JPS56123973A - Novel tetrazol-5-ylthiol ester and its preparation - Google Patents
Novel tetrazol-5-ylthiol ester and its preparationInfo
- Publication number
- JPS56123973A JPS56123973A JP2730380A JP2730380A JPS56123973A JP S56123973 A JPS56123973 A JP S56123973A JP 2730380 A JP2730380 A JP 2730380A JP 2730380 A JP2730380 A JP 2730380A JP S56123973 A JPS56123973 A JP S56123973A
- Authority
- JP
- Japan
- Prior art keywords
- tetrazol
- formula
- ester
- ylthiol
- ethyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Cephalosporin Compounds (AREA)
Abstract
NEW MATERIAL:A tetrazol-5-ylthiol ester expressed by formula I [R1 is H, methyl, 2-(dimethylamino)ethyl, carboxymethyl, 2-(carboxy)ethyl, sulfomethyl or benzyl; R2 is saturated or unsaturated straight or branched chain alkyl, nuclear substituted or unsubstituted aryl group, nuclear substituted or unsubstituted aralkul or amino acid residue in which the functional group is substituted.].
EXAMPLE: 1-Methyl-1H-tetrazol-5-ylthiol ester of N-benzyloxycarbonyl-L-alanine.
USE: An acylating agent for an amine or hydrazine, particularly for an active ester, alcohol or phenol in the peptide synthesis.
PROCESS: A compound of formula II is reacted with a carboxylic acid of the formula R2COOH or a reactive derivative at the carboxyl group thereof.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2730380A JPS56123973A (en) | 1980-03-06 | 1980-03-06 | Novel tetrazol-5-ylthiol ester and its preparation |
DE8080106952T DE3062779D1 (en) | 1979-11-16 | 1980-11-11 | Novel tetrazole-5-thiol esters and process for preparing cefamandole using same |
EP19800106952 EP0029202B1 (en) | 1979-11-16 | 1980-11-11 | Novel tetrazole-5-thiol esters and process for preparing cefamandole using same |
AT80106952T ATE3044T1 (en) | 1979-11-16 | 1980-11-11 | TETRAZOLE-5-THIOL ESTER AND PROCESS USING THEM TO PRODUCTION CEPHAMANDOL. |
US06/236,542 US4351947A (en) | 1980-03-06 | 1981-02-20 | Tetrazole derivative |
US06/350,805 US4417047A (en) | 1980-03-06 | 1982-02-22 | Novel tetrazole-5-thiol ester and process for preparing cefamandole using same |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2730380A JPS56123973A (en) | 1980-03-06 | 1980-03-06 | Novel tetrazol-5-ylthiol ester and its preparation |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS56123973A true JPS56123973A (en) | 1981-09-29 |
Family
ID=12217316
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2730380A Pending JPS56123973A (en) | 1979-11-16 | 1980-03-06 | Novel tetrazol-5-ylthiol ester and its preparation |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS56123973A (en) |
-
1980
- 1980-03-06 JP JP2730380A patent/JPS56123973A/en active Pending
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