JPS5625164A - Tetrahydroisoquinoline compound and its preparation - Google Patents
Tetrahydroisoquinoline compound and its preparationInfo
- Publication number
- JPS5625164A JPS5625164A JP10151379A JP10151379A JPS5625164A JP S5625164 A JPS5625164 A JP S5625164A JP 10151379 A JP10151379 A JP 10151379A JP 10151379 A JP10151379 A JP 10151379A JP S5625164 A JPS5625164 A JP S5625164A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- compound
- preparation
- tetrahydroisoquinoline
- incorporate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- -1 Tetrahydroisoquinoline compound Chemical class 0.000 title 1
- UWYZHKAOTLEWKK-UHFFFAOYSA-N tetrahydro-isoquinoline Natural products C1=CC=C2CNCCC2=C1 UWYZHKAOTLEWKK-UHFFFAOYSA-N 0.000 title 1
- 102000004190 Enzymes Human genes 0.000 abstract 2
- 108090000790 Enzymes Proteins 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- FMSYUXRKRQVGBX-AWEZNQCLSA-N (3s)-2-[3-acetylsulfanyl-2-(acetylsulfanylmethyl)propanoyl]-6,7-dihydroxy-3,4-dihydro-1h-isoquinoline-3-carboxylic acid Chemical compound OC1=C(O)C=C2C[C@@H](C(O)=O)N(C(=O)C(CSC(C)=O)CSC(=O)C)CC2=C1 FMSYUXRKRQVGBX-AWEZNQCLSA-N 0.000 abstract 1
- 206010020772 Hypertension Diseases 0.000 abstract 1
- 241001465754 Metazoa Species 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 238000003745 diagnosis Methods 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 231100000053 low toxicity Toxicity 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 abstract 1
- 150000003526 tetrahydroisoquinolines Chemical class 0.000 abstract 1
- 238000011282 treatment Methods 0.000 abstract 1
Landscapes
- Other In-Based Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP10151379A JPS5625164A (en) | 1979-08-08 | 1979-08-08 | Tetrahydroisoquinoline compound and its preparation |
| DE8080300933T DE3063420D1 (en) | 1979-03-26 | 1980-03-25 | Tetrahydroisoquinolines, their production and the compounds and pharmaceutical compositions containing them for use in the prevention or treatment of hypertension |
| AT80300933T ATE3546T1 (de) | 1979-03-26 | 1980-03-25 | Tetrahydroisochinolin-derivate, ihre herstellung und sie enthaltende pharmazeutische zusammensetzungen zur verwendung bei der vorbeugung und behandlung von erhoehtem blutdruck. |
| EP19800300933 EP0018104B1 (en) | 1979-03-26 | 1980-03-25 | Tetrahydroisoquinolines, their production and the compounds and pharmaceutical compositions containing them for use in the prevention or treatment of hypertension |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP10151379A JPS5625164A (en) | 1979-08-08 | 1979-08-08 | Tetrahydroisoquinoline compound and its preparation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS5625164A true JPS5625164A (en) | 1981-03-10 |
| JPS6320229B2 JPS6320229B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1988-04-26 |
Family
ID=14302626
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP10151379A Granted JPS5625164A (en) | 1979-03-26 | 1979-08-08 | Tetrahydroisoquinoline compound and its preparation |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS5625164A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS60179104A (ja) * | 1984-02-27 | 1985-09-13 | Nippon Atom Ind Group Co Ltd | 中空糸膜濾過装置の運転方法 |
-
1979
- 1979-08-08 JP JP10151379A patent/JPS5625164A/ja active Granted
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS60179104A (ja) * | 1984-02-27 | 1985-09-13 | Nippon Atom Ind Group Co Ltd | 中空糸膜濾過装置の運転方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6320229B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1988-04-26 |
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