JPS56147790A - Cephalosporin type compound, its preparation, and antimicrobial agent comprising it - Google Patents

Cephalosporin type compound, its preparation, and antimicrobial agent comprising it

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Publication number
JPS56147790A
JPS56147790A JP4859980A JP4859980A JPS56147790A JP S56147790 A JPS56147790 A JP S56147790A JP 4859980 A JP4859980 A JP 4859980A JP 4859980 A JP4859980 A JP 4859980A JP S56147790 A JPS56147790 A JP S56147790A
Authority
JP
Japan
Prior art keywords
compound shown
formula
antimicrobial agent
preparation
type compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP4859980A
Other languages
Japanese (ja)
Inventor
Yoshimasa Machida
Isao Saito
Seiichiro Nomoto
Shigeto Negi
Takeo Kanai
Kyosuke Kito
Kamamasa Katsu
Yukio Ooya
Takeshi Nagasu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eisai Co Ltd
Original Assignee
Eisai Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eisai Co Ltd filed Critical Eisai Co Ltd
Priority to JP4859980A priority Critical patent/JPS56147790A/en
Publication of JPS56147790A publication Critical patent/JPS56147790A/en
Pending legal-status Critical Current

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  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:A compound shown by the formula I (R1 is optionally substituted nitrogen-containing hetrocyclic thio; R2 is H or OH; R3-R5 are H, OH, or acyloxy) or its compound.
EXAMPLE: 7β-[ D-2-( 6,7-Dihydroxychromono- 3-carboxyamide )-2-phenylacetamide]-3-[2-(5-methyl-1,3,4-thiadiazolyl)thiomethyl]-Δ3-cephem-4-carboxylic acid.
USE: Antimicrobial agent. Effective against Gram-positive and Gram-negative bacterium. Especially effective against Pseudomonas aeruginosa, Serratia marcescens, P- roteus morgani, etc.
PROCESS: For example, a compound shown by the formula II or its reactive derivative is reacted with a compound shown by the formula III, to give a compound shown by the formula I. The reaction is carried out in a solvent, e.g., acetone, etc., and, if necessary, in the presence of a base.
COPYRIGHT: (C)1981,JPO&Japio
JP4859980A 1980-04-15 1980-04-15 Cephalosporin type compound, its preparation, and antimicrobial agent comprising it Pending JPS56147790A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP4859980A JPS56147790A (en) 1980-04-15 1980-04-15 Cephalosporin type compound, its preparation, and antimicrobial agent comprising it

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP4859980A JPS56147790A (en) 1980-04-15 1980-04-15 Cephalosporin type compound, its preparation, and antimicrobial agent comprising it

Publications (1)

Publication Number Publication Date
JPS56147790A true JPS56147790A (en) 1981-11-16

Family

ID=12807865

Family Applications (1)

Application Number Title Priority Date Filing Date
JP4859980A Pending JPS56147790A (en) 1980-04-15 1980-04-15 Cephalosporin type compound, its preparation, and antimicrobial agent comprising it

Country Status (1)

Country Link
JP (1) JPS56147790A (en)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4982687A (en) * 1972-12-21 1974-08-08
JPS5036487A (en) * 1973-08-09 1975-04-05
JPS54109995A (en) * 1978-01-16 1979-08-29 Sandoz Ag Novel penicillins and cephalosporins and their manufacture and use
JPS565487A (en) * 1979-06-26 1981-01-20 Eisai Co Ltd Cephalosporin compound, its preparation, and antimicrobial comprising it

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4982687A (en) * 1972-12-21 1974-08-08
JPS5036487A (en) * 1973-08-09 1975-04-05
JPS54109995A (en) * 1978-01-16 1979-08-29 Sandoz Ag Novel penicillins and cephalosporins and their manufacture and use
JPS565487A (en) * 1979-06-26 1981-01-20 Eisai Co Ltd Cephalosporin compound, its preparation, and antimicrobial comprising it

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