JPS5592345A - Preparation of optically-active cyclopropanecarboxylic acid - Google Patents
Preparation of optically-active cyclopropanecarboxylic acidInfo
- Publication number
- JPS5592345A JPS5592345A JP89479A JP89479A JPS5592345A JP S5592345 A JPS5592345 A JP S5592345A JP 89479 A JP89479 A JP 89479A JP 89479 A JP89479 A JP 89479A JP S5592345 A JPS5592345 A JP S5592345A
- Authority
- JP
- Japan
- Prior art keywords
- acid
- optically
- cyclopropanecarboxylic acid
- organic solvent
- active
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
PURPOSE: To obtain the optically-active title compound of high optical purity, having high insecticidal activity as an acid component of pyrethroid insecticides, by reacting an optically-active organic base with a cyclopropanecarboxylic acid and resolving the products taking advantage of the solubility difference.
CONSTITUTION: An optically-active organic base of formula II (R1WR2 are H or lower alkyl), such as (+)-α-(p-methylbenzyl)-benzylamine, is reacted with an equimolar amount of a cyclopropanecarboxylic acid of formula I (R is 1W6C lower alkyl), such as (±)-cis.trans-2,2-dimethyl-3-n-butoxycyclopropanecarboxylic acid to form a salt, from which crystal of (+) amine salt of (+)-cyclocarboxylic acid is obtained using an organic solvent such as ethanol. The crystal is decomposed with an alkali or a mineral acid, and extracted with an organic solvent. Subsequently, an aqueous layer is decomposed with a alkali or an acid and extracted with an organic solvent, it obtain (+)-cyclopropanecarboxylic acid.
COPYRIGHT: (C)1980,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP89479A JPS5592345A (en) | 1979-01-06 | 1979-01-06 | Preparation of optically-active cyclopropanecarboxylic acid |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP89479A JPS5592345A (en) | 1979-01-06 | 1979-01-06 | Preparation of optically-active cyclopropanecarboxylic acid |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5592345A true JPS5592345A (en) | 1980-07-12 |
JPS6218537B2 JPS6218537B2 (en) | 1987-04-23 |
Family
ID=11486378
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP89479A Granted JPS5592345A (en) | 1979-01-06 | 1979-01-06 | Preparation of optically-active cyclopropanecarboxylic acid |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5592345A (en) |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS4848449A (en) * | 1971-10-19 | 1973-07-09 |
-
1979
- 1979-01-06 JP JP89479A patent/JPS5592345A/en active Granted
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS4848449A (en) * | 1971-10-19 | 1973-07-09 |
Also Published As
Publication number | Publication date |
---|---|
JPS6218537B2 (en) | 1987-04-23 |
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