1990-09-20 | Nippon Petrochemicals Co., Ltd. | PRODUCTION OF α-(3-BENZOYLPHENYL)PROPIONIC ACID DERIVATIVE |
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