JPS56122372A - Prostaglandin i2 derivative - Google Patents
Prostaglandin i2 derivativeInfo
- Publication number
- JPS56122372A JPS56122372A JP2526580A JP2526580A JPS56122372A JP S56122372 A JPS56122372 A JP S56122372A JP 2526580 A JP2526580 A JP 2526580A JP 2526580 A JP2526580 A JP 2526580A JP S56122372 A JPS56122372 A JP S56122372A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- compound
- alkyl
- activity
- heptadeutero
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000003174 prostaglandin I2 derivatives Chemical class 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- 230000000694 effects Effects 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- 125000004800 4-bromophenyl group Chemical group [H]C1=C([H])C(*)=C([H])C([H])=C1Br 0.000 abstract 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- 150000001340 alkali metals Chemical class 0.000 abstract 1
- 229910052784 alkaline earth metal Inorganic materials 0.000 abstract 1
- 150000001342 alkaline earth metals Chemical class 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 239000002585 base Substances 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 239000008280 blood Substances 0.000 abstract 1
- 210000001772 blood platelet Anatomy 0.000 abstract 1
- 230000015271 coagulation Effects 0.000 abstract 1
- 238000005345 coagulation Methods 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 238000006704 dehydrohalogenation reaction Methods 0.000 abstract 1
- ZUOUZKKEUPVFJK-UHFFFAOYSA-N diphenyl Chemical group C1=CC=CC=C1C1=CC=CC=C1 ZUOUZKKEUPVFJK-UHFFFAOYSA-N 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 210000004051 gastric juice Anatomy 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- KAQKFAOMNZTLHT-OZUDYXHBSA-N prostaglandin I2 Chemical compound O1\C(=C/CCCC(O)=O)C[C@@H]2[C@@H](/C=C/[C@@H](O)CCCCC)[C@H](O)C[C@@H]21 KAQKFAOMNZTLHT-OZUDYXHBSA-N 0.000 abstract 1
- 230000028327 secretion Effects 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
- 230000000304 vasodilatating effect Effects 0.000 abstract 1
Landscapes
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Furan Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2526580A JPS56122372A (en) | 1980-03-03 | 1980-03-03 | Prostaglandin i2 derivative |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2526580A JPS56122372A (en) | 1980-03-03 | 1980-03-03 | Prostaglandin i2 derivative |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS56122372A true JPS56122372A (en) | 1981-09-25 |
| JPH021144B2 JPH021144B2 (cs) | 1990-01-10 |
Family
ID=12161190
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2526580A Granted JPS56122372A (en) | 1980-03-03 | 1980-03-03 | Prostaglandin i2 derivative |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS56122372A (cs) |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5295644A (en) * | 1976-02-04 | 1977-08-11 | Upjohn Co | Composition and method |
-
1980
- 1980-03-03 JP JP2526580A patent/JPS56122372A/ja active Granted
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5295644A (en) * | 1976-02-04 | 1977-08-11 | Upjohn Co | Composition and method |
Also Published As
| Publication number | Publication date |
|---|---|
| JPH021144B2 (cs) | 1990-01-10 |
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