JPS5592383A - Novel substituted 55*22imidazolinee22yl** aminopyrimidine*its manufacture and its use as drug - Google Patents
Novel substituted 55*22imidazolinee22yl** aminopyrimidine*its manufacture and its use as drugInfo
- Publication number
- JPS5592383A JPS5592383A JP14717779A JP14717779A JPS5592383A JP S5592383 A JPS5592383 A JP S5592383A JP 14717779 A JP14717779 A JP 14717779A JP 14717779 A JP14717779 A JP 14717779A JP S5592383 A JPS5592383 A JP S5592383A
- Authority
- JP
- Japan
- Prior art keywords
- aminopyrimidine
- drug
- manufacture
- novel substituted
- substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/30—Halogen atoms or nitro radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/34—One oxygen atom
- C07D239/36—One oxygen atom as doubly bound oxygen atom or as unsubstituted hydroxy radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/42—One nitrogen atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Ophthalmology & Optometry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE2849537A DE2849537C2 (de) | 1978-11-15 | 1978-11-15 | Substituierte 5-(2-Imidazolin-2-yl)-aminopyrimidine, Verfahren zu deren Herstellung und diese enthaltende Arzneimittel |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5592383A true JPS5592383A (en) | 1980-07-12 |
JPS6354714B2 JPS6354714B2 (de) | 1988-10-28 |
Family
ID=6054732
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP14717779A Granted JPS5592383A (en) | 1978-11-15 | 1979-11-15 | Novel substituted 55*22imidazolinee22yl** aminopyrimidine*its manufacture and its use as drug |
Country Status (4)
Country | Link |
---|---|
JP (1) | JPS5592383A (de) |
BE (1) | BE880042A (de) |
DE (1) | DE2849537C2 (de) |
ZA (1) | ZA796148B (de) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6115832A (ja) * | 1984-06-23 | 1986-01-23 | エルテイーエス・ローマン・テラピー―ジユステーメ・ゲゼルシヤフト・ミツト・ベシユレンクテル・ハフツング・ウント・コンパニー・コマンジツトゲゼルシヤフト | 自己付着性膏剤 |
JPS6115833A (ja) * | 1984-06-23 | 1986-01-23 | エルテイーエス・ローマン・テラピー―ジユステーメ・ゲゼルシヤフト・ミツト・ベシユレンクテル・ハフツング・ウント・コンパニー・コマンジツトゲゼルシヤフト | 自己付着性膏剤 |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3016767A1 (de) * | 1980-04-30 | 1981-11-05 | Beiersdorf Ag, 2000 Hamburg | Pyrimidylthioharnstoffe, diese enthaltende arzneimittel und deren verwendung |
DE4423177A1 (de) * | 1994-07-01 | 1996-01-04 | Kali Chemie Pharma Gmbh | Antihyperglykämisch wirksame Arzneimittel |
DE19911371A1 (de) | 1999-03-15 | 2000-09-21 | Solvay Pharm Gmbh | Arzneimittel zur Behandlung von funktionellen Störungen und Erkrankungen der unteren Darmwege, insbesondere von damit einhergehenden abdominalen visceralen Schmerzen |
CA2487541A1 (en) | 2002-06-19 | 2003-12-31 | Solvay Pharmaceuticals Gmbh | Medicament for the treatment of diseases requiring inhibition or a reduction in the activity of ph value-regulating bicarbonate transporter proteins |
CN101370500A (zh) * | 2006-01-27 | 2009-02-18 | 弗·哈夫曼-拉罗切有限公司 | 2-咪唑化合物用于治疗cns障碍的用途 |
DE602006002738D1 (de) * | 2006-06-26 | 2008-10-23 | Chemagis Ltd | Verbessertes Verfahren zur Herstellung von Moxonidine |
BRPI0806940A2 (pt) | 2007-02-02 | 2014-05-06 | Hoffmann La Roche | 2-amino-oxazolinas como ligantes taar1 para distúrbios do snc |
CA2676944C (en) | 2007-02-15 | 2016-01-19 | F. Hoffmann-La Roche Ag | 2-aminooxazolines as taar1 ligands |
US8242153B2 (en) | 2008-07-24 | 2012-08-14 | Hoffmann-La Roche Inc. | 4,5-dihydro-oxazol-2YL derivatives |
US8354441B2 (en) | 2009-11-11 | 2013-01-15 | Hoffmann-La Roche Inc. | Oxazoline derivatives |
US9452980B2 (en) | 2009-12-22 | 2016-09-27 | Hoffmann-La Roche Inc. | Substituted benzamides |
DE102012215896A1 (de) | 2012-09-07 | 2014-03-13 | Wörwag Pharma GmbH & Co.KG | Moxonidinsynthese mit Hilfe organischer Basen |
EP2738165B1 (de) | 2012-12-03 | 2016-10-12 | WÖRWAG PHARMA GmbH & Co. KG | Verfahren mittels Phasentransferkatalyse |
EP2765131B1 (de) | 2013-02-08 | 2016-11-23 | Arevipharma GmbH | Verfahren zur Herstellung von Moxonidin |
KR102537050B1 (ko) | 2016-03-17 | 2023-05-26 | 에프. 호프만-라 로슈 아게 | Taar의 작용제로서 활성을 갖는 5-에틸-4-메틸-피라졸-3-카복스아미드 유도체 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE754832A (fr) * | 1969-08-14 | 1971-02-15 | Beecham Group Ltd | Iminazolines |
BE503170A (de) * | 1975-09-02 |
-
1978
- 1978-11-15 DE DE2849537A patent/DE2849537C2/de not_active Expired
-
1979
- 1979-11-14 BE BE0/198116A patent/BE880042A/fr not_active IP Right Cessation
- 1979-11-15 JP JP14717779A patent/JPS5592383A/ja active Granted
- 1979-11-15 ZA ZA00796148A patent/ZA796148B/xx unknown
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6115832A (ja) * | 1984-06-23 | 1986-01-23 | エルテイーエス・ローマン・テラピー―ジユステーメ・ゲゼルシヤフト・ミツト・ベシユレンクテル・ハフツング・ウント・コンパニー・コマンジツトゲゼルシヤフト | 自己付着性膏剤 |
JPS6115833A (ja) * | 1984-06-23 | 1986-01-23 | エルテイーエス・ローマン・テラピー―ジユステーメ・ゲゼルシヤフト・ミツト・ベシユレンクテル・ハフツング・ウント・コンパニー・コマンジツトゲゼルシヤフト | 自己付着性膏剤 |
Also Published As
Publication number | Publication date |
---|---|
JPS6354714B2 (de) | 1988-10-28 |
DE2849537A1 (de) | 1980-05-22 |
BE880042A (fr) | 1980-05-14 |
ZA796148B (en) | 1980-11-26 |
DE2849537C2 (de) | 1983-03-17 |
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