JPS56142240A - Production of diphenylmethane derivative - Google Patents
Production of diphenylmethane derivativeInfo
- Publication number
- JPS56142240A JPS56142240A JP4515080A JP4515080A JPS56142240A JP S56142240 A JPS56142240 A JP S56142240A JP 4515080 A JP4515080 A JP 4515080A JP 4515080 A JP4515080 A JP 4515080A JP S56142240 A JPS56142240 A JP S56142240A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- compound
- iii
- hydrolysis
- reaction
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
PURPOSE: The reaction of a lower alcohol with a novel diphenylmethane derivative is conducted in the presence of a T1(III) salt, when desired, followed by hydrolysis, to produce the titled compound used as a synthetic intermediate of anti-inflammatory inexpensively through shortened processes in high yield.
CONSTITUTION: The reaction of a lower alcohol with a compound of formula I (R1 is H, lower alkyl) is conducted in the presence of a T1(III) salt such as T1(III) trinitrate supported on K-10 (made by Sud Chemie Co.), when desired, followed by hydrolysis, to afford the titled derivative of formula II (R2 is H, lower alkyl). The compound of formula II is used as a synthetic intermediate of a compound of formula III. The compound of formula I is novel and obtained by making an acid chloride or the like act on o-benzylacetophenone in the presence of anhydrous aluminum chloride. The hydrolysis is carried out by a known method, e.g., using hydrochloric acid. Further, the reaction is preferably effected in the presence of an acid catalyst.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP4515080A JPS56142240A (en) | 1980-04-08 | 1980-04-08 | Production of diphenylmethane derivative |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP4515080A JPS56142240A (en) | 1980-04-08 | 1980-04-08 | Production of diphenylmethane derivative |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS56142240A true JPS56142240A (en) | 1981-11-06 |
Family
ID=12711241
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP4515080A Pending JPS56142240A (en) | 1980-04-08 | 1980-04-08 | Production of diphenylmethane derivative |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS56142240A (en) |
-
1980
- 1980-04-08 JP JP4515080A patent/JPS56142240A/en active Pending
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