JPS56108765A - Acylated indole derivative, its preparation, and blood platelet coagulation inhibitor containing said derivative as effective component - Google Patents
Acylated indole derivative, its preparation, and blood platelet coagulation inhibitor containing said derivative as effective componentInfo
- Publication number
- JPS56108765A JPS56108765A JP835480A JP835480A JPS56108765A JP S56108765 A JPS56108765 A JP S56108765A JP 835480 A JP835480 A JP 835480A JP 835480 A JP835480 A JP 835480A JP S56108765 A JPS56108765 A JP S56108765A
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- compound
- formula
- derivative
- prevention
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 210000001772 blood platelet Anatomy 0.000 title abstract 2
- 150000002475 indoles Chemical class 0.000 title abstract 2
- 239000003130 blood coagulation factor inhibitor Substances 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 5
- 150000001875 compounds Chemical class 0.000 abstract 4
- -1 nitro, amino Chemical group 0.000 abstract 4
- 230000002265 prevention Effects 0.000 abstract 3
- 206010008190 Cerebrovascular accident Diseases 0.000 abstract 1
- 206010061216 Infarction Diseases 0.000 abstract 1
- 206010050902 Postoperative thrombosis Diseases 0.000 abstract 1
- 208000006011 Stroke Diseases 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000004423 acyloxy group Chemical class 0.000 abstract 1
- 125000002723 alicyclic group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000004644 alkyl sulfinyl group Chemical group 0.000 abstract 1
- 125000004414 alkyl thio group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 230000002490 cerebral effect Effects 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 230000015271 coagulation Effects 0.000 abstract 1
- 238000005345 coagulation Methods 0.000 abstract 1
- 230000002526 effect on cardiovascular system Effects 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 230000007574 infarction Effects 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 125000002924 primary amino group Chemical class [H]N([H])* 0.000 abstract 1
- LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical class FC(F)(F)* 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP835480A JPS56108765A (en) | 1980-01-29 | 1980-01-29 | Acylated indole derivative, its preparation, and blood platelet coagulation inhibitor containing said derivative as effective component |
EP19800302180 EP0022634B1 (en) | 1979-06-28 | 1980-06-27 | Acylated indole derivatives, processes for their preparation and pharmaceutical compositions and drugs comprising them |
DE8080302180T DE3062613D1 (en) | 1979-06-28 | 1980-06-27 | Acylated indole derivatives, processes for their preparation and pharmaceutical compositions and drugs comprising them |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP835480A JPS56108765A (en) | 1980-01-29 | 1980-01-29 | Acylated indole derivative, its preparation, and blood platelet coagulation inhibitor containing said derivative as effective component |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS56108765A true JPS56108765A (en) | 1981-08-28 |
JPS6241590B2 JPS6241590B2 (enrdf_load_stackoverflow) | 1987-09-03 |
Family
ID=11690884
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP835480A Granted JPS56108765A (en) | 1979-06-28 | 1980-01-29 | Acylated indole derivative, its preparation, and blood platelet coagulation inhibitor containing said derivative as effective component |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS56108765A (enrdf_load_stackoverflow) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS579761A (en) * | 1980-06-20 | 1982-01-19 | Teijin Ltd | Acylated indole derivative, its preparation, and pharmaceutical composition containing said compound as active component |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS54160311A (en) * | 1978-06-07 | 1979-12-19 | Nippon Zeon Co Ltd | Preparation of 3-hexyn-1-ol |
-
1980
- 1980-01-29 JP JP835480A patent/JPS56108765A/ja active Granted
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS54160311A (en) * | 1978-06-07 | 1979-12-19 | Nippon Zeon Co Ltd | Preparation of 3-hexyn-1-ol |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS579761A (en) * | 1980-06-20 | 1982-01-19 | Teijin Ltd | Acylated indole derivative, its preparation, and pharmaceutical composition containing said compound as active component |
Also Published As
Publication number | Publication date |
---|---|
JPS6241590B2 (enrdf_load_stackoverflow) | 1987-09-03 |
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