JPS56142240A - Production of diphenylmethane derivative - Google Patents

Production of diphenylmethane derivative

Info

Publication number
JPS56142240A
JPS56142240A JP4515080A JP4515080A JPS56142240A JP S56142240 A JPS56142240 A JP S56142240A JP 4515080 A JP4515080 A JP 4515080A JP 4515080 A JP4515080 A JP 4515080A JP S56142240 A JPS56142240 A JP S56142240A
Authority
JP
Japan
Prior art keywords
formula
compound
iii
hydrolysis
reaction
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP4515080A
Other languages
Japanese (ja)
Inventor
Tetsutaro Hayasaka
Kuniaki Saitou
Senichi Narita
Takao Goto
Shinichi Yamada
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Toa Eiyo Ltd
Original Assignee
Toa Eiyo Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toa Eiyo Ltd filed Critical Toa Eiyo Ltd
Priority to JP4515080A priority Critical patent/JPS56142240A/en
Publication of JPS56142240A publication Critical patent/JPS56142240A/en
Pending legal-status Critical Current

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  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

PURPOSE: The reaction of a lower alcohol with a novel diphenylmethane derivative is conducted in the presence of a T1(III) salt, when desired, followed by hydrolysis, to produce the titled compound used as a synthetic intermediate of anti-inflammatory inexpensively through shortened processes in high yield.
CONSTITUTION: The reaction of a lower alcohol with a compound of formula I (R1 is H, lower alkyl) is conducted in the presence of a T1(III) salt such as T1(III) trinitrate supported on K-10 (made by Sud Chemie Co.), when desired, followed by hydrolysis, to afford the titled derivative of formula II (R2 is H, lower alkyl). The compound of formula II is used as a synthetic intermediate of a compound of formula III. The compound of formula I is novel and obtained by making an acid chloride or the like act on o-benzylacetophenone in the presence of anhydrous aluminum chloride. The hydrolysis is carried out by a known method, e.g., using hydrochloric acid. Further, the reaction is preferably effected in the presence of an acid catalyst.
COPYRIGHT: (C)1981,JPO&Japio
JP4515080A 1980-04-08 1980-04-08 Production of diphenylmethane derivative Pending JPS56142240A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP4515080A JPS56142240A (en) 1980-04-08 1980-04-08 Production of diphenylmethane derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP4515080A JPS56142240A (en) 1980-04-08 1980-04-08 Production of diphenylmethane derivative

Publications (1)

Publication Number Publication Date
JPS56142240A true JPS56142240A (en) 1981-11-06

Family

ID=12711241

Family Applications (1)

Application Number Title Priority Date Filing Date
JP4515080A Pending JPS56142240A (en) 1980-04-08 1980-04-08 Production of diphenylmethane derivative

Country Status (1)

Country Link
JP (1) JPS56142240A (en)

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