JPS56167622A - Hypolipemic - Google Patents

Hypolipemic

Info

Publication number
JPS56167622A
JPS56167622A JP7152780A JP7152780A JPS56167622A JP S56167622 A JPS56167622 A JP S56167622A JP 7152780 A JP7152780 A JP 7152780A JP 7152780 A JP7152780 A JP 7152780A JP S56167622 A JPS56167622 A JP S56167622A
Authority
JP
Japan
Prior art keywords
formula
compound
lower alkyl
lipid
lower alkoxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP7152780A
Other languages
Japanese (ja)
Inventor
Sakae Wada
Hiroshi Nakakimura
Masuo Koizumi
Shunichi Hata
Kazuo Igusa
Yoshimitsu Iida
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chugai Pharmaceutical Co Ltd
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Priority to JP7152780A priority Critical patent/JPS56167622A/en
Publication of JPS56167622A publication Critical patent/JPS56167622A/en
Pending legal-status Critical Current

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Landscapes

  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:Compounds of formula I (R1 is H, lower alkoxy; R2 is hydroxyl, lower alkoxy).
EXAMPLE: 10, 11-Dihydro-4-methoxybenzo[ b, f ][ 1, 4 ]oxazepin-8-carboxylic ethyl ester.
USE: Hypolipemic: they are used to prevent and treat various kinds of diseases caused by high concentration of lipid and peroxidized lipid in blood such as arteriosclerosis, cerebral apoplexy, cardiopathy or hepatopathy.
PREPARATION: The reduction and subsequent cyclization of a novel diphenyl ether derivative of formula II (R3 is lower alkyl) gives the compound of formula I where R2 is lower alkyl. The novel compound of formula II is obtained by reaction between a compound of formula III (Z is alkali metal atom) and another compound of forfula IV (X is halogen).
COPYRIGHT: (C)1981,JPO&Japio
JP7152780A 1980-05-30 1980-05-30 Hypolipemic Pending JPS56167622A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP7152780A JPS56167622A (en) 1980-05-30 1980-05-30 Hypolipemic

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP7152780A JPS56167622A (en) 1980-05-30 1980-05-30 Hypolipemic

Publications (1)

Publication Number Publication Date
JPS56167622A true JPS56167622A (en) 1981-12-23

Family

ID=13463285

Family Applications (1)

Application Number Title Priority Date Filing Date
JP7152780A Pending JPS56167622A (en) 1980-05-30 1980-05-30 Hypolipemic

Country Status (1)

Country Link
JP (1) JPS56167622A (en)

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