JPS5585592A - Demethylmaytansinoid compound - Google Patents
Demethylmaytansinoid compoundInfo
- Publication number
- JPS5585592A JPS5585592A JP16078778A JP16078778A JPS5585592A JP S5585592 A JPS5585592 A JP S5585592A JP 16078778 A JP16078778 A JP 16078778A JP 16078778 A JP16078778 A JP 16078778A JP S5585592 A JPS5585592 A JP S5585592A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- compound
- demethylmaytansinoid
- maytansinoid
- bacillus
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000001875 compounds Chemical class 0.000 title abstract 4
- 241000193830 Bacillus <bacterium> Species 0.000 abstract 1
- 241000194107 Bacillus megaterium Species 0.000 abstract 1
- 241000187747 Streptomyces Species 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 230000000842 anti-protozoal effect Effects 0.000 abstract 1
- 230000002622 anti-tumorigenesis Effects 0.000 abstract 1
- 239000003904 antiprotozoal agent Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 231100000053 low toxicity Toxicity 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 abstract 1
- 244000005700 microbiome Species 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 239000011541 reaction mixture Substances 0.000 abstract 1
- 238000003756 stirring Methods 0.000 abstract 1
- LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 abstract 1
Landscapes
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Priority Applications (13)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP16078778A JPS5585592A (en) | 1978-12-22 | 1978-12-22 | Demethylmaytansinoid compound |
| GR58533A GR63147B (en) | 1978-03-24 | 1979-03-07 | Preparation process of demethyl maytansinoids |
| ES478706A ES478706A1 (es) | 1978-03-24 | 1979-03-16 | Un metodo para producir un compuesto desmetilmaitansinoide. |
| CA000323717A CA1144096A (en) | 1978-03-24 | 1979-03-19 | Demethyl maytansinoids |
| AU45246/79A AU519911B2 (en) | 1978-03-24 | 1979-03-19 | Demethyl maytansinoids |
| PL1979214307A PL124051B1 (en) | 1978-03-24 | 1979-03-22 | Process for preparing novel demethylmaytansynoidic compounds |
| PT69382A PT69382A (en) | 1978-03-24 | 1979-03-22 | Demethyl maytansinoids |
| EP79300469A EP0004466B1 (en) | 1978-03-24 | 1979-03-23 | Demethyl maytansinoids and methods for producing them |
| AT0219179A AT362872B (de) | 1978-03-24 | 1979-03-23 | Verfahren zur herstellung von neuen demethylmaytansinoiden |
| DE7979300469T DE2961940D1 (en) | 1978-03-24 | 1979-03-23 | Demethyl maytansinoids and methods for producing them |
| DK121279A DK121279A (da) | 1978-03-24 | 1979-03-23 | Demethylmaytansinoider og fremgangsmaade til fremstilling deraf |
| US06/153,522 US4307016A (en) | 1978-03-24 | 1980-05-27 | Demethyl maytansinoids |
| US06/290,943 US4361650A (en) | 1978-03-24 | 1981-08-07 | Fermentation process of preparing demethyl maytansinoids |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP16078778A JPS5585592A (en) | 1978-12-22 | 1978-12-22 | Demethylmaytansinoid compound |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS5585592A true JPS5585592A (en) | 1980-06-27 |
| JPS6213958B2 JPS6213958B2 (enrdf_load_stackoverflow) | 1987-03-30 |
Family
ID=15722432
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP16078778A Granted JPS5585592A (en) | 1978-03-24 | 1978-12-22 | Demethylmaytansinoid compound |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS5585592A (enrdf_load_stackoverflow) |
-
1978
- 1978-12-22 JP JP16078778A patent/JPS5585592A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6213958B2 (enrdf_load_stackoverflow) | 1987-03-30 |
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