JPS56123973A - Novel tetrazol-5-ylthiol ester and its preparation - Google Patents

Novel tetrazol-5-ylthiol ester and its preparation

Info

Publication number
JPS56123973A
JPS56123973A JP2730380A JP2730380A JPS56123973A JP S56123973 A JPS56123973 A JP S56123973A JP 2730380 A JP2730380 A JP 2730380A JP 2730380 A JP2730380 A JP 2730380A JP S56123973 A JPS56123973 A JP S56123973A
Authority
JP
Japan
Prior art keywords
tetrazol
formula
ester
ylthiol
ethyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2730380A
Other languages
Japanese (ja)
Inventor
Kazuyuki Shibuya
Masahiro Murakami
Masateru Kobayashi
Takanori Sone
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Asahi Chemical Industry Co Ltd
Original Assignee
Asahi Chemical Industry Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asahi Chemical Industry Co Ltd filed Critical Asahi Chemical Industry Co Ltd
Priority to JP2730380A priority Critical patent/JPS56123973A/en
Priority to DE8080106952T priority patent/DE3062779D1/en
Priority to EP19800106952 priority patent/EP0029202B1/en
Priority to AT80106952T priority patent/ATE3044T1/en
Priority to US06/236,542 priority patent/US4351947A/en
Publication of JPS56123973A publication Critical patent/JPS56123973A/en
Priority to US06/350,805 priority patent/US4417047A/en
Pending legal-status Critical Current

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  • Cephalosporin Compounds (AREA)

Abstract

NEW MATERIAL:A tetrazol-5-ylthiol ester expressed by formula I [R1 is H, methyl, 2-(dimethylamino)ethyl, carboxymethyl, 2-(carboxy)ethyl, sulfomethyl or benzyl; R2 is saturated or unsaturated straight or branched chain alkyl, nuclear substituted or unsubstituted aryl group, nuclear substituted or unsubstituted aralkul or amino acid residue in which the functional group is substituted.].
EXAMPLE: 1-Methyl-1H-tetrazol-5-ylthiol ester of N-benzyloxycarbonyl-L-alanine.
USE: An acylating agent for an amine or hydrazine, particularly for an active ester, alcohol or phenol in the peptide synthesis.
PROCESS: A compound of formula II is reacted with a carboxylic acid of the formula R2COOH or a reactive derivative at the carboxyl group thereof.
COPYRIGHT: (C)1981,JPO&Japio
JP2730380A 1979-11-16 1980-03-06 Novel tetrazol-5-ylthiol ester and its preparation Pending JPS56123973A (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
JP2730380A JPS56123973A (en) 1980-03-06 1980-03-06 Novel tetrazol-5-ylthiol ester and its preparation
DE8080106952T DE3062779D1 (en) 1979-11-16 1980-11-11 Novel tetrazole-5-thiol esters and process for preparing cefamandole using same
EP19800106952 EP0029202B1 (en) 1979-11-16 1980-11-11 Novel tetrazole-5-thiol esters and process for preparing cefamandole using same
AT80106952T ATE3044T1 (en) 1979-11-16 1980-11-11 TETRAZOLE-5-THIOL ESTER AND PROCESS USING THEM TO PRODUCTION CEPHAMANDOL.
US06/236,542 US4351947A (en) 1980-03-06 1981-02-20 Tetrazole derivative
US06/350,805 US4417047A (en) 1980-03-06 1982-02-22 Novel tetrazole-5-thiol ester and process for preparing cefamandole using same

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2730380A JPS56123973A (en) 1980-03-06 1980-03-06 Novel tetrazol-5-ylthiol ester and its preparation

Publications (1)

Publication Number Publication Date
JPS56123973A true JPS56123973A (en) 1981-09-29

Family

ID=12217316

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2730380A Pending JPS56123973A (en) 1979-11-16 1980-03-06 Novel tetrazol-5-ylthiol ester and its preparation

Country Status (1)

Country Link
JP (1) JPS56123973A (en)

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