JPS56118051A - 5-fluorosalicylanilide derivative - Google Patents
5-fluorosalicylanilide derivativeInfo
- Publication number
- JPS56118051A JPS56118051A JP2325580A JP2325580A JPS56118051A JP S56118051 A JPS56118051 A JP S56118051A JP 2325580 A JP2325580 A JP 2325580A JP 2325580 A JP2325580 A JP 2325580A JP S56118051 A JPS56118051 A JP S56118051A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- compound shown
- fluorosalicylanilide
- derivative
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
NEW MATERIAL:The titled compound shown by the formula (R1 is H or acyl; R2 is alkyl; X is halogen).
EXAMPLE: 5-Fluoro-2'-methyl-chlorosalicylanilide.
USE: An antimicrobial agent. Especially having strong antimicrobial action on fungi. Characteristically having F at 5-position and an alkyl group at 2'-position.
PROCESS: 5-Fluorosalicylic acid is condensed with a 4-halogeno, 2-alkylaniline in the presence of a tertiary amine (e.g., pyridine, N-dimethylaniline, etc.) using a condensation agent of thionyl chloride, to give a compound shown by the formula. This method provides better yield and purity than other methods.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2325580A JPS56118051A (en) | 1980-02-25 | 1980-02-25 | 5-fluorosalicylanilide derivative |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2325580A JPS56118051A (en) | 1980-02-25 | 1980-02-25 | 5-fluorosalicylanilide derivative |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS56118051A true JPS56118051A (en) | 1981-09-16 |
Family
ID=12105483
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2325580A Pending JPS56118051A (en) | 1980-02-25 | 1980-02-25 | 5-fluorosalicylanilide derivative |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS56118051A (en) |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5726666A (en) * | 1980-06-09 | 1982-02-12 | Ciba Geigy Ag | Manufacture of 1-amino-8-hydroxynaphthalene- sulfonic acid having substituted amino group |
-
1980
- 1980-02-25 JP JP2325580A patent/JPS56118051A/en active Pending
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5726666A (en) * | 1980-06-09 | 1982-02-12 | Ciba Geigy Ag | Manufacture of 1-amino-8-hydroxynaphthalene- sulfonic acid having substituted amino group |
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