JPS5622777A - Novel antibiotic "bactobolin" and its preparation - Google Patents

Novel antibiotic "bactobolin" and its preparation

Info

Publication number
JPS5622777A
JPS5622777A JP9737879A JP9737879A JPS5622777A JP S5622777 A JPS5622777 A JP S5622777A JP 9737879 A JP9737879 A JP 9737879A JP 9737879 A JP9737879 A JP 9737879A JP S5622777 A JPS5622777 A JP S5622777A
Authority
JP
Japan
Prior art keywords
bactobolin
antibiotic
preparation
growth
gram
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP9737879A
Other languages
Japanese (ja)
Other versions
JPS6219428B2 (en
Inventor
Hamao Umezawa
Tomio Takeuchi
Masa Hamada
Shinichi Kondo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Microbial Chemistry Research Foundation
Original Assignee
Microbial Chemistry Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Microbial Chemistry Research Foundation filed Critical Microbial Chemistry Research Foundation
Priority to JP9737879A priority Critical patent/JPS5622777A/en
Publication of JPS5622777A publication Critical patent/JPS5622777A/en
Publication of JPS6219428B2 publication Critical patent/JPS6219428B2/ja
Granted legal-status Critical Current

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  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pyrane Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:Bactobolin, a novel antibiotic of the formula.
USE: Antibiotic: bactobolin inhibits the growth of wide ranges of bacteria including Gram-negative and Gram-positive ones. Further, it is also useful as anticarcinostatic, because of its activity of inhibiting the growth of various kinds of cancer cells including mouse leukemia L-1210 cells.
PREPARATION: A bacteria that belongs to Pseudomonas and produces bactobolin is cultured in a liquid culture medium containing neutritions, for example, containing 1.5% maltose, 0.3% yeast essence, 1.0%NZ amine and 0.3% sodium chloride at a pH of 7.4, preferably at 20W35°C, to produce bactobolin in the medium. Then, the antibiotic is separated from the culture mixture. The antibiotic is colorless needle and decomposes at 196W197°C.
COPYRIGHT: (C)1981,JPO&Japio
JP9737879A 1979-08-01 1979-08-01 Novel antibiotic "bactobolin" and its preparation Granted JPS5622777A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP9737879A JPS5622777A (en) 1979-08-01 1979-08-01 Novel antibiotic "bactobolin" and its preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP9737879A JPS5622777A (en) 1979-08-01 1979-08-01 Novel antibiotic "bactobolin" and its preparation

Publications (2)

Publication Number Publication Date
JPS5622777A true JPS5622777A (en) 1981-03-03
JPS6219428B2 JPS6219428B2 (en) 1987-04-28

Family

ID=14190841

Family Applications (1)

Application Number Title Priority Date Filing Date
JP9737879A Granted JPS5622777A (en) 1979-08-01 1979-08-01 Novel antibiotic "bactobolin" and its preparation

Country Status (1)

Country Link
JP (1) JPS5622777A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10099352B2 (en) 2015-05-20 2018-10-16 Jorg Hohmann Torque wrench system

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10099352B2 (en) 2015-05-20 2018-10-16 Jorg Hohmann Torque wrench system

Also Published As

Publication number Publication date
JPS6219428B2 (en) 1987-04-28

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