JPS57139053A - Preparation of benzanilide compound - Google Patents
Preparation of benzanilide compoundInfo
- Publication number
- JPS57139053A JPS57139053A JP2500081A JP2500081A JPS57139053A JP S57139053 A JPS57139053 A JP S57139053A JP 2500081 A JP2500081 A JP 2500081A JP 2500081 A JP2500081 A JP 2500081A JP S57139053 A JPS57139053 A JP S57139053A
- Authority
- JP
- Japan
- Prior art keywords
- substituted
- catalyst
- benzonitrile
- reaction
- benzanilide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Abstract
PURPOSE: To prepare a 2-substituted-benzanilide useful as an agricultural and horti-cultural fungicide, in high yield, by reacting an o-substituted or unsubstituted benzonitrile with an aniline compound and water in the presence or absence of a catalyst.
CONSTITUTION: Benzonitrile or an o-substituted-benzonitrile of formulaI(X is H, lower alkyl or halogen-substituted lower alkyl) is made to react with an aniline compound of formula II (Y is H, alkyl, alkoxy, etc.) and water in the presence or absence of a catalyst (e.g. hydrochloric acid, sulfuric acid, etc.) to obtain the 2-substituted-benzanilide of formula III. The reaction is preferably carried out in the presence of a catalyst in view of the yield, and the catalyst is effective in an amount of about 0.001W10M% of the benzonitrile. The reaction proceeds more economically by extracting the NH3 produced by the progress of the reaction, continuously or intermittently from the reaction system.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2500081A JPS57139053A (en) | 1981-02-24 | 1981-02-24 | Preparation of benzanilide compound |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2500081A JPS57139053A (en) | 1981-02-24 | 1981-02-24 | Preparation of benzanilide compound |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS57139053A true JPS57139053A (en) | 1982-08-27 |
Family
ID=12153693
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2500081A Pending JPS57139053A (en) | 1981-02-24 | 1981-02-24 | Preparation of benzanilide compound |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS57139053A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2016196459A (en) * | 2009-12-10 | 2016-11-24 | トラスティーズ・オブ・コロンビア・ユニバーシティ・イン・ザ・シティ・オブ・ニューヨーク | Histone acetyltransferase activators and uses thereof |
| US10640457B2 (en) | 2009-12-10 | 2020-05-05 | The Trustees Of Columbia University In The City Of New York | Histone acetyltransferase activators and uses thereof |
-
1981
- 1981-02-24 JP JP2500081A patent/JPS57139053A/en active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2016196459A (en) * | 2009-12-10 | 2016-11-24 | トラスティーズ・オブ・コロンビア・ユニバーシティ・イン・ザ・シティ・オブ・ニューヨーク | Histone acetyltransferase activators and uses thereof |
| US10640457B2 (en) | 2009-12-10 | 2020-05-05 | The Trustees Of Columbia University In The City Of New York | Histone acetyltransferase activators and uses thereof |
| US11034647B2 (en) | 2009-12-10 | 2021-06-15 | The Trustees Of Columbia University In The City Of New York | Histone acetyltransferase activators and uses thereof |
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